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The map label for this gene is ubiA [H]

Identifier: 66048255

GI number: 66048255

Start: 5969964

End: 5970854

Strand: Direct

Name: ubiA [H]

Synonym: Psyr_5031

Alternate gene names: 66048255

Gene position: 5969964-5970854 (Clockwise)

Preceding gene: 66048254

Following gene: 66048256

Centisome position: 97.97

GC content: 63.64

Gene sequence:

>891_bases
ATGTACCTGTCCCTCCTCAAATCCCTCAATCGTCTGAGCCCGCGCGCCTGGGACTTCATCCAGCTGACGCGCATCGACAA
GCCCATCGGCGTCTACCTGCTGCTGTGGCCGACCCTGTGGGCGGTCTGGATTGCAGGCAAAGGCGCGCCGTCGCTGCAGA
CCGTGTGCATTTTTGTGCTCGGCGTCTTTCTGATGCGCGCGGCAGGCTGTGTGATCAATGACTTCGCCGACCGCAAGGTG
GATGGCCACGTCAAACGCACCGAGCAGCGTCCGCTGGTCAGCGGCAAAGTCAGCCCCCGGGAAGCGCTGGTGCTGTTTGC
GGTGCTGGTCGGCCTGAGCTTTGTGCTGGTGCTGTTCACCAACGCGGCGACTATCTGGCTGTCGTTCGGCGGTCTCGCCC
TGGCGGCCAGCTATCCGTTCATGAAGCGCTACACCTATTACCCGCAAGTGGTGCTGGGGGCTGCGTTCTCGTGGGGCATG
CCGATGGCCTTCACTGCCGAAACCGGAGAGCTGCCCGCTGCAGCCTGGCTGCTGTACATCGCCAACCTGCTGTGGACCGT
GGGCTACGACACCTACTACGCCATGGTCGATCGCGACGACGACCTGAAAATCGGCGTGAAATCCACGGCCGTCCTGTTCG
GCGATGCCGACCGGGTCATCATCCTGACCCTGCAAGGGCTGGCACTGGGCTGCCTGATGCTGGCCGGTGCGCGCTTCGAA
CTGGGCGCGTGTTTCTACATCGGTCTGCTGGCAGCGGCAGGCTGCTTTGCCTGGGAATTCTGGAGCACCCGAGAGCGCGA
GCGAGACGCCTGCTTCAAGGCCTTCCTGCACAATCACTGGGCCGGGCTGGCGATATTCCTGGGCATCGTCGCCGACTACG
CGGTGCGCTGA

Upstream 100 bases:

>100_bases
CACGGCGCTCGCGCTTTGATCGCGATGCCTTGAGCGTGCTGGTCGCCGAAGTTTTCCTGCCTGCCCTGTGCACTGCGATT
CATGACAAGGACCACGTCTG

Downstream 100 bases:

>100_bases
AAACAGCCAGCGCCAGCCTGGGCACGAATTAAATAACTTCAGGATCGCGGGGCCTGCGGGCCCCCGCAGCCTGTCAGCGT
GCTAGCCTCATTCAGACCTG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MYLSLLKSLNRLSPRAWDFIQLTRIDKPIGVYLLLWPTLWAVWIAGKGAPSLQTVCIFVLGVFLMRAAGCVINDFADRKV
DGHVKRTEQRPLVSGKVSPREALVLFAVLVGLSFVLVLFTNAATIWLSFGGLALAASYPFMKRYTYYPQVVLGAAFSWGM
PMAFTAETGELPAAAWLLYIANLLWTVGYDTYYAMVDRDDDLKIGVKSTAVLFGDADRVIILTLQGLALGCLMLAGARFE
LGACFYIGLLAAAGCFAWEFWSTRERERDACFKAFLHNHWAGLAIFLGIVADYAVR

Sequences:

>Translated_296_residues
MYLSLLKSLNRLSPRAWDFIQLTRIDKPIGVYLLLWPTLWAVWIAGKGAPSLQTVCIFVLGVFLMRAAGCVINDFADRKV
DGHVKRTEQRPLVSGKVSPREALVLFAVLVGLSFVLVLFTNAATIWLSFGGLALAASYPFMKRYTYYPQVVLGAAFSWGM
PMAFTAETGELPAAAWLLYIANLLWTVGYDTYYAMVDRDDDLKIGVKSTAVLFGDADRVIILTLQGLALGCLMLAGARFE
LGACFYIGLLAAAGCFAWEFWSTRERERDACFKAFLHNHWAGLAIFLGIVADYAVR
>Mature_296_residues
MYLSLLKSLNRLSPRAWDFIQLTRIDKPIGVYLLLWPTLWAVWIAGKGAPSLQTVCIFVLGVFLMRAAGCVINDFADRKV
DGHVKRTEQRPLVSGKVSPREALVLFAVLVGLSFVLVLFTNAATIWLSFGGLALAASYPFMKRYTYYPQVVLGAAFSWGM
PMAFTAETGELPAAAWLLYIANLLWTVGYDTYYAMVDRDDDLKIGVKSTAVLFGDADRVIILTLQGLALGCLMLAGARFE
LGACFYIGLLAAAGCFAWEFWSTRERERDACFKAFLHNHWAGLAIFLGIVADYAVR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=275, Percent_Identity=35.2727272727273, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=56.7272727272727, Blast_Score=297, Evalue=4e-82,
Organism=Escherichia coli, GI1786631, Length=225, Percent_Identity=28.8888888888889, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17553718, Length=283, Percent_Identity=37.8091872791519, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32565247, Length=288, Percent_Identity=37.5, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17553720, Length=339, Percent_Identity=31.2684365781711, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32565245, Length=142, Percent_Identity=41.5492957746479, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=141, Percent_Identity=41.1347517730496, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=295, Percent_Identity=35.2542372881356, Blast_Score=163, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21355567, Length=285, Percent_Identity=38.5964912280702, Blast_Score=197, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32808; Mature: 32808

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLSLLKSLNRLSPRAWDFIQLTRIDKPIGVYLLLWPTLWAVWIAGKGAPSLQTVCIFVL
CHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GVFLMRAAGCVINDFADRKVDGHVKRTEQRPLVSGKVSPREALVLFAVLVGLSFVLVLFT
HHHHHHHCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAATIWLSFGGLALAASYPFMKRYTYYPQVVLGAAFSWGMPMAFTAETGELPAAAWLLYI
CHHHEEEECCCHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHH
ANLLWTVGYDTYYAMVDRDDDLKIGVKSTAVLFGDADRVIILTLQGLALGCLMLAGARFE
HHHHHHHCCCEEEEEEECCCCCEEEECEEEEEECCCCCEEEEEECHHHHHHHHHHCCCCH
LGACFYIGLLAAAGCFAWEFWSTRERERDACFKAFLHNHWAGLAIFLGIVADYAVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYLSLLKSLNRLSPRAWDFIQLTRIDKPIGVYLLLWPTLWAVWIAGKGAPSLQTVCIFVL
CHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GVFLMRAAGCVINDFADRKVDGHVKRTEQRPLVSGKVSPREALVLFAVLVGLSFVLVLFT
HHHHHHHCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAATIWLSFGGLALAASYPFMKRYTYYPQVVLGAAFSWGMPMAFTAETGELPAAAWLLYI
CHHHEEEECCCHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHH
ANLLWTVGYDTYYAMVDRDDDLKIGVKSTAVLFGDADRVIILTLQGLALGCLMLAGARFE
HHHHHHHCCCEEEEEEECCCCCEEEECEEEEEECCCCCEEEEEECHHHHHHHHHHCCCCH
LGACFYIGLLAAAGCFAWEFWSTRERERDACFKAFLHNHWAGLAIFLGIVADYAVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA