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The map label for this gene is oxyR [H]

Identifier: 66048168

GI number: 66048168

Start: 5859155

End: 5860036

Strand: Direct

Name: oxyR [H]

Synonym: Psyr_4944

Alternate gene names: 66048168

Gene position: 5859155-5860036 (Clockwise)

Preceding gene: 66048166

Following gene: 66048169

Centisome position: 96.15

GC content: 61.22

Gene sequence:

>882_bases
ATGGACATCAAGCAACTTAAATTTCTGATCGCCCTCGACGAGACGAGGCACTTCGGCCAGGCGGCTGCGCGTTGCAATAT
TACCCAGCCGACGCTGTCGATGCGCTTGCGCAATCTGGAAGAAGAGCTTGGCTTGCCACTGGTCAATCGCGGCCAGCGCT
TCGAGGGTTTCACTGCGCCAGGCGAACGCGTATTGGCCTGGGCACGCACGGTACTGGCGGCCTACGACGGTCTGCAGGCT
GAAGCGGCCGCCTGCCGCGGTCATCTGGTCGGGACGTTGCGCCTGGGCGTGGTGCCGCTGTCGAGCTTCGATCCGCTGCC
ATTGCTGCACCGGCTGCACCAGATGCACCCCAATCTGCGCTTCGAGCTGTCGTCACTCAGCTCCGAGCAAGTGCTGGAAC
AACTGGCGAGCAATCGTATCGACCTGGGCGTTTCGTACCTGGAACGGCTGGACAACGAGCGTTTCGATTCGCTGACCCTG
GACGACACACGCATGGGCCTGCTGTATGACCGTCGGCACTTTACCTTTGGTGACGATCCCTTGAGCTGGGCCGACCTGGT
CGAGTTGCCGCTGGGCACGCTGACCAGCGGCATGCATTTTCGCCAGTCGATCGATCACAACTTCCATAGCCGCGGCCTGC
AACCCAATCCGCTGATACAAACCGATGCCGTTCATCAGTTGCTGCAAGCCGTACACGGCGGTTTTTGCTGCGCAATCATG
CCGCTGGATGGCGGTCTGGAAACGCTGACCGAACATTTGCGTCTGCATCCGATTGCCGACTCCCGGACTTTGGCCCGGCT
GGGGTTGATCATGCGCCGCAGTGCGCCGCGCTCGGCACTGGCTGAAGCCTGCTTTGCACTGGTAGCGGAAATACCGCGCT
AG

Upstream 100 bases:

>100_bases
CTCGTAAATCAAGGGCTGCAGGCTTCCGACCAACGTAGCTCGACCATCGTTCAGCCTGAACGCGTAGAATCGGCTGTCTG
GATGGCTCACCGGAGTGAAT

Downstream 100 bases:

>100_bases
CGCGTTGATCGACGTCATCTATCGGGGCATCAGCACTAGCGATTAGACGATTTCCAATAACGGGCCTAGTCTTGCAGATG
TCATTCTGCCGGTATTTCAG

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDIKQLKFLIALDETRHFGQAAARCNITQPTLSMRLRNLEEELGLPLVNRGQRFEGFTAPGERVLAWARTVLAAYDGLQA
EAAACRGHLVGTLRLGVVPLSSFDPLPLLHRLHQMHPNLRFELSSLSSEQVLEQLASNRIDLGVSYLERLDNERFDSLTL
DDTRMGLLYDRRHFTFGDDPLSWADLVELPLGTLTSGMHFRQSIDHNFHSRGLQPNPLIQTDAVHQLLQAVHGGFCCAIM
PLDGGLETLTEHLRLHPIADSRTLARLGLIMRRSAPRSALAEACFALVAEIPR

Sequences:

>Translated_293_residues
MDIKQLKFLIALDETRHFGQAAARCNITQPTLSMRLRNLEEELGLPLVNRGQRFEGFTAPGERVLAWARTVLAAYDGLQA
EAAACRGHLVGTLRLGVVPLSSFDPLPLLHRLHQMHPNLRFELSSLSSEQVLEQLASNRIDLGVSYLERLDNERFDSLTL
DDTRMGLLYDRRHFTFGDDPLSWADLVELPLGTLTSGMHFRQSIDHNFHSRGLQPNPLIQTDAVHQLLQAVHGGFCCAIM
PLDGGLETLTEHLRLHPIADSRTLARLGLIMRRSAPRSALAEACFALVAEIPR
>Mature_293_residues
MDIKQLKFLIALDETRHFGQAAARCNITQPTLSMRLRNLEEELGLPLVNRGQRFEGFTAPGERVLAWARTVLAAYDGLQA
EAAACRGHLVGTLRLGVVPLSSFDPLPLLHRLHQMHPNLRFELSSLSSEQVLEQLASNRIDLGVSYLERLDNERFDSLTL
DDTRMGLLYDRRHFTFGDDPLSWADLVELPLGTLTSGMHFRQSIDHNFHSRGLQPNPLIQTDAVHQLLQAVHGGFCCAIM
PLDGGLETLTEHLRLHPIADSRTLARLGLIMRRSAPRSALAEACFALVAEIPR

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=243, Percent_Identity=31.6872427983539, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=24.2214532871972, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=23.0240549828179, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787879, Length=149, Percent_Identity=30.2013422818792, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994962, Length=290, Percent_Identity=26.8965517241379, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788887, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=224, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=29.4520547945205, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367136, Length=163, Percent_Identity=27.6073619631902, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787806, Length=280, Percent_Identity=22.8571428571429, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788296, Length=217, Percent_Identity=25.8064516129032, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32749; Mature: 32749

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKQLKFLIALDETRHFGQAAARCNITQPTLSMRLRNLEEELGLPLVNRGQRFEGFTAP
CCHHHEEEHEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GERVLAWARTVLAAYDGLQAEAAACRGHLVGTLRLGVVPLSSFDPLPLLHRLHQMHPNLR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCE
FELSSLSSEQVLEQLASNRIDLGVSYLERLDNERFDSLTLDDTRMGLLYDRRHFTFGDDP
EEHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHEECCCCCCCCCCC
LSWADLVELPLGTLTSGMHFRQSIDHNFHSRGLQPNPLIQTDAVHQLLQAVHGGFCCAIM
CCHHHHHHHCHHHHHCCHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
PLDGGLETLTEHLRLHPIADSRTLARLGLIMRRSAPRSALAEACFALVAEIPR
ECCCCHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIKQLKFLIALDETRHFGQAAARCNITQPTLSMRLRNLEEELGLPLVNRGQRFEGFTAP
CCHHHEEEHEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GERVLAWARTVLAAYDGLQAEAAACRGHLVGTLRLGVVPLSSFDPLPLLHRLHQMHPNLR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHCCCCE
FELSSLSSEQVLEQLASNRIDLGVSYLERLDNERFDSLTLDDTRMGLLYDRRHFTFGDDP
EEHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHEECCCCCCCCCCC
LSWADLVELPLGTLTSGMHFRQSIDHNFHSRGLQPNPLIQTDAVHQLLQAVHGGFCCAIM
CCHHHHHHHCHHHHHCCHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEE
PLDGGLETLTEHLRLHPIADSRTLARLGLIMRRSAPRSALAEACFALVAEIPR
ECCCCHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]