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The map label for this gene is ubiC

Identifier: 66048254

GI number: 66048254

Start: 5969404

End: 5969964

Strand: Direct

Name: ubiC

Synonym: Psyr_5030

Alternate gene names: 66048254

Gene position: 5969404-5969964 (Clockwise)

Preceding gene: 66048248

Following gene: 66048255

Centisome position: 97.96

GC content: 63.81

Gene sequence:

>561_bases
GTGACCCAGCAATCCCCCGCATTCATTGGCCCTGCCTGGCTTGAGCGCGAGCAATTGATCGACGCACCGGACCCGGTAAT
GCTCGACTGGTTGTTCAATCAGGACTCCCTCACTCGTCGGTTGGACCGTTTGTCTGACGGTCGTTTCAGCGTATTTCCGC
AGTTTGAAGGCTGGCAGCCCTTGCGCCCTGACGAGTGCCTGGCGCTGGGCCTGCCAGAGGCTGGCGAAGGCTGGGTGCGC
GAGGTGTACCTGCGTGGTAACGGCAACAACTGGGTGTTCGCGCGCAGTGTCGCCGCCCGCAGCGCCCTGCAGGATGGTGG
CCTGGATATGGACGAGCTGGGCACTCGCTCGCTGGGTGAGTTGCTGTTCAGCGACCCGGCGTTCGTGCGCGGCACGCTTG
AAGTGTGTCATTACCCCGAGGCCTGGCTGCCGGCTGCCGATGCAGCGCGCGGACTGTGGGCACGGCGCTCGCGCTTTGAT
CGCGATGCCTTGAGCGTGCTGGTCGCCGAAGTTTTCCTGCCTGCCCTGTGCACTGCGATTCATGACAAGGACCACGTCTG
A

Upstream 100 bases:

>100_bases
TGCAAGTCTGATTCTATAACCCGACGCTCTATCGACCGTCGGTCGAGACCGGCAATCATGCTAAGCTCGCGGCCTCGTTG
GCTGCCGGAACTGGCTTACC

Downstream 100 bases:

>100_bases
TGTACCTGTCCCTCCTCAAATCCCTCAATCGTCTGAGCCCGCGCGCCTGGGACTTCATCCAGCTGACGCGCATCGACAAG
CCCATCGGCGTCTACCTGCT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTQQSPAFIGPAWLEREQLIDAPDPVMLDWLFNQDSLTRRLDRLSDGRFSVFPQFEGWQPLRPDECLALGLPEAGEGWVR
EVYLRGNGNNWVFARSVAARSALQDGGLDMDELGTRSLGELLFSDPAFVRGTLEVCHYPEAWLPAADAARGLWARRSRFD
RDALSVLVAEVFLPALCTAIHDKDHV

Sequences:

>Translated_186_residues
MTQQSPAFIGPAWLEREQLIDAPDPVMLDWLFNQDSLTRRLDRLSDGRFSVFPQFEGWQPLRPDECLALGLPEAGEGWVR
EVYLRGNGNNWVFARSVAARSALQDGGLDMDELGTRSLGELLFSDPAFVRGTLEVCHYPEAWLPAADAARGLWARRSRFD
RDALSVLVAEVFLPALCTAIHDKDHV
>Mature_185_residues
TQQSPAFIGPAWLEREQLIDAPDPVMLDWLFNQDSLTRRLDRLSDGRFSVFPQFEGWQPLRPDECLALGLPEAGEGWVRE
VYLRGNGNNWVFARSVAARSALQDGGLDMDELGTRSLGELLFSDPAFVRGTLEVCHYPEAWLPAADAARGLWARRSRFDR
DALSVLVAEVFLPALCTAIHDKDHV

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=158, Percent_Identity=36.0759493670886, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_PSEU2 (Q4ZLB5)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_238095.1
- ProteinModelPortal:   Q4ZLB5
- SMR:   Q4ZLB5
- STRING:   Q4ZLB5
- GeneID:   3370588
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_5030
- NMPDR:   fig|205918.4.peg.230
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   EVCHYPE
- ProtClustDB:   CLSK869287
- BioCyc:   PSYR205918:PSYR_5030-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 20882; Mature: 20751

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: BINDING 80-80 BINDING 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQSPAFIGPAWLEREQLIDAPDPVMLDWLFNQDSLTRRLDRLSDGRFSVFPQFEGWQP
CCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCC
LRPDECLALGLPEAGEGWVREVYLRGNGNNWVFARSVAARSALQDGGLDMDELGTRSLGE
CCCCCEEEECCCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHHHCCCCCHHHHCHHHHHH
LLFSDPAFVRGTLEVCHYPEAWLPAADAARGLWARRSRFDRDALSVLVAEVFLPALCTAI
HHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HDKDHV
HCCCCC
>Mature Secondary Structure 
TQQSPAFIGPAWLEREQLIDAPDPVMLDWLFNQDSLTRRLDRLSDGRFSVFPQFEGWQP
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCC
LRPDECLALGLPEAGEGWVREVYLRGNGNNWVFARSVAARSALQDGGLDMDELGTRSLGE
CCCCCEEEECCCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHHHCCCCCHHHHCHHHHHH
LLFSDPAFVRGTLEVCHYPEAWLPAADAARGLWARRSRFDRDALSVLVAEVFLPALCTAI
HHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HDKDHV
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA