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The map label for this gene is hlyB [H]

Identifier: 66047930

GI number: 66047930

Start: 5575630

End: 5577255

Strand: Direct

Name: hlyB [H]

Synonym: Psyr_4706

Alternate gene names: 66047930

Gene position: 5575630-5577255 (Clockwise)

Preceding gene: 66047927

Following gene: 66047933

Centisome position: 91.5

GC content: 60.09

Gene sequence:

>1626_bases
ATGTCCCTGCGAAATATGAACATCGCGCCTCGAGCGTTTCTTGGATTTGCCATGATCGGCACCCTCATGCTGATTCTGGG
CGTCTTTGCACTGTCACAGATGAGCAAGATCCGCAGCGCCACCGAGGTGCTGGCCGACAGCAACGTGCCCAGCATCAAGA
GCCTCGATCGCTTCGCTGAAGTCAGCATTCGTCTGCGGGTGCTGTCCTATCGATTGCTGGTCAATCGCGATCCGGAAACC
CAGCAGAAAACCATCGAGCTGATGGCGATGCGCAACAAGCAGATCACTGACGCTCAGGCCGTTTACGAGAAGCTGATCAG
TACCCCCGACGAGCGCAACCTCTATAGCCAGTACGTGCAGTTGCTGGGCCAGTATCGCCAGCTTGAAGACCGCCTGAAAA
CGCTGACCCGTGCGAACAACATCGACGAATTGCAGGGCTTGCTCAACAACGAAATGGTCAGCAACTCCGACCAGATGAAC
GTTGTGCTGCGCAAGCTGGTGGATATCAATACGGCGCAGTTGAATGAGGTCAAGGAGCAGGCCTCCATCGAGTATGACTC
GGCATTCAATATGGTGATCGGACTGCTGATCGCCGCCACCCTGCTGACCCTCGTGTTTGCCTGGATGCTGATCAAGAGCA
TTACCACACCGATTGCCACCGCACTGCTCGCAGCGGAGACCATCGCGCAAGGCAACCTGACCCGGCCGATCAGTATCGAC
GGCACCGATGAAGCCGGTCGTCTGCTGCTGGCCATGAAAACCATGCAGGACAAGCTGCGCGATACCTTGCAGGGTATTTC
CGGCTCGGCCACGCAACTGGCTTCGGCAGCCGAAGAACTGAATGCCGTCACTGACGAAAGCGCACGCGGGCTGGTGCAGC
AGAACGACGAAATAGAACAGGCTGCCACTGCGGTCAACCAGATGACCAGCGCCGTGGAAGAAGTGGCGCGCAACGCCACC
AGCACCTCGCAGGCATCGCGCAGCGCAGCGACCTCTGCGGGCGATGGCCGCGACCTGGTTCAGGAAACCGTCAGCGCCAT
TGAGCGCATGAGTGGCGACGTGCAAGGCACCGCCGAGCTGATCATCAGCCTGGCCAATGAGTCGCGTGATATCGGCAAGG
TGCTCGACGTGATTCGCGGCCTGGCCGACCAGACCAATCTGCTGGCATTGAACGCCGCCATCGAAGCAGCGCGGGCCGGT
GAAGCAGGACGTGGCTTTGCCGTCGTCGCCGACGAAGTCCGTGCCCTGGCACATCGCACCCAGCAATCGACCAGCGAAAT
CGAACGCATGATCAGCAGCATTCAGACCGGCACGGAACAGGCCGTCAGCTCGATGCGCAACAGCACCGAACGCGCCGAAT
CGACGCTGAACATCGCCAAGGGCGCAGGCCAGGCCCTGAATACCATCAACAGCGCCGTGGAAGAGATCAACGAACGCAAC
ATGGTCATCGCCAGCGCCGCCGAAGAACAGGCACAAGTCGCCCGCGAAGTGGACCGCAACCTGGTCAACATCCGCGACCT
GTCGGCACAATCCACCAACGGCGCCAACCAGACCAGCGCAGCCAGCACCGAGCTGTCACGCCTGGCAATCGACCTCAACG
GCATGGTGGCGCGCTTCGCGCTTTGA

Upstream 100 bases:

>100_bases
GGCTCAAGACTTTAGTTGCACGTCCGATAGGCACCCCACTTACGGCTTTATCTCCGTCTCTAAATCGCATGGAACGCGTA
AATGACCCTGGAAGCTTTCT

Downstream 100 bases:

