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The map label for this gene is kdsD [H]

Identifier: 66767643

GI number: 66767643

Start: 1604525

End: 1605526

Strand: Reverse

Name: kdsD [H]

Synonym: XC_1316

Alternate gene names: 66767643

Gene position: 1605526-1604525 (Counterclockwise)

Preceding gene: 77761147

Following gene: 66767642

Centisome position: 31.18

GC content: 70.66

Gene sequence:

>1002_bases
ATGGCCGTCTCGCACCTGCCCTCCGCCACCGTCAGCGACGCCAGCCTGGTCGCCAGCGGGCAGCGCGTGCTCGAGATCGA
GCAGGCGGCCCTGGCCGCGCTGGGCGCACGCATCGGTGCGCCGTTTGCCGCCGCCTGCCGGCTGGTGCTGGCCTCGCGCG
GGCGGGTGGTCGCCACCGGCATGGGCAAATCCGGGCATATCGCGCGCAAGATCGCCGCCACCCTGGCCTCCACCGGCACC
CCGGCGTTCTTCGTGCACCCGGGCGAGGCCGGGCATGGCGACCTGGGCATGATCACCGAGGCCGACATCGTGCTGGCGTT
GTCGTATTCGGGCGAATCGGACGAAGTCCGCATGCTGCTGCCGGTGCTCAAGCGCCAGGGCAACCCGATCATCGCGATGA
CCGGCCGCCCCGCCTCCACCCTGGCGCAGGCCGCCGACGTGCACCTGGATGTCAGCGTGTCTGCCGAAGCCTGCCCCCTG
CACCTGGCGCCGACCTCCAGCACCACCGCCTCATTGGCGATGGGCGATGCGTTGGCGGTGGCCCTGCTGGACGCGCGCGG
CTTCACCGCAGACGACTTCGCCCGCTCGCATCCGGCCGGTAGCCTGGGGCGCCGCCTGCTGCTGCACATCACCGATGTGA
TGCACGGCGGCGACGAGCTGCCGCGCGTGCGCGAGGACGCCAGCCTGAGCGAGGCGCTGATGGAGATGAGCCGCAAGCGC
CTGGGCATGACCGCCGTGGTGGACGCGCAAGAGCGGCTGATCGGCCTGTTCACCGACGGCGATCTGCGCCGCGCGCTGGA
CAGCGACATCGACGTGCGCAGCGCCGGCATTGCCGAGGTGATGACCCGCAACCCCAAGACCATCGGTGCCGACCAGCTGG
CCGCCGAGGCCGCGCGGCTGATGGAGGACTACAAGATCAATGGCCTGATCGTGGTCGATGCGCAGCAGCGCGCGGTCGGC
GCATTGAACATTCACGACCTGTTGCGCGCCAAGGTGGTTTAA

Upstream 100 bases:

>100_bases
TCAGGCAAGCCGGATTCGATGAGTTTACGGATGGTTTCGGCGTCCAAAGGGCGTTTCCTCATAAAATGAGCGCACATTCT
ACTCTTCACCCGAGCCCTGC

Downstream 100 bases:

>100_bases
CAGGTTCAGTTTTCAACCGCCGGACCCCGTTCTCACCGATTCGTGCCGATGCCCTATTCCCCCCTGCAAGACCTTCCTGC
CGACCTCATCGACCGTGCCG

Product: polysialic acid capsule expression protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAVSHLPSATVSDASLVASGQRVLEIEQAALAALGARIGAPFAAACRLVLASRGRVVATGMGKSGHIARKIAATLASTGT
PAFFVHPGEAGHGDLGMITEADIVLALSYSGESDEVRMLLPVLKRQGNPIIAMTGRPASTLAQAADVHLDVSVSAEACPL
HLAPTSSTTASLAMGDALAVALLDARGFTADDFARSHPAGSLGRRLLLHITDVMHGGDELPRVREDASLSEALMEMSRKR
LGMTAVVDAQERLIGLFTDGDLRRALDSDIDVRSAGIAEVMTRNPKTIGADQLAAEAARLMEDYKINGLIVVDAQQRAVG
ALNIHDLLRAKVV

Sequences:

>Translated_333_residues
MAVSHLPSATVSDASLVASGQRVLEIEQAALAALGARIGAPFAAACRLVLASRGRVVATGMGKSGHIARKIAATLASTGT
PAFFVHPGEAGHGDLGMITEADIVLALSYSGESDEVRMLLPVLKRQGNPIIAMTGRPASTLAQAADVHLDVSVSAEACPL
HLAPTSSTTASLAMGDALAVALLDARGFTADDFARSHPAGSLGRRLLLHITDVMHGGDELPRVREDASLSEALMEMSRKR
LGMTAVVDAQERLIGLFTDGDLRRALDSDIDVRSAGIAEVMTRNPKTIGADQLAAEAARLMEDYKINGLIVVDAQQRAVG
ALNIHDLLRAKVV
>Mature_332_residues
AVSHLPSATVSDASLVASGQRVLEIEQAALAALGARIGAPFAAACRLVLASRGRVVATGMGKSGHIARKIAATLASTGTP
AFFVHPGEAGHGDLGMITEADIVLALSYSGESDEVRMLLPVLKRQGNPIIAMTGRPASTLAQAADVHLDVSVSAEACPLH
LAPTSSTTASLAMGDALAVALLDARGFTADDFARSHPAGSLGRRLLLHITDVMHGGDELPRVREDASLSEALMEMSRKRL
GMTAVVDAQERLIGLFTDGDLRRALDSDIDVRSAGIAEVMTRNPKTIGADQLAAEAARLMEDYKINGLIVVDAQQRAVGA
LNIHDLLRAKVV

Specific function: Catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789588, Length=315, Percent_Identity=57.7777777777778, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI87082151, Length=319, Percent_Identity=47.0219435736677, Blast_Score=284, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000644
- InterPro:   IPR004800
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00571 CBS; PF01380 SIS [H]

EC number: =5.3.1.13 [H]

Molecular weight: Translated: 34713; Mature: 34582

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSHLPSATVSDASLVASGQRVLEIEQAALAALGARIGAPFAAACRLVLASRGRVVATG
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEC
MGKSGHIARKIAATLASTGTPAFFVHPGEAGHGDLGMITEADIVLALSYSGESDEVRMLL
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCEEEEEEECCCCCHHHHHH
PVLKRQGNPIIAMTGRPASTLAQAADVHLDVSVSAEACPLHLAPTSSTTASLAMGDALAV
HHHHCCCCCEEEECCCCHHHHHHHHCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHEE
ALLDARGFTADDFARSHPAGSLGRRLLLHITDVMHGGDELPRVREDASLSEALMEMSRKR
EEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHH
LGMTAVVDAQERLIGLFTDGDLRRALDSDIDVRSAGIAEVMTRNPKTIGADQLAAEAARL
CCCEEEEECHHHEEEEECCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
MEDYKINGLIVVDAQQRAVGALNIHDLLRAKVV
HHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AVSHLPSATVSDASLVASGQRVLEIEQAALAALGARIGAPFAAACRLVLASRGRVVATG
CCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEC
MGKSGHIARKIAATLASTGTPAFFVHPGEAGHGDLGMITEADIVLALSYSGESDEVRMLL
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCEEEEEEECCCCCHHHHHH
PVLKRQGNPIIAMTGRPASTLAQAADVHLDVSVSAEACPLHLAPTSSTTASLAMGDALAV
HHHHCCCCCEEEECCCCHHHHHHHHCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHEE
ALLDARGFTADDFARSHPAGSLGRRLLLHITDVMHGGDELPRVREDASLSEALMEMSRKR
EEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHH
LGMTAVVDAQERLIGLFTDGDLRRALDSDIDVRSAGIAEVMTRNPKTIGADQLAAEAARL
CCCEEEEECHHHEEEEECCCHHHHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
MEDYKINGLIVVDAQQRAVGALNIHDLLRAKVV
HHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]