Click here to switch to the map view.

The map label for this gene is dctB [H]

Identifier: 66048161

GI number: 66048161

Start: 5852145

End: 5853959

Strand: Direct

Name: dctB [H]

Synonym: Psyr_4937

Alternate gene names: 66048161

Gene position: 5852145-5853959 (Clockwise)

Preceding gene: 66048160

Following gene: 66048162

Centisome position: 96.04

GC content: 64.57

Gene sequence:

>1815_bases
ATGACCATGACTCCCGCTCTGCCGCCCCGCCCTCGCTGGCGCAGCCTTGCCCTTCTGGCACTCTGCCTGGCGCCGTTGCT
GTGGCCGCTGGAGCATCTGGCCGAACGTTATTACCGCAACGTGCTGGCCAATCAGAACCGCCAGACCCTGGACCTGTACG
TCGCCAACCTGCTGGGCACCCTGCACCGTTACGAAACCCTGCCGCAGATCCTCGGCGACCTGCCGGCCTTGCGCGCCGCA
CTGGCGGCACCGGGCGACACACCTACCCTGGTAAACGCCAACCGTCTGCTCAGCGAAATCACGCGTCAGACCGGTGCCGA
TGTCATGTACCTGATGGACGCAAACGGCCTGACCCTGGCGGCCTCCAACTCGGATCACAAGGACAGTTTCATTGGCCGAA
ACTTCTCGTTCAGGCCCTATTTCATCGATGCGCGGGCGGGCAGAACCGGGCGGTTCTTCGGCCTCGGCACGACCTCTGCC
AAACGTGGCTACTTTTTCGCCGGCCCGGTGCGTGACGGTGAGCGAATCATCGGCGTGCTGGTGGTCAAGGTCGATCTGGA
CCACACCGAAACCCTGTGGGGCAAGACGCCCGAGCAACTGCTGCTGACCGACCAGAACGGCGTGGTGATTCTGACCTCCA
ACCCCGAATGGCGTTTTCGGGCGACCCGCGACCTGACCGATGACGAGAAAAAAGCCATCGTCGCGATCCAGTCCTACCCG
ACCCGCGATCCGCGCCCGTTGAGGATCGATGAAAACGCCTGGCTGACCCAGACCCAGGCCATCGAAGAGACCGGCTGGAA
CGTCAACATCCTCGCGCCTCGCGCCCTTGTCGACCGTCAGGTGCGCACGGTGGTGGCGATTGGCGGCGCAGCGCTGCTGG
TGCTGATGTTGTTGCTGGGCCTGATGATGCAGCGTCGTCGTCATTATCTGGACCGCATCGCTTTCGAGGCCAAGGCGCGC
CGCGAGCTGGAGATGCGGGTTATCGAGCGGACCAGCGATCTGGAGGGGCTCAACAGCCGTCTGCGCCAAGAAGTGCTGGA
GCGCGAGCAGGCGCAGCAGGAACTGGTGCAGGCTCAGGACGAACTGGTGCAGACCAGCAAACTGACGGCGCTGGGCACCA
TGTCGGCGAGTATCAGCCATGAGCTGAATCAGCCGTTGGCCGCTATCCGCAGTTACGCCGAAAACGCCGAAGTGCTGCTC
GATCATCAGCGCACCGAGGACGCCCGCGGCAACCTCAAGCTGATCAGCGAACTGACCGGGCGCATGGCCTCGATCATCGC
GCACTTGCGCGCCTTCGCCCGTCGCGACCGCCACGCCCCTGAAAGCGTGGCACTGCAACCGGCGCTGGAAGATGCGCTGG
CGCTGCTGGCCAAACGGCGGCGCGCCATGGAAGTCGAACTGATCCGTGACCTGCCGGACGCCACGATCTGGGTGCAGGCC
GGTGAAACCCGTCTGCGTCAGGTGCTCGGCAATCTGATCGCCAACGCGCTGGACGCCCTCACTGAAAAAGGCCCGCCGCG
CCGGCTGTGGATAAGTGTCGAGCAAACCGCCGAGGGCGTTAACCTGTACATTCGTGACAACGGCCCCGGCTTTTCCCAGG
AAGCACTGGCGCGGGCCCGCGAGCCCTTCTTCACGACCAAGACCCGCACCCAGGGCCTTGGCCTCGGTCTGGCTATCTGC
GATACGCTGATGCGCGCGCTGGGCGGCGAATTGCTGTTCGCCAACCATCCCAGCGGCGGTGCGCTGCTGACCCTGCGCCT
GCGTGCCGGGGCTTCCGGGGCCAATCTTCAACCGCCAGAGGACCTTTCTGCATGA

