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The map label for this gene is yafC [C]

Identifier: 66048147

GI number: 66048147

Start: 5836551

End: 5837453

Strand: Direct

Name: yafC [C]

Synonym: Psyr_4923

Alternate gene names: 66048147

Gene position: 5836551-5837453 (Clockwise)

Preceding gene: 66048142

Following gene: 66048148

Centisome position: 95.78

GC content: 54.15

Gene sequence:

>903_bases
ATGAAAAGAGGCGTGATGGACCGGTTGTTACTGATGAGCTGTTTTGTACGCGCTGTCGAGACAGGTAGTTTCTCTGCTGC
GGGACGTGATCTAGGACTAGGGCAACCGAACGTCAGTCGTTACGTCGCTGCTCTTGAAGACCATTTGCAAACCAGGCTGC
TTCACCGATCCACACGAAAGCTGATGCTCACGCCCGAGGGTGAACGGTACTACGCGGATGCGCTGCGTATTCTGGACTCA
GTGGAACAGTCAGAGTCCTCACTGAGAGGGAACGTAGCGCCGTCTGGGTTACTGCGAGTCGCTTGCCCGACCGCATTGGC
TCACACCTTCATCGTACCGCACGTCGCGAGCTTTCTAGCGCGTTATCCCGAACTGTCGCTCGATCTTCAAATCAATGATC
GCTACGTCAATTTAATCGACGAGGGGGTAGAACTCGCGATTCGTATTGGGCACCTGGAGGACAGTGCAATGCGAGCCCGG
CCACTAGCATCGTTCGAACGTGTGTGCGTTGCCAGCCGTGCGTACCTAGAGAAACGTGGCTCTCCCTCTTCGCCTGATGA
CCTGAAGGAACACGACTGCCTCATTTATACCCTCCTATCCACTGGAACCAACTGGCGGTTTAAGAATACTGATGTCCCGG
TCTCCGGACGACTGCGTGTCAACTCGCCTGAGGCGATACGTGAGTACGTCAATGCAGGATTGGGAATCGCGCAGGGGCCT
CAATGGCTTTATGAGGAAGGGCTCAGAAGTGGCAATCTTCAATTGCTGCTTAACGAATACGTGGCGCCACCCGTCCCGAT
CCAATTCGTATACTTAGCGAATCGGCTGCTGCCCCAGCGAGCGATCGTTTTCATGGATTTTATGGCGGATGTTTTTGCTG
CATTCCATGATCGCCCTAAATAG

Upstream 100 bases:

>100_bases
GTTCGGCCAGCCGGACGGCTGACCTTCTGAGAGCAACTATGTATTCATGCCAACGCACTGATAAGATGGGCAAATAGAAT
AGATCTCATGCAAAATCTGC

Downstream 100 bases:

>100_bases
CCTAGACCACGGCCAAGGTGCGAACGAAGAACCATTAGCATGGGCGGTAACATGCGGTTAAGGAAACGGAAGCAGATTTA
TTTGGATAAACGACCGCTTC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKRGVMDRLLLMSCFVRAVETGSFSAAGRDLGLGQPNVSRYVAALEDHLQTRLLHRSTRKLMLTPEGERYYADALRILDS
VEQSESSLRGNVAPSGLLRVACPTALAHTFIVPHVASFLARYPELSLDLQINDRYVNLIDEGVELAIRIGHLEDSAMRAR
PLASFERVCVASRAYLEKRGSPSSPDDLKEHDCLIYTLLSTGTNWRFKNTDVPVSGRLRVNSPEAIREYVNAGLGIAQGP
QWLYEEGLRSGNLQLLLNEYVAPPVPIQFVYLANRLLPQRAIVFMDFMADVFAAFHDRPK

Sequences:

>Translated_300_residues
MKRGVMDRLLLMSCFVRAVETGSFSAAGRDLGLGQPNVSRYVAALEDHLQTRLLHRSTRKLMLTPEGERYYADALRILDS
VEQSESSLRGNVAPSGLLRVACPTALAHTFIVPHVASFLARYPELSLDLQINDRYVNLIDEGVELAIRIGHLEDSAMRAR
PLASFERVCVASRAYLEKRGSPSSPDDLKEHDCLIYTLLSTGTNWRFKNTDVPVSGRLRVNSPEAIREYVNAGLGIAQGP
QWLYEEGLRSGNLQLLLNEYVAPPVPIQFVYLANRLLPQRAIVFMDFMADVFAAFHDRPK
>Mature_300_residues
MKRGVMDRLLLMSCFVRAVETGSFSAAGRDLGLGQPNVSRYVAALEDHLQTRLLHRSTRKLMLTPEGERYYADALRILDS
VEQSESSLRGNVAPSGLLRVACPTALAHTFIVPHVASFLARYPELSLDLQINDRYVNLIDEGVELAIRIGHLEDSAMRAR
PLASFERVCVASRAYLEKRGSPSSPDDLKEHDCLIYTLLSTGTNWRFKNTDVPVSGRLRVNSPEAIREYVNAGLGIAQGP
QWLYEEGLRSGNLQLLLNEYVAPPVPIQFVYLANRLLPQRAIVFMDFMADVFAAFHDRPK

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=284, Percent_Identity=36.6197183098592, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=35.0819672131148, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=34.2281879194631, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=31.25, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=31.3380281690141, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787128, Length=281, Percent_Identity=24.5551601423488, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787589, Length=274, Percent_Identity=27.7372262773723, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790011, Length=248, Percent_Identity=27.8225806451613, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789173, Length=183, Percent_Identity=28.9617486338798, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788706, Length=265, Percent_Identity=26.7924528301887, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786448, Length=245, Percent_Identity=27.7551020408163, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33571; Mature: 33571

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGVMDRLLLMSCFVRAVETGSFSAAGRDLGLGQPNVSRYVAALEDHLQTRLLHRSTRK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCE
LMLTPEGERYYADALRILDSVEQSESSLRGNVAPSGLLRVACPTALAHTFIVPHVASFLA
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYPELSLDLQINDRYVNLIDEGVELAIRIGHLEDSAMRARPLASFERVCVASRAYLEKRG
HCCCCEEEEEECCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SPSSPDDLKEHDCLIYTLLSTGTNWRFKNTDVPVSGRLRVNSPEAIREYVNAGLGIAQGP
CCCCCCCHHHCCEEEEEEECCCCCCEEECCCCCCCCEEEECCHHHHHHHHHCCCCCCCCC
QWLYEEGLRSGNLQLLLNEYVAPPVPIQFVYLANRLLPQRAIVFMDFMADVFAAFHDRPK
HHHHHHCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRGVMDRLLLMSCFVRAVETGSFSAAGRDLGLGQPNVSRYVAALEDHLQTRLLHRSTRK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCE
LMLTPEGERYYADALRILDSVEQSESSLRGNVAPSGLLRVACPTALAHTFIVPHVASFLA
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYPELSLDLQINDRYVNLIDEGVELAIRIGHLEDSAMRARPLASFERVCVASRAYLEKRG
HCCCCEEEEEECCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SPSSPDDLKEHDCLIYTLLSTGTNWRFKNTDVPVSGRLRVNSPEAIREYVNAGLGIAQGP
CCCCCCCHHHCCEEEEEEECCCCCCEEECCCCCCCCEEEECCHHHHHHHHHCCCCCCCCC
QWLYEEGLRSGNLQLLLNEYVAPPVPIQFVYLANRLLPQRAIVFMDFMADVFAAFHDRPK
HHHHHHCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]