Click here to switch to the map view.

The map label for this gene is sdaA [H]

Identifier: 66767582

GI number: 66767582

Start: 1536424

End: 1537806

Strand: Reverse

Name: sdaA [H]

Synonym: XC_1255

Alternate gene names: 66767582

Gene position: 1537806-1536424 (Counterclockwise)

Preceding gene: 66767584

Following gene: 66767581

Centisome position: 29.87

GC content: 64.5

Gene sequence:

>1383_bases
ATGGCTGTCAGTACGTTCGACCTGTTCAAGATCGGTATCGGTCCGAGTTCCTCGCATACCGTGGGGCCGATGCGCGCCGC
CGAGCGCTTCGTCCACCGCTGGTTGCTCGATACCGGCCGCTTGCAGGAGGTGACACGTCTGCGCGCCGAAGTTTTCGGCT
CGCTGGCATTGACCGGGCGCGGCCATGGCACCGACAAGGCGGTGCTGCTCGGGCTGGAAGGGCATCGCCCGAACCTGATC
GACCCGGATGTCATCCCCGCCACGCTCGAGCGCATCCGCAGCAGCAAGCGCATCAACCTGATGGGCCAGCATGAAATCAG
CTTCGACGAAAAGCGCGACCTGCCGATGAACAAGCGGCAGAAGCTGCCGTACCACACCAACGGCATGCGCTTCACCGCCT
ACGATGCAACCGAAGCGGTGATTGCCACGCGCGATTACTATTCGGTGGGCGGCGGTTTCGTGGTCAACCAGGACGACGCC
GCCGACGACCGCATCGTGGCCGACGAGACTCCGTTGCCCTACCCGTTCCTCAGCGGCGACGAGCTGCTGGCGCAGTGCGC
GCGCAGCGGCCTGAGCATTGCGCAACTGATGTTCGAGAACGAAAAGAGCTGGCGTAGCGAAGACGAGATCCGCGCCGGCC
TGCGGGAGCTGTGGAACGCCATGCAGTCGTGCGTGGCACGTGGCATTCGCGAAGAAGGCACCCTGCCCGGCGGCCTGAAC
GTCTCGCGCCGTGCGCCCGCGCTGTACCGCGAGCTCTCCTCCAAGCCCGAAGCGGCGATGCGCGACCCGTTGACCACGCT
GGATTGGGTCAACCTCTACGCACTCGCCGTCAACGAAGAAAATGCCGCAGGCGGCCGCGTGGTCACCGCGCCCACCAACG
GTGCAGCCGGCATCATTCCCTCGGTGCTGCATTACTTCGATCGTTTTTGCCCGGGCGCTTCGGAACAACGCATTTTCGAC
TTCCTGCTCACCGCAGCGGCAATCGGCATCCTGTACAAGGAAAACGCCTCGATTTCCGGTGCCGAAGTGGGCTGCCAGGG
CGAAGTGGGTGTGGCCTGCTCGATGGCCGCCGGCGGCCTGGTCGCCGCGCTCGGCGGCAACCCCGGGCAGATCGAGAATG
CAGCGGAAATCGGCATGGAGCACAACCTCGGCCTGACCTGCGACCCGATCGGCGGGCTGGTGCAGATCCCCTGCATCGAA
CGCAACGCGATGGGGGCAGTGAAAGCCATCAACGCCAGCCGCATGGCCATGCGTGGCGACGGCAAGCACAAGGTGTCACT
GGACAAGGTCATCAAGACCATGCGCGACACCGGCCGTGACATGCAGGACAAGTACAAGGAAACCAGCCGTGGCGGGCTGG
CGGTGAATGTCATCGAATGCTGA

Upstream 100 bases:

>100_bases
AGGGTCAGGGCCATGCGGGGGGTCTCATGCTGCGCTGCAGCCGTGCTGCGATCGCCAAGCGCTTAGAATAGCGGGCTTCT
TGCTCACCTCCCCGGCACGC

Downstream 100 bases:

>100_bases
GTCGGTGCGTGGCTTAGAGCGGCTAACAAAACGTAGCGAGCAGTCGTCAGGTGGGTGCGGACGGCGCGGAGGAACCGGAA
TGTAGGTGGGTACATGCCGA

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MAVSTFDLFKIGIGPSSSHTVGPMRAAERFVHRWLLDTGRLQEVTRLRAEVFGSLALTGRGHGTDKAVLLGLEGHRPNLI
DPDVIPATLERIRSSKRINLMGQHEISFDEKRDLPMNKRQKLPYHTNGMRFTAYDATEAVIATRDYYSVGGGFVVNQDDA
ADDRIVADETPLPYPFLSGDELLAQCARSGLSIAQLMFENEKSWRSEDEIRAGLRELWNAMQSCVARGIREEGTLPGGLN
VSRRAPALYRELSSKPEAAMRDPLTTLDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPSVLHYFDRFCPGASEQRIFD
FLLTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGGLVAALGGNPGQIENAAEIGMEHNLGLTCDPIGGLVQIPCIE
RNAMGAVKAINASRMAMRGDGKHKVSLDKVIKTMRDTGRDMQDKYKETSRGGLAVNVIEC

