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The map label for this gene is pntB [H]

Identifier: 66048242

GI number: 66048242

Start: 5959131

End: 5960585

Strand: Direct

Name: pntB [H]

Synonym: Psyr_5018

Alternate gene names: 66048242

Gene position: 5959131-5960585 (Clockwise)

Preceding gene: 66048241

Following gene: 66048243

Centisome position: 97.79

GC content: 59.86

Gene sequence:

>1455_bases
ATGAGCATGAATCTGGTTACTCTGCTGTACCTGATCGCATCGATCTGCTTCATCCAGGCACTCAAAGGCTTGTCGCATCC
GACCACCTCGCGCCGTGGCAACCTGTTCGGCATGCTCGGCATGGGCCTGGCGGTCATCACCACAATCGGCCTGGTGTTCA
AGCTCGCGGCACTGTCTAGCGCTGAAGGGACCAGCGCAGGCATCGGCTACATTGTGGTCGGCCTGCTGGTGGGCGGAACC
GCCGGCTCGATCATGGCCAAGCGCGTCGAAATGACCAAAATGCCGGAGCTGGTGGCGTTCATGCACAGCATGATCGGCCT
GGCAGCGGTGTTCATCGCTATAGCAGCCGTGGTCGAGCCTCAATCGCTGGGTATCGTTCGCAATCTGGGCGATGCGATTC
CGGCCGGCAACCGTCTGGAGCTGTTCCTGGGTGCAGCCATCGGTGCGATTACCTTCTCGGGTTCGGTCATCGCTTTCGGC
AAACTCTCGGGCAAGTACAAATTTCGCCTCTTTCAAGGCGCACCGGTACAGTTTGCCGGCCAGCACACGCTCAATCTGGT
CCTGGGTCTGGCCACGCTGTTCTTCGGTCTGACCTTCATGTTCACCGGCAGCCTCACTGCCTTTGCGATCATGCTGGCGC
TGGCCTTTGTCATCGGTGTGTTGCTGATCATCCCGATTGGCGGGGCCGATATGCCGGTGGTGGTCTCGATGCTCAACAGC
TATTCAGGCTGGGCAGCAGCCGGCATCGGCTTTTCGCTGAACAACTCGATGCTGATCATTGCGGGCTCACTGGTAGGCTC
CTCGGGCGCGATCCTTTCCTACATCATGTGCAAGGCGATGAACCGCTCGCTCTTCAACGTGATCGGCGGTGGCTTCGGCG
GCGCAACGGACTCGGCAGGCCCGGCGGGTGCCAAGGAAGCGCGCCCGGTGAAGTCAGGTTCGGCAGACGACGCAACCTTC
TTGCTGACCAATGCCGATACCGTGATCATCGTGCCCGGCTACGGCCTGGCAGTGGCTCGTGCCCAGCATGCGCTCAAGGA
ACTGACCGAGAAGCTCGTCCACCGCGGCGTCACTGTGAAGTACGCCATTCACCCGGTGGCCGGACGCATGCCGGGGCACA
TGAACGTGCTGCTGGCCGAAGCCGAAGTGCCTTACGACCAGGTCTTCGAGATGGACGACATCAACTCCGAATTCGGTCAG
GCCGATGTGGTGCTGGTGCTCGGCGCCAACGACGTGGTCAACCCGGCCGCCAAGAACGATCCGAAATCCCCTATCGCCGG
GATGCCCATTCTGGAGGCGTTCAAGGCCAAGACCATCATCGTCAACAAACGCTCGATGGCCAGTGGTTACGCAGGTCTGG
ATAACGAATTGTTCTATCTGGATAAAACCATGATGGTGTTCGGAGACGCCAAAAAGGTGATCGAGGACATGGTGAAGGCC
GTCGAAAACGCCTAG

Upstream 100 bases:

>100_bases
TGGCGGCCGTGAATGTGTTTGGCGGGTTTCTCGTCACTCGGCGGATGCTGGAGATGTTCAGGAAAAAGGCCCCCAAGGCA
AAGGATGAGGCGCCCAAGTC

Downstream 100 bases:

>100_bases
CCTCACAGCGCTCCATTGAAGCCCCGGCTCGCTTGGCGACCGGGGCTTTTTACATTCCGCGCAACAGTGTTTTGCGCTGG
AACCCGCCAATCAGAGCGCT

Product: NAD(P) transhydrogenase, beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSMNLVTLLYLIASICFIQALKGLSHPTTSRRGNLFGMLGMGLAVITTIGLVFKLAALSSAEGTSAGIGYIVVGLLVGGT
AGSIMAKRVEMTKMPELVAFMHSMIGLAAVFIAIAAVVEPQSLGIVRNLGDAIPAGNRLELFLGAAIGAITFSGSVIAFG
KLSGKYKFRLFQGAPVQFAGQHTLNLVLGLATLFFGLTFMFTGSLTAFAIMLALAFVIGVLLIIPIGGADMPVVVSMLNS
YSGWAAAGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSLFNVIGGGFGGATDSAGPAGAKEARPVKSGSADDATF
LLTNADTVIIVPGYGLAVARAQHALKELTEKLVHRGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMDDINSEFGQ
ADVVLVLGANDVVNPAAKNDPKSPIAGMPILEAFKAKTIIVNKRSMASGYAGLDNELFYLDKTMMVFGDAKKVIEDMVKA
VENA

