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The map label for this gene is yrpG [H]

Identifier: 66766625

GI number: 66766625

Start: 333721

End: 334689

Strand: Reverse

Name: yrpG [H]

Synonym: XC_0281

Alternate gene names: 66766625

Gene position: 334689-333721 (Counterclockwise)

Preceding gene: 66766628

Following gene: 66766624

Centisome position: 6.5

GC content: 65.74

Gene sequence:

>969_bases
ATGCCCCACTCCCGTGCGCTTGGCCGCTCCGGCCTGCAAGTCCAGCCGATCGTGTTCGGTGGCAACGTGTTTGGCTGGAG
CGCCGACGAGGCCACCTCGTTCGCGTTGCTCGACGCCTTCGTCGATGCCGGCTTCAACATGATCGATACCGCCGACGCGT
ACTCCGGTTGGGTGCCCGGCAATCGCGGTGGCGAATCGGAAACCATCATCGGCCGCTGGCTGGCCCGCAGCGGCAAACGC
GACAAGGTGCTGATCGCCACCAAGGTCGCCAAGTGGAGCGAACACCCGGGCCTGTCGCCGGACAACATCGCAGCGGCGGT
GGAAGATTCGCTGTCGCGCCTGCAGACCGATGTGATCGATCTGTACCAGGCACACGAAGACGACGAATCGATTCCGCTGG
AAGCCACGCTGGCGGCATTCGGCCGGCTGATCGAACAGGGCAAGGTGCGTGCGATCGGCGCCTCCAACTACACGGCAGCG
CGCCTGCGCGATGCGCTGGATGTGTCGGCGCAATACAACCTGCCGCGCTATGAAAGCCTGCAGCCCGAATACAACCTCTA
CGACCGCGCCGGCTTCGAAGAGGAATTGGAACCGCTGGTGCAGGAACGCGGCCTGGGCGTGATCAGTTACTACTCGCTGG
CCAGCGGTTTTCTCACCGGCAAGTACCGCAGCGCCGATGACGCCGGCAAGAGCAGCGCGCGTGGTGCCTCGGTGGTCAAG
CAATACGTCAATCCGCGTGGCTTGCGCATCCTGCAGGCGCTGGATGATCTGGCCGCCACCCACACCGCCACGCCTGCACA
GATTGCGCTGGCGTGGTTGATCGCGCGCCCCAGTGTCACCGCGCCGATCGTCAGCGCCACCAGCGTGACCCAGTTGCAGG
ACGTGCTGGCGGCCGGGCAGATCACGCTCAGCGATGCGCAGATCGCGCAGCTCGACGAGGCCAGCGCAGCGGAACCAGCC
GGCGCCTGA

Upstream 100 bases:

>100_bases
GCGGCAGCGCGGTGTGCGGAACGCTGAATCCACACCGATGTCACACGCAACAGCACCGGGCATGACTATCCTGTGGTCAG
TTCGAAACAGGAGCCCTGTG

Downstream 100 bases:

>100_bases
TCCGCATCAGCCACTGCGCCACCGCGCTCGCCATTCACTCACCTCGCGCAGCCGCACGGCGGCTGTGCCCCCACGACCGC
GCCTTGCGCGGTCCCTTCCG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPHSRALGRSGLQVQPIVFGGNVFGWSADEATSFALLDAFVDAGFNMIDTADAYSGWVPGNRGGESETIIGRWLARSGKR
DKVLIATKVAKWSEHPGLSPDNIAAAVEDSLSRLQTDVIDLYQAHEDDESIPLEATLAAFGRLIEQGKVRAIGASNYTAA
RLRDALDVSAQYNLPRYESLQPEYNLYDRAGFEEELEPLVQERGLGVISYYSLASGFLTGKYRSADDAGKSSARGASVVK
QYVNPRGLRILQALDDLAATHTATPAQIALAWLIARPSVTAPIVSATSVTQLQDVLAAGQITLSDAQIAQLDEASAAEPA
GA

Sequences:

