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The map label for this gene is glnA [H]

Identifier: 66048041

GI number: 66048041

Start: 5714118

End: 5715524

Strand: Direct

Name: glnA [H]

Synonym: Psyr_4817

Alternate gene names: 66048041

Gene position: 5714118-5715524 (Clockwise)

Preceding gene: 66048038

Following gene: 66048042

Centisome position: 93.77

GC content: 57.85

Gene sequence:

>1407_bases
ATGTCGAAGTCGGTTCAACTCATCAAAGATCATGACGTTAAGTGGATTGATCTGCGCTTCACGGACACCAAGGGCAAGCA
GCAGCACGTCACCATGCCTGCGCGCGATGCACTGGAAGACGATTTCTTCGAAGTCGGCAAAATGTTCGACGGTTCCTCCA
TCGCTGGCTGGAAAGGCATCGAAGCGTCCGACATGATTCTTCTGCCAGATGACGAAACCGCCCTGCTCGACCCGTTCACC
GAAGAGCCGACCCTGGTTCTGGTCTGCGACGTCATCGAACCTTCGACCATGCAAGGCTACGACCGCGACCCGCGCGCCAT
TGCCCACCGTGCCGAGGAATACCTGAAGTCGACCGGTATCGGCGACACCGTATTCGTAGGTCCGGAGCCAGAGTTCTTCA
TCTTCGACGAAGTGAAATTCAAGTCCGACATCTCCGGTTCCATGTTCAAGATCTTCTCCGAACAGGCTTCCTGGATGACC
GACGGCGACGTCGATGGCGGCAACAAGGGCCACCGTCCGGGCGTCAAAGGTGGTTACTTCCCGCTGCCACCGGTCGATCA
CGACCACGAAATCCGCACCGCCATGTGCAACGCTCTGGAAGAAATGGGCCAGACCGTTGAAGTTCACCACCACGAAGTGG
CGACTGCCGGCCAGAACGAAATCGGCGTGAAATTCAACACGCTGGTCAAGAAGGCTGACGAAGTTCAGACCCTCAAGTAC
TGCGTACACAACGTTGCCGACGCTTACGGCCGTACCGCTACTTTCATGCCCAAGCCACTGTACGGTGACAACGGCTCGGG
TATGCACGTACACATGTCCATCTCCAAGGATGGCAAGAACACCTTCGCAGGCGAAGGCTACGCCGGTCTGTCCGATACCG
CCCTGTACTTCATCGGCGGCATCATCAAGCACGGCAAGGCGCTGAACGGCTTCACCAACCCGTCGACCAACTCCTACAAG
CGTCTGGTCCCGGGTTTCGAAGCACCGGTCATGCTGGCCTACTCGGCGCGTAACCGCTCCGCATCGATCCGTATTCCTTA
CGTCAACAGCCCACGCGGCCGCCGTATCGAAGCACGCTTCCCGGATCCGGCAGCCAACCCGTACCTGGCCTTCGCGGCCC
TGTTGATGGCTGGCCTGGACGGCATCCAGAACAAGATCCACCCTGGCGACGCAGCTGACAAAAACCTGTATGACCTGCCG
CCTGAAGAGGCCAAAGAGATCCCACAAGTTTGCGGCAGCCTGAAAGAAGCCCTGGAAGAACTGGACAAGGGCCGCGCGTT
CCTGACCAAGGGCGGCGTCTTCAGCGACGACTTCATCGATGCCTACATCGAGCTGAAAAGCGAAGAAGAAATCAAGGTTC
GCACCTTCGTACACCCACTGGAATACGAGCTGTACTACAGCTGCTGA

Upstream 100 bases:

>100_bases
TGTGAGGCAGGTTGCCTTGGCAGAGTATCTGCGCCGGCATCACCCAAATTCAAGGGACCATAACTCTATCAAGTCGGTCT
CTAGCCACCCGGAGGACACC

Downstream 100 bases:

>100_bases
TCCAGCCACGCCAGCGTTGATGGCGTAACAGGAGACCTCCTTCGGGAGGTCTTTTTTTGCCCGGATTTTACCGCGTGAAC
ATTTGTTCACCCCGCAACAC

Product: glutamine synthetase type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSKSVQLIKDHDVKWIDLRFTDTKGKQQHVTMPARDALEDDFFEVGKMFDGSSIAGWKGIEASDMILLPDDETALLDPFT
EEPTLVLVCDVIEPSTMQGYDRDPRAIAHRAEEYLKSTGIGDTVFVGPEPEFFIFDEVKFKSDISGSMFKIFSEQASWMT
DGDVDGGNKGHRPGVKGGYFPLPPVDHDHEIRTAMCNALEEMGQTVEVHHHEVATAGQNEIGVKFNTLVKKADEVQTLKY
CVHNVADAYGRTATFMPKPLYGDNGSGMHVHMSISKDGKNTFAGEGYAGLSDTALYFIGGIIKHGKALNGFTNPSTNSYK
RLVPGFEAPVMLAYSARNRSASIRIPYVNSPRGRRIEARFPDPAANPYLAFAALLMAGLDGIQNKIHPGDAADKNLYDLP
PEEAKEIPQVCGSLKEALEELDKGRAFLTKGGVFSDDFIDAYIELKSEEEIKVRTFVHPLEYELYYSC

Sequences:

