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The map label for this gene is occM [H]

Identifier: 66048138

GI number: 66048138

Start: 5825925

End: 5826614

Strand: Direct

Name: occM [H]

Synonym: Psyr_4914

Alternate gene names: 66048138

Gene position: 5825925-5826614 (Clockwise)

Preceding gene: 66048137

Following gene: 66048139

Centisome position: 95.61

GC content: 63.48

Gene sequence:

>690_bases
ATGAACTGGGAAGTCATCATCAAGTGGCTGCCACGCCTGGCACAGGGCGCAACCCTGACGCTGGAACTGGTGGCGATTGC
CGTCATCGCCGGGCTGATCCTTGCCATCCCGATGGGCATCGCCCGCGCATCGCGCCACTGGCCGGTGCGCGCCCTGCCCT
ACGCCTACATCTTTTTCTTCCGCGGCACACCACTGCTGGTGCAACTGTTCCTGGTCTATTACGGGCTGGCGCAGTTCGAG
TCGGTGCGCCAGAGTGCGCTGTGGCCGTACCTGCGCGACCCGTTCTGGTGTGCCGTGGTGACCATGACCCTGCACACCGC
CGCCTACATCGCCGAGATCCTGCGTGGCGCCATGCAGGCTGTGCCGCCAGGTGAAGTCGAAGCGGCACGGGCGCTGGGCA
TGTCGAAATGGAAGGCGCTGTTCTATATCGTCCTGCCACGCGCGGCACGCATCGGCCTGCCGGCCTACAGCAATGAAGTG
ATCCTGATGCTCAAGGCCAGTGCGCTGGCCAGCACCGTCACCCTGCTGGAACTGACCGGCATGGCGCGCACGATCATCGC
CCGCACCTACCTGCCAGTGGAAATCTTCTTCGCCGCCGGCATGTTCTACCTGGTCATGACCTTCGTGCTGGTACAGGGCT
TCCGGCTGCTGGAAAAACTATTGCGTGTAGACGCAAGCCAAGGGCGCTGA

Upstream 100 bases:

>100_bases
TGGTCGCGGCCTTCATGTACCTGGGCCTGACCGTGCTGGCCATGGCCGGCATGTACTTCCTTGAAAAACGCGCCAGTCGC
GGCTTTCTGAGGAGCGCGTC

Downstream 100 bases:

>100_bases
TATGAAAGGCGCTGGCGTCGATCCAGTCAGCACCTTGCCATACGAGTCCGCCACCATGCCCTCTGAACCTCGCTTGCAGG
ATGAACACCTCGGCAGCCAC

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNWEVIIKWLPRLAQGATLTLELVAIAVIAGLILAIPMGIARASRHWPVRALPYAYIFFFRGTPLLVQLFLVYYGLAQFE
SVRQSALWPYLRDPFWCAVVTMTLHTAAYIAEILRGAMQAVPPGEVEAARALGMSKWKALFYIVLPRAARIGLPAYSNEV
ILMLKASALASTVTLLELTGMARTIIARTYLPVEIFFAAGMFYLVMTFVLVQGFRLLEKLLRVDASQGR

Sequences:

>Translated_229_residues
MNWEVIIKWLPRLAQGATLTLELVAIAVIAGLILAIPMGIARASRHWPVRALPYAYIFFFRGTPLLVQLFLVYYGLAQFE
SVRQSALWPYLRDPFWCAVVTMTLHTAAYIAEILRGAMQAVPPGEVEAARALGMSKWKALFYIVLPRAARIGLPAYSNEV
ILMLKASALASTVTLLELTGMARTIIARTYLPVEIFFAAGMFYLVMTFVLVQGFRLLEKLLRVDASQGR
>Mature_229_residues
MNWEVIIKWLPRLAQGATLTLELVAIAVIAGLILAIPMGIARASRHWPVRALPYAYIFFFRGTPLLVQLFLVYYGLAQFE
SVRQSALWPYLRDPFWCAVVTMTLHTAAYIAEILRGAMQAVPPGEVEAARALGMSKWKALFYIVLPRAARIGLPAYSNEV
ILMLKASALASTVTLLELTGMARTIIARTYLPVEIFFAAGMFYLVMTFVLVQGFRLLEKLLRVDASQGR

Specific function: Component of the octopine active transport system probably consisting of four subunits:Q, M, P and T [H]

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788645, Length=205, Percent_Identity=43.9024390243902, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1787086, Length=219, Percent_Identity=40.6392694063927, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=39.6135265700483, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787030, Length=223, Percent_Identity=34.9775784753363, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787087, Length=212, Percent_Identity=30.6603773584906, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786873, Length=207, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=29.4685990338164, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788646, Length=197, Percent_Identity=29.9492385786802, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1786874, Length=218, Percent_Identity=27.0642201834862, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI48994930, Length=110, Percent_Identity=30, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25582; Mature: 25582

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWEVIIKWLPRLAQGATLTLELVAIAVIAGLILAIPMGIARASRHWPVRALPYAYIFFF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RGTPLLVQLFLVYYGLAQFESVRQSALWPYLRDPFWCAVVTMTLHTAAYIAEILRGAMQA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VPPGEVEAARALGMSKWKALFYIVLPRAARIGLPAYSNEVILMLKASALASTVTLLELTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
MARTIIARTYLPVEIFFAAGMFYLVMTFVLVQGFRLLEKLLRVDASQGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNWEVIIKWLPRLAQGATLTLELVAIAVIAGLILAIPMGIARASRHWPVRALPYAYIFFF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RGTPLLVQLFLVYYGLAQFESVRQSALWPYLRDPFWCAVVTMTLHTAAYIAEILRGAMQA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VPPGEVEAARALGMSKWKALFYIVLPRAARIGLPAYSNEVILMLKASALASTVTLLELTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
MARTIIARTYLPVEIFFAAGMFYLVMTFVLVQGFRLLEKLLRVDASQGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1655707; 1732218 [H]