>Translated_322_residues
MPHSRALGRSGLQVQPIVFGGNVFGWSADEATSFALLDAFVDAGFNMIDTADAYSGWVPGNRGGESETIIGRWLARSGKR
DKVLIATKVAKWSEHPGLSPDNIAAAVEDSLSRLQTDVIDLYQAHEDDESIPLEATLAAFGRLIEQGKVRAIGASNYTAA
RLRDALDVSAQYNLPRYESLQPEYNLYDRAGFEEELEPLVQERGLGVISYYSLASGFLTGKYRSADDAGKSSARGASVVK
QYVNPRGLRILQALDDLAATHTATPAQIALAWLIARPSVTAPIVSATSVTQLQDVLAAGQITLSDAQIAQLDEASAAEPA
GA
>Mature_321_residues
PHSRALGRSGLQVQPIVFGGNVFGWSADEATSFALLDAFVDAGFNMIDTADAYSGWVPGNRGGESETIIGRWLARSGKRD
KVLIATKVAKWSEHPGLSPDNIAAAVEDSLSRLQTDVIDLYQAHEDDESIPLEATLAAFGRLIEQGKVRAIGASNYTAAR
LRDALDVSAQYNLPRYESLQPEYNLYDRAGFEEELEPLVQERGLGVISYYSLASGFLTGKYRSADDAGKSSARGASVVKQ
YVNPRGLRILQALDDLAATHTATPAQIALAWLIARPSVTAPIVSATSVTQLQDVLAAGQITLSDAQIAQLDEASAAEPAG
A

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=327, Percent_Identity=28.7461773700306, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=28.7461773700306, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=29.2604501607717, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=29.3577981651376, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=28.6644951140065, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436964, Length=327, Percent_Identity=27.5229357798165, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI223718702, Length=216, Percent_Identity=38.4259259259259, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI41327764, Length=217, Percent_Identity=36.8663594470046, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI41152114, Length=216, Percent_Identity=37.5, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI223718708, Length=143, Percent_Identity=40.5594405594406, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=33.7461300309598, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789199, Length=337, Percent_Identity=32.3442136498516, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789375, Length=325, Percent_Identity=28.6153846153846, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=31.629392971246, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788081, Length=293, Percent_Identity=32.0819112627986, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786400, Length=310, Percent_Identity=27.0967741935484, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=310, Percent_Identity=26.1290322580645, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=29.1666666666667, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=27.3273273273273, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=27.8145695364238, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=339, Percent_Identity=26.2536873156342, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321052, Length=163, Percent_Identity=32.5153374233129, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=23.5059760956175, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=27.2463768115942, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI45549126, Length=343, Percent_Identity=27.1137026239067, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24646155, Length=319, Percent_Identity=28.5266457680251, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644950, Length=336, Percent_Identity=25, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646159, Length=265, Percent_Identity=27.5471698113208, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34379; Mature: 34247

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHSRALGRSGLQVQPIVFGGNVFGWSADEATSFALLDAFVDAGFNMIDTADAYSGWVPG
CCCCCCCCCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHCCCCEEECCCHHCCCCCC
NRGGESETIIGRWLARSGKRDKVLIATKVAKWSEHPGLSPDNIAAAVEDSLSRLQTDVID
CCCCCCHHHHHHHHHCCCCCCEEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LYQAHEDDESIPLEATLAAFGRLIEQGKVRAIGASNYTAARLRDALDVSAQYNLPRYESL
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCHHCCCCCCCCCC
QPEYNLYDRAGFEEELEPLVQERGLGVISYYSLASGFLTGKYRSADDAGKSSARGASVVK
CCCCCCHHHCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
QYVNPRGLRILQALDDLAATHTATPAQIALAWLIARPSVTAPIVSATSVTQLQDVLAAGQ
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
ITLSDAQIAQLDEASAAEPAGA
EEECCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PHSRALGRSGLQVQPIVFGGNVFGWSADEATSFALLDAFVDAGFNMIDTADAYSGWVPG
CCCCCCCCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHCCCCEEECCCHHCCCCCC
NRGGESETIIGRWLARSGKRDKVLIATKVAKWSEHPGLSPDNIAAAVEDSLSRLQTDVID
CCCCCCHHHHHHHHHCCCCCCEEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LYQAHEDDESIPLEATLAAFGRLIEQGKVRAIGASNYTAARLRDALDVSAQYNLPRYESL
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCHHCCCCCCCCCC
QPEYNLYDRAGFEEELEPLVQERGLGVISYYSLASGFLTGKYRSADDAGKSSARGASVVK
CCCCCCHHHCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
QYVNPRGLRILQALDDLAATHTATPAQIALAWLIARPSVTAPIVSATSVTQLQDVLAAGQ
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
ITLSDAQIAQLDEASAAEPAGA
EEECCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]