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The map label for this gene is yeaD [H]

Identifier: 66048268

GI number: 66048268

Start: 5986112

End: 5987023

Strand: Direct

Name: yeaD [H]

Synonym: Psyr_5044

Alternate gene names: 66048268

Gene position: 5986112-5987023 (Clockwise)

Preceding gene: 66048267

Following gene: 66048273

Centisome position: 98.23

GC content: 60.96

Gene sequence:

>912_bases
ATGCCAACATCCCCGGTTGAACCCACCGTTGAATCCATCCTTTACGATGAGCTGAACTGCTGGCGTATTTGCCACGGCGA
AGCAGAGCTGCTGGTTGCGCAACAAGGCGCACACATCCTCAGCTATCAAGTGGCCGGGCAGCAGCCGCTGGTGTGGCTGA
ACGAAGAGGCGGTTTTCAAACGCGGCAAACCCATTCGTGCCGGCATGCCGATCTGCTGGCCGTGGTTCGGTAACCTGGAG
CGCAACCCGCAAAGCGTGCAGGCAATGCGCGACAGCAGCGAACCTGCCAAGGCGCATGGCGAAGTGCGGGCGCTGGACTG
GCAGTTGCTGGGTATTGGCGCAGATGGCGACGCACTGCTGGTGGAGTTCGTGCTTCCCGAAGCCGAAGGCCACTTGCCTG
GCTGGCCGCACAACGTCGCCCTGAAACTGAGCATTCGTCTGGACCACGCACTGAATGTCAGTCTGGTCAGCTACAACTGC
GGCACTGAGCCAGTAGTGATCAGCCAGGCACTGCACACCTATTTCGCCGTTAGCGACGTACGTCAGGTCAGTGTCGAAGG
GCTCGACGGCCTGCGTTACATCGAAACCCTGGCAAACTGGGAAGAACGCGAGCAGAGCGGCGACCTGACCTTCACAGGCG
AAACCGACCGCATCTACAAGGACACGCCGGGCGTGCTCAGCATCGTTGACCCCGAGTGGCAGCGACGCATCCACATCCGC
AGCACGGGCTCGAACTCAGCCATCCTGTGGAACCCGTGGATCGAAAAGACCGGCAAGTTCACCGACATGGCAGCAGACGG
CTGGCAGCGCATGGTCTGCGTCGAAACCGCCAACGTGCTGGACGACGTGGTCACGCTGGCACCGGACCAGATGCATGTGC
TGGGTGTGAGTATCTGGAGCGAAGCGCTCTGA

Upstream 100 bases:

>100_bases
CGACGGTAAATTGTCGTTCGGTCATGGATTGGCTGCACGGGTAAACTCACCGAGCGTGAAGCGGTCTATTTTCGTCACGG
TCATTGAGTGAGAACTTTGC

Downstream 100 bases:

>100_bases
TCGATCAGTAATCGATCAAGCCCATCAAAGGTCCGACTCAACCACCACACGGACCTTTGACGCGTCCATCGCATACGCCG
CATCGGCAAGGTCATTACTG

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPTSPVEPTVESILYDELNCWRICHGEAELLVAQQGAHILSYQVAGQQPLVWLNEEAVFKRGKPIRAGMPICWPWFGNLE
RNPQSVQAMRDSSEPAKAHGEVRALDWQLLGIGADGDALLVEFVLPEAEGHLPGWPHNVALKLSIRLDHALNVSLVSYNC
GTEPVVISQALHTYFAVSDVRQVSVEGLDGLRYIETLANWEEREQSGDLTFTGETDRIYKDTPGVLSIVDPEWQRRIHIR
STGSNSAILWNPWIEKTGKFTDMAADGWQRMVCVETANVLDDVVTLAPDQMHVLGVSIWSEAL

Sequences:

>Translated_303_residues
MPTSPVEPTVESILYDELNCWRICHGEAELLVAQQGAHILSYQVAGQQPLVWLNEEAVFKRGKPIRAGMPICWPWFGNLE
RNPQSVQAMRDSSEPAKAHGEVRALDWQLLGIGADGDALLVEFVLPEAEGHLPGWPHNVALKLSIRLDHALNVSLVSYNC
GTEPVVISQALHTYFAVSDVRQVSVEGLDGLRYIETLANWEEREQSGDLTFTGETDRIYKDTPGVLSIVDPEWQRRIHIR
STGSNSAILWNPWIEKTGKFTDMAADGWQRMVCVETANVLDDVVTLAPDQMHVLGVSIWSEAL
>Mature_302_residues
PTSPVEPTVESILYDELNCWRICHGEAELLVAQQGAHILSYQVAGQQPLVWLNEEAVFKRGKPIRAGMPICWPWFGNLER
NPQSVQAMRDSSEPAKAHGEVRALDWQLLGIGADGDALLVEFVLPEAEGHLPGWPHNVALKLSIRLDHALNVSLVSYNCG
TEPVVISQALHTYFAVSDVRQVSVEGLDGLRYIETLANWEEREQSGDLTFTGETDRIYKDTPGVLSIVDPEWQRRIHIRS
TGSNSAILWNPWIEKTGKFTDMAADGWQRMVCVETANVLDDVVTLAPDQMHVLGVSIWSEAL

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=273, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6323746, Length=271, Percent_Identity=27.6752767527675, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19921284, Length=260, Percent_Identity=28.8461538461538, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28574481, Length=154, Percent_Identity=30.5194805194805, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 33773; Mature: 33641

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSPVEPTVESILYDELNCWRICHGEAELLVAQQGAHILSYQVAGQQPLVWLNEEAVFK
CCCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEECCCEEEEEEECCCCCEEEECCHHHHH
RGKPIRAGMPICWPWFGNLERNPQSVQAMRDSSEPAKAHGEVRALDWQLLGIGADGDALL
CCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCHHCCCEEEEEEEEEEECCCCCEEE
VEFVLPEAEGHLPGWPHNVALKLSIRLDHALNVSLVSYNCGTEPVVISQALHTYFAVSDV
EEEEECCCCCCCCCCCCCEEEEEEEEECCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHH
RQVSVEGLDGLRYIETLANWEEREQSGDLTFTGETDRIYKDTPGVLSIVDPEWQRRIHIR
HHHHHCCCCHHHHHHHHHCHHHHHCCCCEEEECCCCCEECCCCCEEEEECCCHHCEEEEE
STGSNSAILWNPWIEKTGKFTDMAADGWQRMVCVETANVLDDVVTLAPDQMHVLGVSIWS
ECCCCCEEEECCHHHCCCCEEECCCCCHHEEEEEHHHHHHHHHHHCCCCCEEEEEEEHHH
EAL
HCC
>Mature Secondary Structure 
PTSPVEPTVESILYDELNCWRICHGEAELLVAQQGAHILSYQVAGQQPLVWLNEEAVFK
CCCCCCHHHHHHHHHCCCEEEEECCCEEEEEEECCCEEEEEEECCCCCEEEECCHHHHH
RGKPIRAGMPICWPWFGNLERNPQSVQAMRDSSEPAKAHGEVRALDWQLLGIGADGDALL
CCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCHHCCCEEEEEEEEEEECCCCCEEE
VEFVLPEAEGHLPGWPHNVALKLSIRLDHALNVSLVSYNCGTEPVVISQALHTYFAVSDV
EEEEECCCCCCCCCCCCCEEEEEEEEECCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHH
RQVSVEGLDGLRYIETLANWEEREQSGDLTFTGETDRIYKDTPGVLSIVDPEWQRRIHIR
HHHHHCCCCHHHHHHHHHCHHHHHCCCCEEEECCCCCEECCCCCEEEEECCCHHCEEEEE
STGSNSAILWNPWIEKTGKFTDMAADGWQRMVCVETANVLDDVVTLAPDQMHVLGVSIWS
ECCCCCEEEECCHHHCCCCEEECCCCCHHEEEEEHHHHHHHHHHHCCCCCEEEEEEEHHH
EAL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]