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The map label for this gene is 66766587

Identifier: 66766587

GI number: 66766587

Start: 292774

End: 293826

Strand: Reverse

Name: 66766587

Synonym: XC_0242

Alternate gene names: NA

Gene position: 293826-292774 (Counterclockwise)

Preceding gene: 66766589

Following gene: 77761079

Centisome position: 5.71

GC content: 68.0

Gene sequence:

>1053_bases
GTGCCCCCCCCTTCTTCCGCTTATGCCGCTTCGCCGCAGTTCCGCAATGGCCGGTTTCGCAACGCCCAGCCCACGCTGAC
CACCTCGCTGCGCCTGGGCGAGCAGCTGCGGTTGCTGTGGACGTTCTTCTTCGACAAGCCACGCGACACCGTACCGTCCA
CACCACCGCCGGTGTTGCCGCTGACTCGCGCGCAGCTGCTCGCCGCGCCGGACCGCAGCCTGTACCGGCTTGGCCACTCC
ACCGTGTTGCTGAAGCTGGCCGGCGGTTTCTGGCTCACCGACCCGGTGTTCGCCAAGCGCGCCTCGCCGTTTTCCTTCGC
CGGCCCCAAACGCTTCCATGCCCCGCCGATTGCACTGGCCGACCTGCCGCCGCTGGCCGGGGTGATCCTGTCGCACAACC
ACTACGACCACCTGGACCGCGCCACCATCCGCGCACTGGCCGACCGCGTTGGCGTTTTCGTCGCGCCGCTGGGCGTGGGC
GATTTACTGGTACGTTGGGGCGTGGACCCGGCCAAGGTGCGGCAGCTGGACTGGTGGGACTCGCTCAACGTGGACGGTGT
GCAGCTCACCGCCACGCCATCGCAGCACTTTTCCGGGCGCGGGTTGTTCGATAGCGGCCGCTCGCTGTGGTGCTCGTGGG
TGATCCAGCACGAGGAGCTGCGGGTGTTCTTCAGCGGCGACGGTGGCTACGCGCCGCACTTCAAGACCATCGGTGAGCAG
CTCGGCCCGTTCGATGTGGCGCTGATCGAAAACGGCGCCTACGACCAGCAATGGCCGCATGTGCACATGCAACCGGAGCA
GAGCCTGCAGGCATATCTGGACGTGGGCGGGCAGACGCTGCTGCCGATCCACAACGGCACCTTCGATCTGGCCATGCACG
CCTGGCAGGAGCCGCTGGACCGGATCGTGGCGTTGGCCGATAGCGCCGGCGTTGCGCTGGTCACGCCGTGCATGGGCGAG
CGGGTGGATCTGCAGGCGCCGGCCAATCGCGTGCGTTGGTGGCGGCAGGATGCGGCGGCAGCGGCGTCGGATGGAATGGT
GGTGACGCGGTAA

Upstream 100 bases:

>100_bases
GTGAATGGACATGCGCTGATTTTACACCGGGCAGTTTACTTTCACGTCGCGGAAACTACACTGTGCAGTGTAATCACTTC
CCCGCCGACGGATTCCGCCC

Downstream 100 bases:

>100_bases
CTGGCCTGAGGCATGCCGACGCGTTGCCATGACGTTTTGATGGCACACCTCGCACGCGGATGCGCGCGGCACCCGTCGCC
GCGTGACGCTTCACCAACCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPPPSSAYAASPQFRNGRFRNAQPTLTTSLRLGEQLRLLWTFFFDKPRDTVPSTPPPVLPLTRAQLLAAPDRSLYRLGHS
TVLLKLAGGFWLTDPVFAKRASPFSFAGPKRFHAPPIALADLPPLAGVILSHNHYDHLDRATIRALADRVGVFVAPLGVG
DLLVRWGVDPAKVRQLDWWDSLNVDGVQLTATPSQHFSGRGLFDSGRSLWCSWVIQHEELRVFFSGDGGYAPHFKTIGEQ
LGPFDVALIENGAYDQQWPHVHMQPEQSLQAYLDVGGQTLLPIHNGTFDLAMHAWQEPLDRIVALADSAGVALVTPCMGE
RVDLQAPANRVRWWRQDAAAAASDGMVVTR

Sequences:

>Translated_350_residues
MPPPSSAYAASPQFRNGRFRNAQPTLTTSLRLGEQLRLLWTFFFDKPRDTVPSTPPPVLPLTRAQLLAAPDRSLYRLGHS
TVLLKLAGGFWLTDPVFAKRASPFSFAGPKRFHAPPIALADLPPLAGVILSHNHYDHLDRATIRALADRVGVFVAPLGVG
DLLVRWGVDPAKVRQLDWWDSLNVDGVQLTATPSQHFSGRGLFDSGRSLWCSWVIQHEELRVFFSGDGGYAPHFKTIGEQ
LGPFDVALIENGAYDQQWPHVHMQPEQSLQAYLDVGGQTLLPIHNGTFDLAMHAWQEPLDRIVALADSAGVALVTPCMGE
RVDLQAPANRVRWWRQDAAAAASDGMVVTR
>Mature_349_residues
PPPSSAYAASPQFRNGRFRNAQPTLTTSLRLGEQLRLLWTFFFDKPRDTVPSTPPPVLPLTRAQLLAAPDRSLYRLGHST
VLLKLAGGFWLTDPVFAKRASPFSFAGPKRFHAPPIALADLPPLAGVILSHNHYDHLDRATIRALADRVGVFVAPLGVGD
LLVRWGVDPAKVRQLDWWDSLNVDGVQLTATPSQHFSGRGLFDSGRSLWCSWVIQHEELRVFFSGDGGYAPHFKTIGEQL
GPFDVALIENGAYDQQWPHVHMQPEQSLQAYLDVGGQTLLPIHNGTFDLAMHAWQEPLDRIVALADSAGVALVTPCMGER
VDLQAPANRVRWWRQDAAAAASDGMVVTR

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=309, Percent_Identity=37.2168284789644, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI170932481, Length=309, Percent_Identity=37.2168284789644, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17543102, Length=282, Percent_Identity=36.5248226950355, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17543100, Length=282, Percent_Identity=36.5248226950355, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI25148824, Length=282, Percent_Identity=36.5248226950355, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17543104, Length=262, Percent_Identity=37.4045801526718, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6325154, Length=251, Percent_Identity=31.0756972111554, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38627; Mature: 38496

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPPSSAYAASPQFRNGRFRNAQPTLTTSLRLGEQLRLLWTFFFDKPRDTVPSTPPPVLP
CCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LTRAQLLAAPDRSLYRLGHSTVLLKLAGGFWLTDPVFAKRASPFSFAGPKRFHAPPIALA
CCHHHHHHCCCHHHHHHCCCEEEEEEECCCEECCHHHHHCCCCCCCCCCCCCCCCCEECC
DLPPLAGVILSHNHYDHLDRATIRALADRVGVFVAPLGVGDLLVRWGVDPAKVRQLDWWD
CCCCHHHHEECCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHCCCCHHHHEEECCCC
SLNVDGVQLTATPSQHFSGRGLFDSGRSLWCSWVIQHEELRVFFSGDGGYAPHFKTIGEQ
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
LGPFDVALIENGAYDQQWPHVHMQPEQSLQAYLDVGGQTLLPIHNGTFDLAMHAWQEPLD
CCCEEEEEEECCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
RIVALADSAGVALVTPCMGERVDLQAPANRVRWWRQDAAAAASDGMVVTR
HHHHHHCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
PPPSSAYAASPQFRNGRFRNAQPTLTTSLRLGEQLRLLWTFFFDKPRDTVPSTPPPVLP
CCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LTRAQLLAAPDRSLYRLGHSTVLLKLAGGFWLTDPVFAKRASPFSFAGPKRFHAPPIALA
CCHHHHHHCCCHHHHHHCCCEEEEEEECCCEECCHHHHHCCCCCCCCCCCCCCCCCEECC
DLPPLAGVILSHNHYDHLDRATIRALADRVGVFVAPLGVGDLLVRWGVDPAKVRQLDWWD
CCCCHHHHEECCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHCCCCHHHHEEECCCC
SLNVDGVQLTATPSQHFSGRGLFDSGRSLWCSWVIQHEELRVFFSGDGGYAPHFKTIGEQ
CCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
LGPFDVALIENGAYDQQWPHVHMQPEQSLQAYLDVGGQTLLPIHNGTFDLAMHAWQEPLD
CCCEEEEEEECCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
RIVALADSAGVALVTPCMGERVDLQAPANRVRWWRQDAAAAASDGMVVTR
HHHHHHCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]