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The map label for this gene is lysA [H]

Identifier: 66767431

GI number: 66767431

Start: 1329650

End: 1330933

Strand: Reverse

Name: lysA [H]

Synonym: XC_1103

Alternate gene names: 66767431

Gene position: 1330933-1329650 (Counterclockwise)

Preceding gene: 66767432

Following gene: 66767414

Centisome position: 25.85

GC content: 68.54

Gene sequence:

>1284_bases
ATGAGTCTGCAGATCGATGCCACGGCGGTGCGCGCAGCGGTGGCGCAGTTACGTGCGCACAGCGACGCCCCGCTATGTGC
GTACGTCTACGACCTGGCCGCACTGGATGCGCACGCAGCATGGATGCGTGCGCAGCTGCCGCCCGGCTGCACGCTGTTCT
ACGCCGCCAAGGCCAATGCCGAACCGCAGATCCTGCAGACGCTGGCGCCGTACGTGGATGGGTTCGAAGCCGCATCCGGT
GGCGAGCTCGCCTGGCTGCACCAGCAGCAACCGGATGCGGCGTTGCTGTTTGGTGGGCCGGGCAAACTGGAGAGCGAACT
GGCGCAGGCCGTGCGCCTGCCCGACTGCACCGTGCATGTGGAAAGCCTGGGCGAATTGCAGCGGCTGGCGGCCATTGCGC
GACAGATCGCCCAGCCCGACCGCCGGCGCATCCCGGTGTTCCTGCGCATGAACATCGCCGTGCCCGGTGCACAGACCACG
CGTTTGATGATGGGCGGCCAACCATCGCCATTCGGGCTGGACCCGGACGACCTGGATGCTGCGCTGCTGCAGCTACGCGC
CAGCCCGGCACTGGAGTTGCGCGGCTTCCATTTCCACCTGATGTCGCACCAACGCGACGCCGCCGCGCAGCTGCACCTGA
TCGCGGCGTATCTGCGCACCGTGCAGCACTGGCGGCAGCGCCATGGCCTGGGCCCGCTGCTGGTCAATGCCGGCGGCGGC
TTCGGCGTGGACTATCTGACGCCAGAGGCCTCGTTCGACTGGGCAGGCTTCTGCGCCGGGCTGCCCGCGGTGCTGCACGC
GCACGGCGACGGCCTGCAACTGCGCCTGGAACCGGGCCGCTATGTCAGCGCCAGCTGCGGCTGGTACCTGATGGAGGTGC
TGGACATCAAGCGCAGCCACGGCGCGTGGTTTGCGATTGCCCGTGGCGGCACCCATCACTTCCGCACGCCGGCCGCGCAA
GGCCACGACCATCCCTGCGTGGTGGTACGCGGCACACATGCACCGGTGCTGCGCGACACCCCGGTCACCCTGGTCGGCCA
GCTCTGCACGCCCAAGGATGTACTGGCCCGCAATCAGCGCGTTGCAGCGCTCGCTCCCGGCGACTGCCTGGCCTTCCCGC
TGGCGGGTGCGTATGCGTGGAATATTTCGCATCAGCAGTTCCTGATGCACCCGCCACCGCAGATGGTGTTTTTGCCGGTA
CACGCTCAGGCAACCGCCACCACCGGCACGCGGATGTCGGCGCGCAGGTCGGCTTCGGCCACGGTCTCGGGGTCGTCGAG
GTAG

Upstream 100 bases:

>100_bases
ACCTGGGCACGCGGCTGTTGCAACGTGCAGATCGTCAATCGGACTACACCGCCCTGCCCAACCCCATCGCGCCAATGCAT
GCCGTGCAGCAGGTGGCCGC

Downstream 100 bases:

>100_bases
AGGTAGTGCAGGGGTGCGTCGCGCAGTGCGTGACCGCTGCCGGGCAGCCAGTCGGCGAGCAGGCGGTCGAGCGCGTCTTC
CAGCCCGGCATAGCTGCCGG

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSLQIDATAVRAAVAQLRAHSDAPLCAYVYDLAALDAHAAWMRAQLPPGCTLFYAAKANAEPQILQTLAPYVDGFEAASG
GELAWLHQQQPDAALLFGGPGKLESELAQAVRLPDCTVHVESLGELQRLAAIARQIAQPDRRRIPVFLRMNIAVPGAQTT
RLMMGGQPSPFGLDPDDLDAALLQLRASPALELRGFHFHLMSHQRDAAAQLHLIAAYLRTVQHWRQRHGLGPLLVNAGGG
FGVDYLTPEASFDWAGFCAGLPAVLHAHGDGLQLRLEPGRYVSASCGWYLMEVLDIKRSHGAWFAIARGGTHHFRTPAAQ
GHDHPCVVVRGTHAPVLRDTPVTLVGQLCTPKDVLARNQRVAALAPGDCLAFPLAGAYAWNISHQQFLMHPPPQMVFLPV
HAQATATTGTRMSARRSASATVSGSSR

