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The map label for this gene is cat1 [H]

Identifier: 66048243

GI number: 66048243

Start: 5960765

End: 5962258

Strand: Direct

Name: cat1 [H]

Synonym: Psyr_5019

Alternate gene names: 66048243

Gene position: 5960765-5962258 (Clockwise)

Preceding gene: 66048242

Following gene: 66048244

Centisome position: 97.82

GC content: 61.11

Gene sequence:

>1494_bases
ATGTACCGTGACCGTATCCGCCGGCCCTCCCTGATGAGCAAGGTTATGAGCGCAGCCGACGCTGCCGCCTTGATTGAAGA
CGGCATGACCGTCGGCATGAGTGGCTTCACCCGTGCAGGCGAAGCCAAGGCCGTACCCCACGCGCTGGCCGAGCGCGCCA
AAGTGACGCCGCTGAAAATCAGTCTGATGACCGGCGCCAGTCTGGGCAATGACCTGGACAAGCAACTGACCGAGTCCGGC
GTTCTGTCCCGGCGCATGCCCTTTCAGGTCGACAGCACGCTGCGCAAGGCGATCAACAACGGCACGGTGATGTTCATCGA
TCAGCATTTGTCCGACACCGTCGAGCTGCTGCGCAATCGGCAGATCAAGGCTGTGGACCTGGCCGTGATCGAATGCGTGG
CGATCACCGAAGAGGGTCATCTGGTGCTGAGTACCTCCGTGGGCAACTCGGCCAGCTTCGCCATTCTGGCCAAACAGGTC
ATCGTGGAAATCAACCTGTCCCAGCCACTTGAGCTGGAAGGCCTGCACGACATCTATATACCCAGCTACAGACCGACACG
CCTGCCGATTCCGGTCCTGGAGGCCGATTCGCGTATCGGCAGCCACGCGGTGAAGATCGACCCGGCAAAAATAGTCGGCA
TTGTCATCAGCAACCAGCCTGACTCGCCCTCCACGGTCACACCACCTGATGCGGACACGCAGGCCATCGCCAATCATCTG
GTGGAGTTCTTCAAGAAAGAAGTGCGCGAAGACCGGCTGACCGACAAGCTGATGCCACTGCAGGCCGGGATCGGCAACAT
TGCCAACGCCGTGATGCACGGCCTGCTGGCGTCGCCCTTCACGGACCTGACGATGTACTCCGAGGTGCTGCAGGACTCGA
CCTTCGACCTGTTCGATGCAGGCAAACTGACTTTCGCCTCGGGCAGCTCCATGACCTTGTCGGCGGCCAAGCACGCCGAG
GTCTTTGCCGACTTCAATCGTTACAAGTCCAGGCTGGTGTTGCGCCCCCAGGAAATCTCCAACCACCCCGAGGTGATCCG
CCGTCTGGGCATCATCGGGATCAATACCGCGCTGGAGTTCGACCTGTACGGCAATGTGAACTCCACCCACATCTGCGGGA
CACGCATGATGAACGGCATCGGCGGTTCCGGAGACTTCTCGCGCAACGCGCACCTGGCGATCTTCGTCACCAAATCGATC
GCCAAAGGTGGCGCGATATCCAGCGTCGTGCCCATGGTCAGCCATGTCGACCACACCGAACACGACGTCGACATCCTGGT
CACCGAGCAGGGCCTGGCGGATCTGCGCGGCCTGGCGCCTCGCGAGCGCGCCAGGGTGATCATCGACAACTGCGTGCATC
CGGATTATCGCGACGCGCTGAACGCCTATTTAAGTGCTGCTTGCGCTGTGGGCGGGCACACCCCGCACATCCTGCGCGAA
GCACTGAGTTGGCACATCAACCTGGAAGAAACCGGGCGCATGTTGCCAGCCTGA

Upstream 100 bases:

>100_bases
GAACCCGCCAATCAGAGCGCTCAAATGCGACCTTGGTAGCAGGACGAAGCCCGTCCAAGGCTCTAGACTTGTCGTTCGCT
TCTATCTACGAGACAGACCC

Downstream 100 bases:

>100_bases
ACAGGACAGTTGGAAGTGAGCAAGCGCTTTTCTGATTCACTTTCAGCTGGCACCCAAGGGCTTATGAAAAAACTGTACTG
CTGTACCGGTCATAAAACTG

Product: Acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MYRDRIRRPSLMSKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKISLMTGASLGNDLDKQLTESG
VLSRRMPFQVDSTLRKAINNGTVMFIDQHLSDTVELLRNRQIKAVDLAVIECVAITEEGHLVLSTSVGNSASFAILAKQV
IVEINLSQPLELEGLHDIYIPSYRPTRLPIPVLEADSRIGSHAVKIDPAKIVGIVISNQPDSPSTVTPPDADTQAIANHL
VEFFKKEVREDRLTDKLMPLQAGIGNIANAVMHGLLASPFTDLTMYSEVLQDSTFDLFDAGKLTFASGSSMTLSAAKHAE
VFADFNRYKSRLVLRPQEISNHPEVIRRLGIIGINTALEFDLYGNVNSTHICGTRMMNGIGGSGDFSRNAHLAIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEQGLADLRGLAPRERARVIIDNCVHPDYRDALNAYLSAACAVGGHTPHILRE
ALSWHINLEETGRMLPA

