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The map label for this gene is lptA [H]

Identifier: 66767640

GI number: 66767640

Start: 1602842

End: 1603378

Strand: Reverse

Name: lptA [H]

Synonym: XC_1313

Alternate gene names: 66767640

Gene position: 1603378-1602842 (Counterclockwise)

Preceding gene: 66767641

Following gene: 66767639

Centisome position: 31.14

GC content: 61.64

Gene sequence:

>537_bases
ATGAACCGAATGCTGCCCGCTAAACTGGCGTTTGCCGCACTGCTGCTGCCCGCATTGGCGATGGCCAAGACCAGCGATCG
CAATCAGCCGATGACGATCGACTCCAACAGCAACGATTGCAACATGCTCGATGACAGCGGCAAGTGCCGTTTCAGCGGCA
AGGTGGTGATCACCCAGGGCACGCTGGAAATCCACGCCGACACCGCCGACATCTTCCAGAAGAACGGCCAGACCGACCGC
GTAGTGCTCAACGGCAAGCAGGCCACGCTGAAGCAGGAGATGGACGACGGCGCGATGATGAACGGCCAGGCCGACAACAT
CGAATACAAGGTCGCCGACGAAATCATCATCCTCACCGGCAATTACAAGGTGGATTCGCCCAAGGGCACCAACGCTGGTC
AGCGCATGGTCTACAACACCAAGACCGGCAACATGCAGAGCGGAGGCGACGGCAGCCGCGTGCGCACCATCATCCAGCCC
AAGACTGCCGCGCCCGCCGCGGCGCCCGCACCGGCCAAGCCGCAGGGGAAGAAGTAA

Upstream 100 bases:

>100_bases
GTCACCATGCGCCGGCCGGGTATCATGCAAAGCGGGGTCGGCTTCGAGGCCGATCTCAAGACACGCCAGTACAAGCTCCT
TTCCCAGGTCAAGACCCGCT

Downstream 100 bases:

>100_bases
TGCTGGTCGCCACCGGTCTGCGCAAGAAATACAAGCAGCGCGAAGTGGTCAAGGAGTTCGGCCTGACCCTGGAGGCCGGC
GAAGTGGTCGGCCTGCTGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMTIDSNSNDCNMLDDSGKCRFSGKVVITQGTLEIHADTADIFQKNGQTDR
VVLNGKQATLKQEMDDGAMMNGQADNIEYKVADEIIILTGNYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQP
KTAAPAAAPAPAKPQGKK

Sequences:

>Translated_178_residues
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMTIDSNSNDCNMLDDSGKCRFSGKVVITQGTLEIHADTADIFQKNGQTDR
VVLNGKQATLKQEMDDGAMMNGQADNIEYKVADEIIILTGNYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQP
KTAAPAAAPAPAKPQGKK
>Mature_178_residues
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMTIDSNSNDCNMLDDSGKCRFSGKVVITQGTLEIHADTADIFQKNGQTDR
VVLNGKQATLKQEMDDGAMMNGQADNIEYKVADEIIILTGNYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQP
KTAAPAAAPAPAKPQGKK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=161, Percent_Identity=32.9192546583851, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 19044; Mature: 19044

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMTIDSNSNDCNMLDDSGKCRFSGKVVITQG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEECCCCCEEECCEEEEEEC
TLEIHADTADIFQKNGQTDRVVLNGKQATLKQEMDDGAMMNGQADNIEYKVADEIIILTG
EEEEECCHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEECCCCCCEEEEEECEEEEEEC
NYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQPKTAAPAAAPAPAKPQGKK
CEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRMLPAKLAFAALLLPALAMAKTSDRNQPMTIDSNSNDCNMLDDSGKCRFSGKVVITQG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEECCCCCEEECCEEEEEEC
TLEIHADTADIFQKNGQTDRVVLNGKQATLKQEMDDGAMMNGQADNIEYKVADEIIILTG
EEEEECCHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEECCCCCCEEEEEECEEEEEEC
NYKVDSPKGTNAGQRMVYNTKTGNMQSGGDGSRVRTIIQPKTAAPAAAPAPAKPQGKK
CEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]