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The map label for this gene is recQ [H]

Identifier: 66767490

GI number: 66767490

Start: 1401404

End: 1403206

Strand: Reverse

Name: recQ [H]

Synonym: XC_1162

Alternate gene names: 66767490

Gene position: 1403206-1401404 (Counterclockwise)

Preceding gene: 66767491

Following gene: 66767489

Centisome position: 27.25

GC content: 67.5

Gene sequence:

>1803_bases
ATGTCTTCCCCCGCACACGAACTGCTCAGCCGCGTCTTCGGTTACGACGATTTCCGCGGCCCCCAGCAAGCCATTGTCGA
ACACGTCGCCGCCGGCAACGACGCGCTGGTTCTGATGCCCACCGGTGGCGGCAAGTCGCTGTGCTACCAGGTCCCGGCGC
TGTTGCGCGACGGCATCGGCATCGTGGTGTCGCCGCTGATCGCCCTGATGCAGGACCAGGTGGAAGCCCTGCGCCAGCTC
GGGGTGCGCGCCGAATTCCTCAACTCCACCCTGGATGCGGAAAACACCCAGCGGGTGGAACGCGCCCTGCTCTCGGGCGA
TCTGGACCTGCTGTACGTCGCACCGGAACGACTGCTCACCCCGCGCTTCCTGTCGCTGCTGGAACGTAGCCGCATCGCCT
TGTTCGCCATCGACGAAGCGCACTGCGTGTCGCAGTGGGGCCACGACTTCCGCCCGGAGTACCGCCAGCTCACCGTACTG
CACGAGCGTTGGCCACACATTCCGCGGATGGCATTGACGGCAACCGCCGACCCGCCCACCCAACGCGAGATCGCCGAGCG
CCTGGACCTGGTGGAGGCGCGCCACTTCGTCAGCTCGTTCGACCGCCCCAACATCCGCTACACCGTGGTGCAGAAGGACA
ACGCGCGCAAGCAGCTGCAGGAGTTCCTGGGCCGCCACCGCGGCTCGGCCGGCATCGTCTATGCGATGTCGCGGCGCAAA
GTGGAAGAAACCGCGCAACAGCTGTGTGCGCAAGGCTTCAATGCCCTGCCCTACCACGCCGGCCTGCCGGCGGAAGTGCG
CGCGGAGAACCAGCGCCGCTTCCTGCGCGAGGACGGCATCATCATGGCCGCCACGATCGCCTTCGGCATGGGCATCGACA
AGCCAGACGTGCGGTTCGTGGCGCACGTGGACCTGCCCAAATCGATGGAAGGCTATTACCAGGAAACCGGGCGTGCCGGC
CGCGATGGCGAGCCCGCCGAGGCATGGCTCTGCTATGGCCTGGGCGATGTGGTGCTGCTCAAGCAGATGATCGAACAGGG
CGAGGCCGCCGAAGAGCGCAAGCGCCTGGAACGCGCCAAGCTCGATCACCTGCTGGGCTACTGCGAGTCCATGCAGTGCC
GCCGCCAGGTGCTGCTGGCCGGCTTCGGCGAAACCTATCCCAAGCCCTGCGGCAACTGCGACAACTGCCTGACCCCGGCC
GCCGCCTGGGACGCCACCGTGGCCTCGCAGAAGGCGCTGAGCTGCGTGTATCGCAGCGGGCAGCGCTTCGGTGTGGGCCA
TCTGATCGACATCCTGCGCGGCAGCGAGAACGAGCGCATCAAGCAGCTCGGCCACGACCAGCTGAGCACCTACGGCATCG
GCCGCGACATGGACGAGCGTACCTGGCGCGGGGTGTTCCGCCAGCTGGTGGCTGCCAGCCTGCTGGAAGTCGACAGCGAA
GGCCACGGCGGCCTGCGCCTCACCGATGCCAGTCGCCAGGTACTCAAGGGCGAGCGCCAGGTGATGATGCGGCGCGAAAA
CCCGGCTGCCGGGCGAGAGCGCGACCGCGGCGCGCAACGCACCGGGCTGCCGGTGCAGCCGCAGGATCTGGGGCTGTTCA
ACGCCTTGCGCGGCCTGCGCGCGGAACTGGCCAAGGAGCAGAACGTGCCGGCCTTCGTGATCTTCCACGACAGCACACTG
CGCAATATCGCCGAACAACGGCCCACCAGCATCGATGCCCTCTCGCGTGTGGGCGGCATCGGCGGCGGCAAGCTGGCCCG
TTACGGTGCGCAACTGATCGAGATCGTGCGCGAACAGGGCTGA

Upstream 100 bases:

>100_bases
CTACCGCATCCACCACGGCGCGGCGATCCCCGACACACCACTGCGCAACACCGCCCGCATGACACCGGCCCGGGCTTGAC
CCGCGCGGTATCCTAGGCGG

Downstream 100 bases:

>100_bases
TGCGCCAGGTGTGTGTCGGCCCGGTGCCGCGGCCGGCACAACAATCCGCGGAAGCGACAGCGCGCATTCAATCTGCCGTT
GCTAGTTTCAGCGGAGCGAT

Product: DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIGIVVSPLIALMQDQVEALRQL
GVRAEFLNSTLDAENTQRVERALLSGDLDLLYVAPERLLTPRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVL
HERWPHIPRMALTATADPPTQREIAERLDLVEARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFVAHVDLPKSMEGYYQETGRAG
RDGEPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAKLDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPA
AAWDATVASQKALSCVYRSGQRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDMDERTWRGVFRQLVAASLLEVDSE
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERDRGAQRTGLPVQPQDLGLFNALRGLRAELAKEQNVPAFVIFHDSTL
RNIAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG

Sequences:

>Translated_600_residues
MSSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIGIVVSPLIALMQDQVEALRQL
GVRAEFLNSTLDAENTQRVERALLSGDLDLLYVAPERLLTPRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVL
HERWPHIPRMALTATADPPTQREIAERLDLVEARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFVAHVDLPKSMEGYYQETGRAG
RDGEPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAKLDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPA
AAWDATVASQKALSCVYRSGQRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDMDERTWRGVFRQLVAASLLEVDSE
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERDRGAQRTGLPVQPQDLGLFNALRGLRAELAKEQNVPAFVIFHDSTL
RNIAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG
>Mature_599_residues
SSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIGIVVSPLIALMQDQVEALRQLG
VRAEFLNSTLDAENTQRVERALLSGDLDLLYVAPERLLTPRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVLH
ERWPHIPRMALTATADPPTQREIAERLDLVEARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRKV
EETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFVAHVDLPKSMEGYYQETGRAGR
DGEPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAKLDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPAA
AWDATVASQKALSCVYRSGQRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDMDERTWRGVFRQLVAASLLEVDSEG
HGGLRLTDASRQVLKGERQVMMRRENPAAGRERDRGAQRTGLPVQPQDLGLFNALRGLRAELAKEQNVPAFVIFHDSTLR
NIAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=639, Percent_Identity=34.7417840375587, Blast_Score=352, Evalue=6e-97,
Organism=Homo sapiens, GI14591902, Length=415, Percent_Identity=38.3132530120482, Blast_Score=305, Evalue=7e-83,
Organism=Homo sapiens, GI14591904, Length=415, Percent_Identity=38.3132530120482, Blast_Score=305, Evalue=7e-83,
Organism=Homo sapiens, GI148612816, Length=425, Percent_Identity=41.8823529411765, Blast_Score=292, Evalue=6e-79,
Organism=Homo sapiens, GI51242943, Length=395, Percent_Identity=42.5316455696203, Blast_Score=276, Evalue=6e-74,
Organism=Homo sapiens, GI51242947, Length=395, Percent_Identity=42.5316455696203, Blast_Score=275, Evalue=7e-74,
Organism=Homo sapiens, GI169218196, Length=498, Percent_Identity=34.9397590361446, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI110735439, Length=498, Percent_Identity=34.9397590361446, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI284005309, Length=342, Percent_Identity=35.672514619883, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI13514831, Length=343, Percent_Identity=23.6151603498542, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI48994977, Length=597, Percent_Identity=46.0636515912898, Blast_Score=537, Evalue=1e-154,
Organism=Escherichia coli, GI87082221, Length=349, Percent_Identity=24.6418338108883, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=500, Percent_Identity=38.2, Blast_Score=341, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI71987997, Length=410, Percent_Identity=40.4878048780488, Blast_Score=295, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI71987993, Length=410, Percent_Identity=40.4878048780488, Blast_Score=295, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI32564293, Length=678, Percent_Identity=31.5634218289086, Blast_Score=291, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI17552866, Length=412, Percent_Identity=37.378640776699, Blast_Score=252, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6323844, Length=524, Percent_Identity=35.4961832061069, Blast_Score=331, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6324217, Length=344, Percent_Identity=23.546511627907, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646066, Length=625, Percent_Identity=35.68, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=452, Percent_Identity=38.4955752212389, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24664230, Length=452, Percent_Identity=38.4955752212389, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI62472181, Length=452, Percent_Identity=38.4955752212389, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21358123, Length=352, Percent_Identity=36.0795454545455, Blast_Score=198, Evalue=9e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66862; Mature: 66731

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIG
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
IVVSPLIALMQDQVEALRQLGVRAEFLNSTLDAENTQRVERALLSGDLDLLYVAPERLLT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECHHHHCC
PRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVLHERWPHIPRMALTATADPPT
HHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
QREIAERLDLVEARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHH
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCCEEE
AHVDLPKSMEGYYQETGRAGRDGEPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAK
EEECCCHHHHHHHHHHCCCCCCCCCHHHEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPAAAWDATVASQKALSCVYRSG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDMDERTWRGVFRQLVAASLLEVDSE
CCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERDRGAQRTGLPVQPQDLGLFNALRGLR
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHCCHHHHHHHHH
AELAKEQNVPAFVIFHDSTLRNIAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG
HHHHHHCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSPAHELLSRVFGYDDFRGPQQAIVEHVAAGNDALVLMPTGGGKSLCYQVPALLRDGIG
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
IVVSPLIALMQDQVEALRQLGVRAEFLNSTLDAENTQRVERALLSGDLDLLYVAPERLLT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECHHHHCC
PRFLSLLERSRIALFAIDEAHCVSQWGHDFRPEYRQLTVLHERWPHIPRMALTATADPPT
HHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
QREIAERLDLVEARHFVSSFDRPNIRYTVVQKDNARKQLQEFLGRHRGSAGIVYAMSRRK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHHH
VEETAQQLCAQGFNALPYHAGLPAEVRAENQRRFLREDGIIMAATIAFGMGIDKPDVRFV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCCEEE
AHVDLPKSMEGYYQETGRAGRDGEPAEAWLCYGLGDVVLLKQMIEQGEAAEERKRLERAK
EEECCCHHHHHHHHHHCCCCCCCCCHHHEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LDHLLGYCESMQCRRQVLLAGFGETYPKPCGNCDNCLTPAAAWDATVASQKALSCVYRSG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QRFGVGHLIDILRGSENERIKQLGHDQLSTYGIGRDMDERTWRGVFRQLVAASLLEVDSE
CCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GHGGLRLTDASRQVLKGERQVMMRRENPAAGRERDRGAQRTGLPVQPQDLGLFNALRGLR
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHCCHHHHHHHHH
AELAKEQNVPAFVIFHDSTLRNIAEQRPTSIDALSRVGGIGGGKLARYGAQLIEIVREQG
HHHHHHCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]