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The map label for this gene is yhcW [H]

Identifier: 66048230

GI number: 66048230

Start: 5938300

End: 5938989

Strand: Direct

Name: yhcW [H]

Synonym: Psyr_5006

Alternate gene names: 66048230

Gene position: 5938300-5938989 (Clockwise)

Preceding gene: 66048228

Following gene: 66048231

Centisome position: 97.45

GC content: 64.35

Gene sequence:

>690_bases
ATGAGCGAGCAGCAAAAACAACGAGGCCCGATCAAGGCCGTCATTTTCGACATGGATGGCCTGTTGCTGGACACCGAGGG
GGTTTACACCGAAGTCACCCACTTGATTGCCAGCCGCCACGGTCGCACCTTCGACTGGTCGGTCAAGCAGCACACCATTG
GCCGCGGTGCCCGGGACTTCTCGGACTACGTGATCAAGGCGCTGGAGCTGCCGATGTCGATCGACGAGTTTCTCGAAGTC
AGGGAGCCCATGCTTGAAGAGCGTTTCCCGCGCGCCGCAGCCATGCCGGGTGCCGAAGCGCTGGTCCGTCATCTGGCTGC
GCATAATATTCCGATCGCCGTGGGCACCAGCTCGTCGGTGCATTACTTCGAGGCCAAGACCACCCTGCACCGCGCGTGGT
TCGAGCTGTTCGACACCGTCGTCACCGCCGACGACCCGGAAGTCGGCGCTGCCAAGCCAGCCCCGGACATCTTTCTGGTC
GCCGCCCGCCGTCTTGGCGTCTCGCCCGCCGATTGCCTGGTCTTCGAAGACTCGCCATTCGGTGTGACCGCCGCCAAGGC
TGCCGGGATGTACGCGGTGGCCGTGCCGGACTCGCACATGCCGGTCGAGCAATACGAGCATGCGGACCTGCTGCTGGGCT
CGCTGGCCGACTTCCCGCTCAAGGCGTGGGGGTTGCCTGAGCTCGCCTGA

Upstream 100 bases:

>100_bases
TGCGCATGCCAATCCCGCTGAAAGGTTTTGAAACAGACCCTAGCCACAGCCTTCCCGGAAACGTTAGGCTGAAACGAATT
TGCGAACAGGACGTGATCAC

Downstream 100 bases:

>100_bases
ATGACATGGAGATGCTGAGCATGAATTATCGAACCCTTGGCCAGTCCGGCCTCAAGGTTTCCACACTGACACTCGGCTCG
ATGATGTTCGGTGAGCAGAC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSEQQKQRGPIKAVIFDMDGLLLDTEGVYTEVTHLIASRHGRTFDWSVKQHTIGRGARDFSDYVIKALELPMSIDEFLEV
REPMLEERFPRAAAMPGAEALVRHLAAHNIPIAVGTSSSVHYFEAKTTLHRAWFELFDTVVTADDPEVGAAKPAPDIFLV
AARRLGVSPADCLVFEDSPFGVTAAKAAGMYAVAVPDSHMPVEQYEHADLLLGSLADFPLKAWGLPELA

Sequences:

>Translated_229_residues
MSEQQKQRGPIKAVIFDMDGLLLDTEGVYTEVTHLIASRHGRTFDWSVKQHTIGRGARDFSDYVIKALELPMSIDEFLEV
REPMLEERFPRAAAMPGAEALVRHLAAHNIPIAVGTSSSVHYFEAKTTLHRAWFELFDTVVTADDPEVGAAKPAPDIFLV
AARRLGVSPADCLVFEDSPFGVTAAKAAGMYAVAVPDSHMPVEQYEHADLLLGSLADFPLKAWGLPELA
>Mature_228_residues
SEQQKQRGPIKAVIFDMDGLLLDTEGVYTEVTHLIASRHGRTFDWSVKQHTIGRGARDFSDYVIKALELPMSIDEFLEVR
EPMLEERFPRAAAMPGAEALVRHLAAHNIPIAVGTSSSVHYFEAKTTLHRAWFELFDTVVTADDPEVGAAKPAPDIFLVA
ARRLGVSPADCLVFEDSPFGVTAAKAAGMYAVAVPDSHMPVEQYEHADLLLGSLADFPLKAWGLPELA

Specific function: Unknown

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=219, Percent_Identity=47.4885844748858, Blast_Score=200, Evalue=9e-52,
Organism=Homo sapiens, GI207113149, Length=242, Percent_Identity=42.9752066115703, Blast_Score=187, Evalue=9e-48,
Organism=Homo sapiens, GI296011028, Length=180, Percent_Identity=44.4444444444444, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI296011030, Length=219, Percent_Identity=39.2694063926941, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI1789046, Length=195, Percent_Identity=33.8461538461538, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788021, Length=235, Percent_Identity=27.2340425531915, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787576, Length=193, Percent_Identity=28.4974093264249, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554716, Length=227, Percent_Identity=36.5638766519824, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17137324, Length=219, Percent_Identity=46.1187214611872, Blast_Score=190, Evalue=8e-49,
Organism=Drosophila melanogaster, GI116008157, Length=219, Percent_Identity=46.1187214611872, Blast_Score=186, Evalue=9e-48,
Organism=Drosophila melanogaster, GI20129151, Length=226, Percent_Identity=34.9557522123894, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45550911, Length=222, Percent_Identity=37.3873873873874, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24580849, Length=206, Percent_Identity=36.4077669902913, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45550097, Length=217, Percent_Identity=29.0322580645161, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129149, Length=221, Percent_Identity=31.6742081447964, Blast_Score=98, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25113; Mature: 24982

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQQKQRGPIKAVIFDMDGLLLDTEGVYTEVTHLIASRHGRTFDWSVKQHTIGRGARDF
CCCCHHHCCCEEEEEEECCCEEEECCCHHHHHHHHHHHCCCCEEECCHHHHHHCCCCHHH
SDYVIKALELPMSIDEFLEVREPMLEERFPRAAAMPGAEALVRHLAAHNIPIAVGTSSSV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCCEEECCCCCE
HYFEAKTTLHRAWFELFDTVVTADDPEVGAAKPAPDIFLVAARRLGVSPADCLVFEDSPF
EEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCCCHHEEEECCCCC
GVTAAKAAGMYAVAVPDSHMPVEQYEHADLLLGSLADFPLKAWGLPELA
CEEHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SEQQKQRGPIKAVIFDMDGLLLDTEGVYTEVTHLIASRHGRTFDWSVKQHTIGRGARDF
CCCHHHCCCEEEEEEECCCEEEECCCHHHHHHHHHHHCCCCEEECCHHHHHHCCCCHHH
SDYVIKALELPMSIDEFLEVREPMLEERFPRAAAMPGAEALVRHLAAHNIPIAVGTSSSV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCCEEECCCCCE
HYFEAKTTLHRAWFELFDTVVTADDPEVGAAKPAPDIFLVAARRLGVSPADCLVFEDSPF
EEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCCCHHEEEECCCCC
GVTAAKAAGMYAVAVPDSHMPVEQYEHADLLLGSLADFPLKAWGLPELA
CEEHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]