>Translated_468_residues
MSKSVQLIKDHDVKWIDLRFTDTKGKQQHVTMPARDALEDDFFEVGKMFDGSSIAGWKGIEASDMILLPDDETALLDPFT
EEPTLVLVCDVIEPSTMQGYDRDPRAIAHRAEEYLKSTGIGDTVFVGPEPEFFIFDEVKFKSDISGSMFKIFSEQASWMT
DGDVDGGNKGHRPGVKGGYFPLPPVDHDHEIRTAMCNALEEMGQTVEVHHHEVATAGQNEIGVKFNTLVKKADEVQTLKY
CVHNVADAYGRTATFMPKPLYGDNGSGMHVHMSISKDGKNTFAGEGYAGLSDTALYFIGGIIKHGKALNGFTNPSTNSYK
RLVPGFEAPVMLAYSARNRSASIRIPYVNSPRGRRIEARFPDPAANPYLAFAALLMAGLDGIQNKIHPGDAADKNLYDLP
PEEAKEIPQVCGSLKEALEELDKGRAFLTKGGVFSDDFIDAYIELKSEEEIKVRTFVHPLEYELYYSC
>Mature_467_residues
SKSVQLIKDHDVKWIDLRFTDTKGKQQHVTMPARDALEDDFFEVGKMFDGSSIAGWKGIEASDMILLPDDETALLDPFTE
EPTLVLVCDVIEPSTMQGYDRDPRAIAHRAEEYLKSTGIGDTVFVGPEPEFFIFDEVKFKSDISGSMFKIFSEQASWMTD
GDVDGGNKGHRPGVKGGYFPLPPVDHDHEIRTAMCNALEEMGQTVEVHHHEVATAGQNEIGVKFNTLVKKADEVQTLKYC
VHNVADAYGRTATFMPKPLYGDNGSGMHVHMSISKDGKNTFAGEGYAGLSDTALYFIGGIIKHGKALNGFTNPSTNSYKR
LVPGFEAPVMLAYSARNRSASIRIPYVNSPRGRRIEARFPDPAANPYLAFAALLMAGLDGIQNKIHPGDAADKNLYDLPP
EEAKEIPQVCGSLKEALEELDKGRAFLTKGGVFSDDFIDAYIELKSEEEIKVRTFVHPLEYELYYSC

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=399, Percent_Identity=24.812030075188, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1790301, Length=464, Percent_Identity=67.8879310344828, Blast_Score=686, Evalue=0.0,
Organism=Escherichia coli, GI87081870, Length=178, Percent_Identity=32.0224719101124, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 51798; Mature: 51667

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSVQLIKDHDVKWIDLRFTDTKGKQQHVTMPARDALEDDFFEVGKMFDGSSIAGWKGI
CCCCCCCCCCCCEEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
EASDMILLPDDETALLDPFTEEPTLVLVCDVIEPSTMQGYDRDPRAIAHRAEEYLKSTGI
CCCCEEEECCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GDTVFVGPEPEFFIFDEVKFKSDISGSMFKIFSEQASWMTDGDVDGGNKGHRPGVKGGYF
CCEEEECCCCCEEEEECEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PLPPVDHDHEIRTAMCNALEEMGQTVEVHHHEVATAGQNEIGVKFNTLVKKADEVQTLKY
CCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHH
CVHNVADAYGRTATFMPKPLYGDNGSGMHVHMSISKDGKNTFAGEGYAGLSDTALYFIGG
HHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
IIKHGKALNGFTNPSTNSYKRLVPGFEAPVMLAYSARNRSASIRIPYVNSPRGRRIEARF
HHHCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECC
PDPAANPYLAFAALLMAGLDGIQNKIHPGDAADKNLYDLPPEEAKEIPQVCGSLKEALEE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LDKGRAFLTKGGVFSDDFIDAYIELKSEEEIKVRTFVHPLEYELYYSC
HHCCCEEEECCCCCCHHHHHHHEEECCCCCEEEEEEECCEEEEEEECC
>Mature Secondary Structure 
SKSVQLIKDHDVKWIDLRFTDTKGKQQHVTMPARDALEDDFFEVGKMFDGSSIAGWKGI
CCCCCCCCCCCEEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
EASDMILLPDDETALLDPFTEEPTLVLVCDVIEPSTMQGYDRDPRAIAHRAEEYLKSTGI
CCCCEEEECCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GDTVFVGPEPEFFIFDEVKFKSDISGSMFKIFSEQASWMTDGDVDGGNKGHRPGVKGGYF
CCEEEECCCCCEEEEECEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PLPPVDHDHEIRTAMCNALEEMGQTVEVHHHEVATAGQNEIGVKFNTLVKKADEVQTLKY
CCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHH
CVHNVADAYGRTATFMPKPLYGDNGSGMHVHMSISKDGKNTFAGEGYAGLSDTALYFIGG
HHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
IIKHGKALNGFTNPSTNSYKRLVPGFEAPVMLAYSARNRSASIRIPYVNSPRGRRIEARF
HHHCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECC
PDPAANPYLAFAALLMAGLDGIQNKIHPGDAADKNLYDLPPEEAKEIPQVCGSLKEALEE
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LDKGRAFLTKGGVFSDDFIDAYIELKSEEEIKVRTFVHPLEYELYYSC
HHCCCEEEECCCCCCHHHHHHHEEECCCCCEEEEEEECCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]