Sequences:

>Translated_460_residues
MAVSTFDLFKIGIGPSSSHTVGPMRAAERFVHRWLLDTGRLQEVTRLRAEVFGSLALTGRGHGTDKAVLLGLEGHRPNLI
DPDVIPATLERIRSSKRINLMGQHEISFDEKRDLPMNKRQKLPYHTNGMRFTAYDATEAVIATRDYYSVGGGFVVNQDDA
ADDRIVADETPLPYPFLSGDELLAQCARSGLSIAQLMFENEKSWRSEDEIRAGLRELWNAMQSCVARGIREEGTLPGGLN
VSRRAPALYRELSSKPEAAMRDPLTTLDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPSVLHYFDRFCPGASEQRIFD
FLLTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGGLVAALGGNPGQIENAAEIGMEHNLGLTCDPIGGLVQIPCIE
RNAMGAVKAINASRMAMRGDGKHKVSLDKVIKTMRDTGRDMQDKYKETSRGGLAVNVIEC
>Mature_459_residues
AVSTFDLFKIGIGPSSSHTVGPMRAAERFVHRWLLDTGRLQEVTRLRAEVFGSLALTGRGHGTDKAVLLGLEGHRPNLID
PDVIPATLERIRSSKRINLMGQHEISFDEKRDLPMNKRQKLPYHTNGMRFTAYDATEAVIATRDYYSVGGGFVVNQDDAA
DDRIVADETPLPYPFLSGDELLAQCARSGLSIAQLMFENEKSWRSEDEIRAGLRELWNAMQSCVARGIREEGTLPGGLNV
SRRAPALYRELSSKPEAAMRDPLTTLDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPSVLHYFDRFCPGASEQRIFDF
LLTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGGLVAALGGNPGQIENAAEIGMEHNLGLTCDPIGGLVQIPCIER
NAMGAVKAINASRMAMRGDGKHKVSLDKVIKTMRDTGRDMQDKYKETSRGGLAVNVIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=457, Percent_Identity=54.7045951859956, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=55.1422319474836, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1789161, Length=462, Percent_Identity=52.8138528138528, Blast_Score=480, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49789; Mature: 49658

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSTFDLFKIGIGPSSSHTVGPMRAAERFVHRWLLDTGRLQEVTRLRAEVFGSLALTGR
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECC
GHGTDKAVLLGLEGHRPNLIDPDVIPATLERIRSSKRINLMGQHEISFDEKRDLPMNKRQ
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHC
KLPYHTNGMRFTAYDATEAVIATRDYYSVGGGFVVNQDDAADDRIVADETPLPYPFLSGD
CCCEECCCEEEEEECCCCEEEEECCCEECCCCEEECCCCCCCCCEEECCCCCCCCCCCCH
ELLAQCARSGLSIAQLMFENEKSWRSEDEIRAGLRELWNAMQSCVARGIREEGTLPGGLN
HHHHHHHHCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCC
VSRRAPALYRELSSKPEAAMRDPLTTLDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIP
CCCCCHHHHHHHCCCCCHHHHCCCCHHHHEEEEEEEECCCCCCCCEEEECCCCCCHHHHH
SVLHYFDRFCPGASEQRIFDFLLTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGGL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEEECCCCE
VAALGGNPGQIENAAEIGMEHNLGLTCDPIGGLVQIPCIERNAMGAVKAINASRMAMRGD
EEEECCCCCCCCHHHHHCCCCCCCEEECCCCCEEECCEECCCCCCHHHHHCHHHHEECCC
GKHKVSLDKVIKTMRDTGRDMQDKYKETSRGGLAVNVIEC
CCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
AVSTFDLFKIGIGPSSSHTVGPMRAAERFVHRWLLDTGRLQEVTRLRAEVFGSLALTGR
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECC
GHGTDKAVLLGLEGHRPNLIDPDVIPATLERIRSSKRINLMGQHEISFDEKRDLPMNKRQ
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHC
KLPYHTNGMRFTAYDATEAVIATRDYYSVGGGFVVNQDDAADDRIVADETPLPYPFLSGD
CCCEECCCEEEEEECCCCEEEEECCCEECCCCEEECCCCCCCCCEEECCCCCCCCCCCCH
ELLAQCARSGLSIAQLMFENEKSWRSEDEIRAGLRELWNAMQSCVARGIREEGTLPGGLN
HHHHHHHHCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCC
VSRRAPALYRELSSKPEAAMRDPLTTLDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIP
CCCCCHHHHHHHCCCCCHHHHCCCCHHHHEEEEEEEECCCCCCCCEEEECCCCCCHHHHH
SVLHYFDRFCPGASEQRIFDFLLTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGGL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEEECCCCE
VAALGGNPGQIENAAEIGMEHNLGLTCDPIGGLVQIPCIERNAMGAVKAINASRMAMRGD
EEEECCCCCCCCHHHHHCCCCCCCEEECCCCCEEECCEECCCCCCHHHHHCHHHHEECCC
GKHKVSLDKVIKTMRDTGRDMQDKYKETSRGGLAVNVIEC
CCCEEEHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]