Sequences:

>Translated_484_residues
MSMNLVTLLYLIASICFIQALKGLSHPTTSRRGNLFGMLGMGLAVITTIGLVFKLAALSSAEGTSAGIGYIVVGLLVGGT
AGSIMAKRVEMTKMPELVAFMHSMIGLAAVFIAIAAVVEPQSLGIVRNLGDAIPAGNRLELFLGAAIGAITFSGSVIAFG
KLSGKYKFRLFQGAPVQFAGQHTLNLVLGLATLFFGLTFMFTGSLTAFAIMLALAFVIGVLLIIPIGGADMPVVVSMLNS
YSGWAAAGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSLFNVIGGGFGGATDSAGPAGAKEARPVKSGSADDATF
LLTNADTVIIVPGYGLAVARAQHALKELTEKLVHRGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMDDINSEFGQ
ADVVLVLGANDVVNPAAKNDPKSPIAGMPILEAFKAKTIIVNKRSMASGYAGLDNELFYLDKTMMVFGDAKKVIEDMVKA
VENA
>Mature_483_residues
SMNLVTLLYLIASICFIQALKGLSHPTTSRRGNLFGMLGMGLAVITTIGLVFKLAALSSAEGTSAGIGYIVVGLLVGGTA
GSIMAKRVEMTKMPELVAFMHSMIGLAAVFIAIAAVVEPQSLGIVRNLGDAIPAGNRLELFLGAAIGAITFSGSVIAFGK
LSGKYKFRLFQGAPVQFAGQHTLNLVLGLATLFFGLTFMFTGSLTAFAIMLALAFVIGVLLIIPIGGADMPVVVSMLNSY
SGWAAAGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSLFNVIGGGFGGATDSAGPAGAKEARPVKSGSADDATFL
LTNADTVIIVPGYGLAVARAQHALKELTEKLVHRGVTVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMDDINSEFGQA
DVVLVLGANDVVNPAAKNDPKSPIAGMPILEAFKAKTIIVNKRSMASGYAGLDNELFYLDKTMMVFGDAKKVIEDMVKAV
ENA

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=496, Percent_Identity=44.9596774193548, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI122939153, Length=496, Percent_Identity=44.9596774193548, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI1787886, Length=488, Percent_Identity=51.0245901639344, Blast_Score=459, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI17550456, Length=480, Percent_Identity=43.75, Blast_Score=357, Evalue=1e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50410; Mature: 50279

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNLVTLLYLIASICFIQALKGLSHPTTSRRGNLFGMLGMGLAVITTIGLVFKLAALSS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
AEGTSAGIGYIVVGLLVGGTAGSIMAKRVEMTKMPELVAFMHSMIGLAAVFIAIAAVVEP
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QSLGIVRNLGDAIPAGNRLELFLGAAIGAITFSGSVIAFGKLSGKYKFRLFQGAPVQFAG
HHHHHHHHHHHHCCCCCCEEEEHHHHHHHHEECCCEEEEEECCCEEEEEEEECCCCEECC
QHTLNLVLGLATLFFGLTFMFTGSLTAFAIMLALAFVIGVLLIIPIGGADMPVVVSMLNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
YSGWAAAGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSLFNVIGGGFGGATDSAG
CCCCEEECCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PAGAKEARPVKSGSADDATFLLTNADTVIIVPGYGLAVARAQHALKELTEKLVHRGVTVK
CCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEE
YAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMDDINSEFGQADVVLVLGANDVVNPAAKND
EEEECCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
PKSPIAGMPILEAFKAKTIIVNKRSMASGYAGLDNELFYLDKTMMVFGDAKKVIEDMVKA
CCCCCCCCHHHHHHCCCEEEEECHHHHCCCCCCCCCEEEECCHHHHHCCHHHHHHHHHHH
VENA
HHCC
>Mature Secondary Structure 
SMNLVTLLYLIASICFIQALKGLSHPTTSRRGNLFGMLGMGLAVITTIGLVFKLAALSS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
AEGTSAGIGYIVVGLLVGGTAGSIMAKRVEMTKMPELVAFMHSMIGLAAVFIAIAAVVEP
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QSLGIVRNLGDAIPAGNRLELFLGAAIGAITFSGSVIAFGKLSGKYKFRLFQGAPVQFAG
HHHHHHHHHHHHCCCCCCEEEEHHHHHHHHEECCCEEEEEECCCEEEEEEEECCCCEECC
QHTLNLVLGLATLFFGLTFMFTGSLTAFAIMLALAFVIGVLLIIPIGGADMPVVVSMLNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
YSGWAAAGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSLFNVIGGGFGGATDSAG
CCCCEEECCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PAGAKEARPVKSGSADDATFLLTNADTVIIVPGYGLAVARAQHALKELTEKLVHRGVTVK
CCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEE
YAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMDDINSEFGQADVVLVLGANDVVNPAAKND
EEEECCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
PKSPIAGMPILEAFKAKTIIVNKRSMASGYAGLDNELFYLDKTMMVFGDAKKVIEDMVKA
CCCCCCCCHHHHHHCCCEEEEECHHHHCCCCCCCCCEEEECCHHHHHCCHHHHHHHHHHH
VENA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]