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The map label for this gene is dctD [H]

Identifier: 66048162

GI number: 66048162

Start: 5853956

End: 5855347

Strand: Direct

Name: dctD [H]

Synonym: Psyr_4938

Alternate gene names: 66048162

Gene position: 5853956-5855347 (Clockwise)

Preceding gene: 66048161

Following gene: 66048163

Centisome position: 96.07

GC content: 65.52

Gene sequence:

>1392_bases
ATGAGTTCGGACACAGCCATCGACAGCCAGATTCAGGTGGTGCTGATCGACGACGATTCGCACCTGCGTCAGGCCCTGCG
TCAGACGCTGGACCTGGCTGGCCTGAACGTTCTATCACTGCCCGAAGCGACCGGGCTGGCCGAGCGCATCGGCCGCGACT
GGCCGGGCGTAGTGGTCAGCGATATTCGCATGCAGGGCATGGATGGCCTGGAACTGCTCGACCAGCTTCACGCGCAGGAC
CCCGACCTGCCGGTGCTGCTGATCACCGGGCATGGCGATGTACCGTTGGCGGTAAAGGCCATGCGCGCCGGGGCCTACGA
CTTTCTGGAAAAGCCCTTCGCCAGCGACGCCATGCTCGACAGCGTGCGCCGTGCCCTGGCGCTGCGCCGTCTGGTGCTGG
ATAACCGCAGCCTGCGCCTGGCCCTGAGTGATCGCCAACAACTGAGCACACGCCTGATCGGTCAGTCGCCGCCGATCCTG
CGTCTGCGCGAACAAATCGGCGCATTGGCCGGGACGCGAGCCGACGTGCTGATCCTCGGCGAAACCGGCGCAGGCAAAGA
AGTGGTCGCCCGCGCGCTGCACGACCTGTCCAACCGCCGCAGCGGCCCGTTCGTGGCGATCAACGCCGGGGCGCTGGCTG
AATCGGTGGTGGAAAGCGAGCTGTTCGGTCACGAGCCAGGCGCCTTCACCGGCGCGCAGAAGCGGCGTATCGGCAAGTTC
GAATTTGCCAACGGCGGTACGCTGTTCCTCGATGAAATCGAAAGCATGAGCCTGGACGTGCAGGTCAAGCTGCTGCGCCT
GCTGCAGGAGCGCGTGGTTGAGCGAATGGGCAGCAATCAGCAGATCCCGCTGGACATCCGCATCATCGCCGCGACCAAGG
AAGACCTGCGTCACGCGGCCGATCAGGGCCGCTTCCGGGCAGACTTGTATTACCGCCTGAACGTGGCCTCGCTGCGTATC
CCGCCGTTGCGCGAACGGGGTGAAGATGCGCTGATGCTGTTCGAACATTACGCCGATGCCGCGAGCATGCGCCACGGCAT
CCCCAAGCACGAACTCAAGCCGGGCCAGCGCGCGCTGCTGTTGCGGCATAACTGGCCGGGCAACGTCCGGGAACTGCAAA
ACGCTGCCGAGCGCTTTGCGCTGGGTCTGGAACTGGAGCTGGAGCCGGAAGGCGTTGATGCAGAGCAGGCGCCACCGCCG
GGCGGCGGGCTGAGCGATCAGGTGGAAAGCTTCGAGCGCGCCTTGATCGCCGCCGAACTGGCGCGCCCGCACAGCTCGGT
GCGCAGCCTCGCGGAAGCGCTGGGTGTGCCGCGTAAGACCCTGCACGACAAACTGCGCAAGCACGGCCTGACGTTTGGCG
ACAGCAGTGGAGCCTCCGATGATACCGATTGA

Upstream 100 bases:

>100_bases
TGCTGTTCGCCAACCATCCCAGCGGCGGTGCGCTGCTGACCCTGCGCCTGCGTGCCGGGGCTTCCGGGGCCAATCTTCAA
CCGCCAGAGGACCTTTCTGC

Downstream 100 bases:

>100_bases
GCCTGGACATGACGCAGCCCGCGAGTTGGAACAGGTGCTGCACCACGACATCCCGCTGACCCGCGAGATGGGCATGCGCG
TGCTCGACTGGCACAACCAG

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSSDTAIDSQIQVVLIDDDSHLRQALRQTLDLAGLNVLSLPEATGLAERIGRDWPGVVVSDIRMQGMDGLELLDQLHAQD
PDLPVLLITGHGDVPLAVKAMRAGAYDFLEKPFASDAMLDSVRRALALRRLVLDNRSLRLALSDRQQLSTRLIGQSPPIL
RLREQIGALAGTRADVLILGETGAGKEVVARALHDLSNRRSGPFVAINAGALAESVVESELFGHEPGAFTGAQKRRIGKF
EFANGGTLFLDEIESMSLDVQVKLLRLLQERVVERMGSNQQIPLDIRIIAATKEDLRHAADQGRFRADLYYRLNVASLRI
PPLRERGEDALMLFEHYADAASMRHGIPKHELKPGQRALLLRHNWPGNVRELQNAAERFALGLELELEPEGVDAEQAPPP
GGGLSDQVESFERALIAAELARPHSSVRSLAEALGVPRKTLHDKLRKHGLTFGDSSGASDDTD

Sequences:

>Translated_463_residues
MSSDTAIDSQIQVVLIDDDSHLRQALRQTLDLAGLNVLSLPEATGLAERIGRDWPGVVVSDIRMQGMDGLELLDQLHAQD
PDLPVLLITGHGDVPLAVKAMRAGAYDFLEKPFASDAMLDSVRRALALRRLVLDNRSLRLALSDRQQLSTRLIGQSPPIL
RLREQIGALAGTRADVLILGETGAGKEVVARALHDLSNRRSGPFVAINAGALAESVVESELFGHEPGAFTGAQKRRIGKF
EFANGGTLFLDEIESMSLDVQVKLLRLLQERVVERMGSNQQIPLDIRIIAATKEDLRHAADQGRFRADLYYRLNVASLRI
PPLRERGEDALMLFEHYADAASMRHGIPKHELKPGQRALLLRHNWPGNVRELQNAAERFALGLELELEPEGVDAEQAPPP
GGGLSDQVESFERALIAAELARPHSSVRSLAEALGVPRKTLHDKLRKHGLTFGDSSGASDDTD
>Mature_462_residues
SSDTAIDSQIQVVLIDDDSHLRQALRQTLDLAGLNVLSLPEATGLAERIGRDWPGVVVSDIRMQGMDGLELLDQLHAQDP
DLPVLLITGHGDVPLAVKAMRAGAYDFLEKPFASDAMLDSVRRALALRRLVLDNRSLRLALSDRQQLSTRLIGQSPPILR
LREQIGALAGTRADVLILGETGAGKEVVARALHDLSNRRSGPFVAINAGALAESVVESELFGHEPGAFTGAQKRRIGKFE
FANGGTLFLDEIESMSLDVQVKLLRLLQERVVERMGSNQQIPLDIRIIAATKEDLRHAADQGRFRADLYYRLNVASLRIP
PLRERGEDALMLFEHYADAASMRHGIPKHELKPGQRALLLRHNWPGNVRELQNAAERFALGLELELEPEGVDAEQAPPPG
GGLSDQVESFERALIAAELARPHSSVRSLAEALGVPRKTLHDKLRKHGLTFGDSSGASDDTD

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=463, Percent_Identity=38.8768898488121, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1790299, Length=468, Percent_Identity=38.8888888888889, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1790437, Length=443, Percent_Identity=39.9548532731377, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI1788905, Length=374, Percent_Identity=43.5828877005348, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=42.4528301886792, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87082117, Length=236, Percent_Identity=49.1525423728814, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789087, Length=333, Percent_Identity=41.1411411411411, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1786524, Length=272, Percent_Identity=44.8529411764706, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=38.4615384615385, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=45.8874458874459, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1787583, Length=312, Percent_Identity=38.4615384615385, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1789828, Length=250, Percent_Identity=37.2, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87081858, Length=287, Percent_Identity=29.9651567944251, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50683; Mature: 50552

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDTAIDSQIQVVLIDDDSHLRQALRQTLDLAGLNVLSLPEATGLAERIGRDWPGVVVS
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHCCCCCCHHHH
DIRMQGMDGLELLDQLHAQDPDLPVLLITGHGDVPLAVKAMRAGAYDFLEKPFASDAMLD
HHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHCCCCCHHHHH
SVRRALALRRLVLDNRSLRLALSDRQQLSTRLIGQSPPILRLREQIGALAGTRADVLILG
HHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEE
ETGAGKEVVARALHDLSNRRSGPFVAINAGALAESVVESELFGHEPGAFTGAQKRRIGKF
CCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCE
EFANGGTLFLDEIESMSLDVQVKLLRLLQERVVERMGSNQQIPLDIRIIAATKEDLRHAA
EECCCCEEEEECHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHH
DQGRFRADLYYRLNVASLRIPPLRERGEDALMLFEHYADAASMRHGIPKHELKPGQRALL
HCCCEEEEEEEEEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEE
LRHNWPGNVRELQNAAERFALGLELELEPEGVDAEQAPPPGGGLSDQVESFERALIAAEL
EEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARPHSSVRSLAEALGVPRKTLHDKLRKHGLTFGDSSGASDDTD
HCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSDTAIDSQIQVVLIDDDSHLRQALRQTLDLAGLNVLSLPEATGLAERIGRDWPGVVVS
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHCCCCCCHHHH
DIRMQGMDGLELLDQLHAQDPDLPVLLITGHGDVPLAVKAMRAGAYDFLEKPFASDAMLD
HHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHCCCCCHHHHH
SVRRALALRRLVLDNRSLRLALSDRQQLSTRLIGQSPPILRLREQIGALAGTRADVLILG
HHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEE
ETGAGKEVVARALHDLSNRRSGPFVAINAGALAESVVESELFGHEPGAFTGAQKRRIGKF
CCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCE
EFANGGTLFLDEIESMSLDVQVKLLRLLQERVVERMGSNQQIPLDIRIIAATKEDLRHAA
EECCCCEEEEECHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHH
DQGRFRADLYYRLNVASLRIPPLRERGEDALMLFEHYADAASMRHGIPKHELKPGQRALL
HCCCEEEEEEEEEEEEEEECCCCHHCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEE
LRHNWPGNVRELQNAAERFALGLELELEPEGVDAEQAPPPGGGLSDQVESFERALIAAEL
EEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARPHSSVRSLAEALGVPRKTLHDKLRKHGLTFGDSSGASDDTD
HCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]