Upstream 100 bases:

>100_bases
ACGCGCCTGATGCCCACGTCAGGATCGACCGGGTGTTTCTGTTGCCTGCCACGGCGTGATCGCCAGCAGGCATCGTCAAC
CCTTCGGCGACGGCCAATCG

Downstream 100 bases:

>100_bases
GTTCGGACACAGCCATCGACAGCCAGATTCAGGTGGTGCTGATCGACGACGATTCGCACCTGCGTCAGGCCCTGCGTCAG
ACGCTGGACCTGGCTGGCCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MTMTPALPPRPRWRSLALLALCLAPLLWPLEHLAERYYRNVLANQNRQTLDLYVANLLGTLHRYETLPQILGDLPALRAA
LAAPGDTPTLVNANRLLSEITRQTGADVMYLMDANGLTLAASNSDHKDSFIGRNFSFRPYFIDARAGRTGRFFGLGTTSA
KRGYFFAGPVRDGERIIGVLVVKVDLDHTETLWGKTPEQLLLTDQNGVVILTSNPEWRFRATRDLTDDEKKAIVAIQSYP
TRDPRPLRIDENAWLTQTQAIEETGWNVNILAPRALVDRQVRTVVAIGGAALLVLMLLLGLMMQRRRHYLDRIAFEAKAR
RELEMRVIERTSDLEGLNSRLRQEVLEREQAQQELVQAQDELVQTSKLTALGTMSASISHELNQPLAAIRSYAENAEVLL
DHQRTEDARGNLKLISELTGRMASIIAHLRAFARRDRHAPESVALQPALEDALALLAKRRRAMEVELIRDLPDATIWVQA
GETRLRQVLGNLIANALDALTEKGPPRRLWISVEQTAEGVNLYIRDNGPGFSQEALARAREPFFTTKTRTQGLGLGLAIC
DTLMRALGGELLFANHPSGGALLTLRLRAGASGANLQPPEDLSA

Sequences:

>Translated_604_residues
MTMTPALPPRPRWRSLALLALCLAPLLWPLEHLAERYYRNVLANQNRQTLDLYVANLLGTLHRYETLPQILGDLPALRAA
LAAPGDTPTLVNANRLLSEITRQTGADVMYLMDANGLTLAASNSDHKDSFIGRNFSFRPYFIDARAGRTGRFFGLGTTSA
KRGYFFAGPVRDGERIIGVLVVKVDLDHTETLWGKTPEQLLLTDQNGVVILTSNPEWRFRATRDLTDDEKKAIVAIQSYP
TRDPRPLRIDENAWLTQTQAIEETGWNVNILAPRALVDRQVRTVVAIGGAALLVLMLLLGLMMQRRRHYLDRIAFEAKAR
RELEMRVIERTSDLEGLNSRLRQEVLEREQAQQELVQAQDELVQTSKLTALGTMSASISHELNQPLAAIRSYAENAEVLL
DHQRTEDARGNLKLISELTGRMASIIAHLRAFARRDRHAPESVALQPALEDALALLAKRRRAMEVELIRDLPDATIWVQA
GETRLRQVLGNLIANALDALTEKGPPRRLWISVEQTAEGVNLYIRDNGPGFSQEALARAREPFFTTKTRTQGLGLGLAIC
DTLMRALGGELLFANHPSGGALLTLRLRAGASGANLQPPEDLSA
>Mature_603_residues
TMTPALPPRPRWRSLALLALCLAPLLWPLEHLAERYYRNVLANQNRQTLDLYVANLLGTLHRYETLPQILGDLPALRAAL
AAPGDTPTLVNANRLLSEITRQTGADVMYLMDANGLTLAASNSDHKDSFIGRNFSFRPYFIDARAGRTGRFFGLGTTSAK
RGYFFAGPVRDGERIIGVLVVKVDLDHTETLWGKTPEQLLLTDQNGVVILTSNPEWRFRATRDLTDDEKKAIVAIQSYPT
RDPRPLRIDENAWLTQTQAIEETGWNVNILAPRALVDRQVRTVVAIGGAALLVLMLLLGLMMQRRRHYLDRIAFEAKARR
ELEMRVIERTSDLEGLNSRLRQEVLEREQAQQELVQAQDELVQTSKLTALGTMSASISHELNQPLAAIRSYAENAEVLLD
HQRTEDARGNLKLISELTGRMASIIAHLRAFARRDRHAPESVALQPALEDALALLAKRRRAMEVELIRDLPDATIWVQAG
ETRLRQVLGNLIANALDALTEKGPPRRLWISVEQTAEGVNLYIRDNGPGFSQEALARAREPFFTTKTRTQGLGLGLAICD
TLMRALGGELLFANHPSGGALLTLRLRAGASGANLQPPEDLSA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=27.8969957081545, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=29.8755186721992, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=25.1937984496124, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=279, Percent_Identity=27.2401433691756, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=220, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=31.1926605504587, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=283, Percent_Identity=26.5017667844523, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67194; Mature: 67063

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTPALPPRPRWRSLALLALCLAPLLWPLEHLAERYYRNVLANQNRQTLDLYVANLLGT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LHRYETLPQILGDLPALRAALAAPGDTPTLVNANRLLSEITRQTGADVMYLMDANGLTLA
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCEECHHHHHHHHHHHCCCCEEEEEECCCEEEE
ASNSDHKDSFIGRNFSFRPYFIDARAGRTGRFFGLGTTSAKRGYFFAGPVRDGERIIGVL
ECCCCCCHHHCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCEEEECCCCCCCEEEEEE
VVKVDLDHTETLWGKTPEQLLLTDQNGVVILTSNPEWRFRATRDLTDDEKKAIVAIQSYP
EEEEECCCCHHHCCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCCCCCEEEEEECCC
TRDPRPLRIDENAWLTQTQAIEETGWNVNILAPRALVDRQVRTVVAIGGAALLVLMLLLG
CCCCCCEEECCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHH
LMMQRRRHYLDRIAFEAKARRELEMRVIERTSDLEGLNSRLRQEVLEREQAQQELVQAQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVQTSKLTALGTMSASISHELNQPLAAIRSYAENAEVLLDHQRTEDARGNLKLISELTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
RMASIIAHLRAFARRDRHAPESVALQPALEDALALLAKRRRAMEVELIRDLPDATIWVQA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GETRLRQVLGNLIANALDALTEKGPPRRLWISVEQTAEGVNLYIRDNGPGFSQEALARAR
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHC
EPFFTTKTRTQGLGLGLAICDTLMRALGGELLFANHPSGGALLTLRLRAGASGANLQPPE
CCCEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCC
DLSA
CCCC
>Mature Secondary Structure 
TMTPALPPRPRWRSLALLALCLAPLLWPLEHLAERYYRNVLANQNRQTLDLYVANLLGT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LHRYETLPQILGDLPALRAALAAPGDTPTLVNANRLLSEITRQTGADVMYLMDANGLTLA
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCEECHHHHHHHHHHHCCCCEEEEEECCCEEEE
ASNSDHKDSFIGRNFSFRPYFIDARAGRTGRFFGLGTTSAKRGYFFAGPVRDGERIIGVL
ECCCCCCHHHCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCEEEECCCCCCCEEEEEE
VVKVDLDHTETLWGKTPEQLLLTDQNGVVILTSNPEWRFRATRDLTDDEKKAIVAIQSYP
EEEEECCCCHHHCCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCCCCCEEEEEECCC
TRDPRPLRIDENAWLTQTQAIEETGWNVNILAPRALVDRQVRTVVAIGGAALLVLMLLLG
CCCCCCEEECCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHH
LMMQRRRHYLDRIAFEAKARRELEMRVIERTSDLEGLNSRLRQEVLEREQAQQELVQAQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVQTSKLTALGTMSASISHELNQPLAAIRSYAENAEVLLDHQRTEDARGNLKLISELTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
RMASIIAHLRAFARRDRHAPESVALQPALEDALALLAKRRRAMEVELIRDLPDATIWVQA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GETRLRQVLGNLIANALDALTEKGPPRRLWISVEQTAEGVNLYIRDNGPGFSQEALARAR
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHC
EPFFTTKTRTQGLGLGLAICDTLMRALGGELLFANHPSGGALLTLRLRAGASGANLQPPE
CCCEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCC
DLSA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]