Sequences:

>Translated_497_residues
MYRDRIRRPSLMSKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKISLMTGASLGNDLDKQLTESG
VLSRRMPFQVDSTLRKAINNGTVMFIDQHLSDTVELLRNRQIKAVDLAVIECVAITEEGHLVLSTSVGNSASFAILAKQV
IVEINLSQPLELEGLHDIYIPSYRPTRLPIPVLEADSRIGSHAVKIDPAKIVGIVISNQPDSPSTVTPPDADTQAIANHL
VEFFKKEVREDRLTDKLMPLQAGIGNIANAVMHGLLASPFTDLTMYSEVLQDSTFDLFDAGKLTFASGSSMTLSAAKHAE
VFADFNRYKSRLVLRPQEISNHPEVIRRLGIIGINTALEFDLYGNVNSTHICGTRMMNGIGGSGDFSRNAHLAIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEQGLADLRGLAPRERARVIIDNCVHPDYRDALNAYLSAACAVGGHTPHILRE
ALSWHINLEETGRMLPA
>Mature_497_residues
MYRDRIRRPSLMSKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKISLMTGASLGNDLDKQLTESG
VLSRRMPFQVDSTLRKAINNGTVMFIDQHLSDTVELLRNRQIKAVDLAVIECVAITEEGHLVLSTSVGNSASFAILAKQV
IVEINLSQPLELEGLHDIYIPSYRPTRLPIPVLEADSRIGSHAVKIDPAKIVGIVISNQPDSPSTVTPPDADTQAIANHL
VEFFKKEVREDRLTDKLMPLQAGIGNIANAVMHGLLASPFTDLTMYSEVLQDSTFDLFDAGKLTFASGSSMTLSAAKHAE
VFADFNRYKSRLVLRPQEISNHPEVIRRLGIIGINTALEFDLYGNVNSTHICGTRMMNGIGGSGDFSRNAHLAIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEQGLADLRGLAPRERARVIIDNCVHPDYRDALNAYLSAACAVGGHTPHILRE
ALSWHINLEETGRMLPA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=46.5020576131687, Blast_Score=436, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI32563853, Length=226, Percent_Identity=29.646017699115, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538151, Length=384, Percent_Identity=24.7395833333333, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=514, Percent_Identity=44.1634241245136, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 53945; Mature: 53945

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRDRIRRPSLMSKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKI
CCCHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCCEEEE
SLMTGASLGNDLDKQLTESGVLSRRMPFQVDSTLRKAINNGTVMFIDQHLSDTVELLRNR
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCC
QIKAVDLAVIECVAITEEGHLVLSTSVGNSASFAILAKQVIVEINLSQPLELEGLHDIYI
CCEEEHHEEEEEEEEECCCCEEEEECCCCCCHHHHEEEEHEEEECCCCCCCCCCCCEEEC
PSYRPTRLPIPVLEADSRIGSHAVKIDPAKIVGIVISNQPDSPSTVTPPDADTQAIANHL
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
VEFFKKEVREDRLTDKLMPLQAGIGNIANAVMHGLLASPFTDLTMYSEVLQDSTFDLFDA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
GKLTFASGSSMTLSAAKHAEVFADFNRYKSRLVLRPQEISNHPEVIRRLGIIGINTALEF
CCEEEECCCCEEEHHHHHHHHHHHHHHHHHEEEECHHHHCCCHHHHHHHCCEEECCEEEE
DLYGNVNSTHICGTRMMNGIGGSGDFSRNAHLAIFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCEEEHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEQGLADLRGLAPRERARVIIDNCVHPDYRDALNAYLSAACAVGGHTPHILRE
CCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHINLEETGRMLPA
HHHEECCHHHCCCCCCC
>Mature Secondary Structure
MYRDRIRRPSLMSKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKI
CCCHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCCEEEE
SLMTGASLGNDLDKQLTESGVLSRRMPFQVDSTLRKAINNGTVMFIDQHLSDTVELLRNR
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCC
QIKAVDLAVIECVAITEEGHLVLSTSVGNSASFAILAKQVIVEINLSQPLELEGLHDIYI
CCEEEHHEEEEEEEEECCCCEEEEECCCCCCHHHHEEEEHEEEECCCCCCCCCCCCEEEC
PSYRPTRLPIPVLEADSRIGSHAVKIDPAKIVGIVISNQPDSPSTVTPPDADTQAIANHL
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
VEFFKKEVREDRLTDKLMPLQAGIGNIANAVMHGLLASPFTDLTMYSEVLQDSTFDLFDA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
GKLTFASGSSMTLSAAKHAEVFADFNRYKSRLVLRPQEISNHPEVIRRLGIIGINTALEF
CCEEEECCCCEEEHHHHHHHHHHHHHHHHHEEEECHHHHCCCHHHHHHHCCEEECCEEEE
DLYGNVNSTHICGTRMMNGIGGSGDFSRNAHLAIFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCEEEHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCC
HDVDILVTEQGLADLRGLAPRERARVIIDNCVHPDYRDALNAYLSAACAVGGHTPHILRE
CCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHINLEETGRMLPA
HHHEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]