Sequences:

>Translated_427_residues
MSLQIDATAVRAAVAQLRAHSDAPLCAYVYDLAALDAHAAWMRAQLPPGCTLFYAAKANAEPQILQTLAPYVDGFEAASG
GELAWLHQQQPDAALLFGGPGKLESELAQAVRLPDCTVHVESLGELQRLAAIARQIAQPDRRRIPVFLRMNIAVPGAQTT
RLMMGGQPSPFGLDPDDLDAALLQLRASPALELRGFHFHLMSHQRDAAAQLHLIAAYLRTVQHWRQRHGLGPLLVNAGGG
FGVDYLTPEASFDWAGFCAGLPAVLHAHGDGLQLRLEPGRYVSASCGWYLMEVLDIKRSHGAWFAIARGGTHHFRTPAAQ
GHDHPCVVVRGTHAPVLRDTPVTLVGQLCTPKDVLARNQRVAALAPGDCLAFPLAGAYAWNISHQQFLMHPPPQMVFLPV
HAQATATTGTRMSARRSASATVSGSSR
>Mature_426_residues
SLQIDATAVRAAVAQLRAHSDAPLCAYVYDLAALDAHAAWMRAQLPPGCTLFYAAKANAEPQILQTLAPYVDGFEAASGG
ELAWLHQQQPDAALLFGGPGKLESELAQAVRLPDCTVHVESLGELQRLAAIARQIAQPDRRRIPVFLRMNIAVPGAQTTR
LMMGGQPSPFGLDPDDLDAALLQLRASPALELRGFHFHLMSHQRDAAAQLHLIAAYLRTVQHWRQRHGLGPLLVNAGGGF
GVDYLTPEASFDWAGFCAGLPAVLHAHGDGLQLRLEPGRYVSASCGWYLMEVLDIKRSHGAWFAIARGGTHHFRTPAAQG
HDHPCVVVRGTHAPVLRDTPVTLVGQLCTPKDVLARNQRVAALAPGDCLAFPLAGAYAWNISHQQFLMHPPPQMVFLPVH
AQATATTGTRMSARRSASATVSGSSR

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 45993; Mature: 45862

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQIDATAVRAAVAQLRAHSDAPLCAYVYDLAALDAHAAWMRAQLPPGCTLFYAAKANA
CCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
EPQILQTLAPYVDGFEAASGGELAWLHQQQPDAALLFGGPGKLESELAQAVRLPDCTVHV
CHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEH
ESLGELQRLAAIARQIAQPDRRRIPVFLRMNIAVPGAQTTRLMMGGQPSPFGLDPDDLDA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHH
ALLQLRASPALELRGFHFHLMSHQRDAAAQLHLIAAYLRTVQHWRQRHGLGPLLVNAGGG
HHHHHHCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
FGVDYLTPEASFDWAGFCAGLPAVLHAHGDGLQLRLEPGRYVSASCGWYLMEVLDIKRSH
CCCCEECCCCCCCHHHHHHCCHHHEEECCCCEEEEECCCCEEECCCHHHHHHHHHHHCCC
GAWFAIARGGTHHFRTPAAQGHDHPCVVVRGTHAPVLRDTPVTLVGQLCTPKDVLARNQR
CCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHCCCE
VAALAPGDCLAFPLAGAYAWNISHQQFLMHPPPQMVFLPVHAQATATTGTRMSARRSASA
EEEECCCCEEEEECCCEEEECCCCCEEEECCCCCEEEEEEECCEECCCCCCHHHHCCCCE
TVSGSSR
EECCCCC
>Mature Secondary Structure 
SLQIDATAVRAAVAQLRAHSDAPLCAYVYDLAALDAHAAWMRAQLPPGCTLFYAAKANA
CEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
EPQILQTLAPYVDGFEAASGGELAWLHQQQPDAALLFGGPGKLESELAQAVRLPDCTVHV
CHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEH
ESLGELQRLAAIARQIAQPDRRRIPVFLRMNIAVPGAQTTRLMMGGQPSPFGLDPDDLDA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHH
ALLQLRASPALELRGFHFHLMSHQRDAAAQLHLIAAYLRTVQHWRQRHGLGPLLVNAGGG
HHHHHHCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
FGVDYLTPEASFDWAGFCAGLPAVLHAHGDGLQLRLEPGRYVSASCGWYLMEVLDIKRSH
CCCCEECCCCCCCHHHHHHCCHHHEEECCCCEEEEECCCCEEECCCHHHHHHHHHHHCCC
GAWFAIARGGTHHFRTPAAQGHDHPCVVVRGTHAPVLRDTPVTLVGQLCTPKDVLARNQR
CCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHCCCE
VAALAPGDCLAFPLAGAYAWNISHQQFLMHPPPQMVFLPVHAQATATTGTRMSARRSASA
EEEECCCCEEEEECCCEEEECCCCCEEEECCCCCEEEEEEECCEECCCCCCHHHHCCCCE
TVSGSSR
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]