>100_bases
TGCTCGAAAACGGGCGTTTTATTTCCGGAAGCTATGTTGTGTGAAAGCCAGTCTTCGCGAACAAGTTCGCTCCTACGCCC
TTCGGGCAGAAGCAAACCGT

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSLRNMNIAPRAFLGFAMIGTLMLILGVFALSQMSKIRSATEVLADSNVPSIKSLDRFAEVSIRLRVLSYRLLVNRDPET
QQKTIELMAMRNKQITDAQAVYEKLISTPDERNLYSQYVQLLGQYRQLEDRLKTLTRANNIDELQGLLNNEMVSNSDQMN
VVLRKLVDINTAQLNEVKEQASIEYDSAFNMVIGLLIAATLLTLVFAWMLIKSITTPIATALLAAETIAQGNLTRPISID
GTDEAGRLLLAMKTMQDKLRDTLQGISGSATQLASAAEELNAVTDESARGLVQQNDEIEQAATAVNQMTSAVEEVARNAT
STSQASRSAATSAGDGRDLVQETVSAIERMSGDVQGTAELIISLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAG
EAGRGFAVVADEVRALAHRTQQSTSEIERMISSIQTGTEQAVSSMRNSTERAESTLNIAKGAGQALNTINSAVEEINERN
MVIASAAEEQAQVAREVDRNLVNIRDLSAQSTNGANQTSAASTELSRLAIDLNGMVARFAL

Sequences:

>Translated_541_residues
MSLRNMNIAPRAFLGFAMIGTLMLILGVFALSQMSKIRSATEVLADSNVPSIKSLDRFAEVSIRLRVLSYRLLVNRDPET
QQKTIELMAMRNKQITDAQAVYEKLISTPDERNLYSQYVQLLGQYRQLEDRLKTLTRANNIDELQGLLNNEMVSNSDQMN
VVLRKLVDINTAQLNEVKEQASIEYDSAFNMVIGLLIAATLLTLVFAWMLIKSITTPIATALLAAETIAQGNLTRPISID
GTDEAGRLLLAMKTMQDKLRDTLQGISGSATQLASAAEELNAVTDESARGLVQQNDEIEQAATAVNQMTSAVEEVARNAT
STSQASRSAATSAGDGRDLVQETVSAIERMSGDVQGTAELIISLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAG
EAGRGFAVVADEVRALAHRTQQSTSEIERMISSIQTGTEQAVSSMRNSTERAESTLNIAKGAGQALNTINSAVEEINERN
MVIASAAEEQAQVAREVDRNLVNIRDLSAQSTNGANQTSAASTELSRLAIDLNGMVARFAL
>Mature_540_residues
SLRNMNIAPRAFLGFAMIGTLMLILGVFALSQMSKIRSATEVLADSNVPSIKSLDRFAEVSIRLRVLSYRLLVNRDPETQ
QKTIELMAMRNKQITDAQAVYEKLISTPDERNLYSQYVQLLGQYRQLEDRLKTLTRANNIDELQGLLNNEMVSNSDQMNV
VLRKLVDINTAQLNEVKEQASIEYDSAFNMVIGLLIAATLLTLVFAWMLIKSITTPIATALLAAETIAQGNLTRPISIDG
TDEAGRLLLAMKTMQDKLRDTLQGISGSATQLASAAEELNAVTDESARGLVQQNDEIEQAATAVNQMTSAVEEVARNATS
TSQASRSAATSAGDGRDLVQETVSAIERMSGDVQGTAELIISLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAGE
AGRGFAVVADEVRALAHRTQQSTSEIERMISSIQTGTEQAVSSMRNSTERAESTLNIAKGAGQALNTINSAVEEINERNM
VIASAAEEQAQVAREVDRNLVNIRDLSAQSTNGANQTSAASTELSRLAIDLNGMVARFAL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=373, Percent_Identity=31.9034852546917, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI2367378, Length=310, Percent_Identity=32.9032258064516, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787690, Length=384, Percent_Identity=30.7291666666667, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=35.2159468438538, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1789453, Length=346, Percent_Identity=28.0346820809249, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58479; Mature: 58348

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRNMNIAPRAFLGFAMIGTLMLILGVFALSQMSKIRSATEVLADSNVPSIKSLDRFAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VSIRLRVLSYRLLVNRDPETQQKTIELMAMRNKQITDAQAVYEKLISTPDERNLYSQYVQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
LLGQYRQLEDRLKTLTRANNIDELQGLLNNEMVSNSDQMNVVLRKLVDINTAQLNEVKEQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
ASIEYDSAFNMVIGLLIAATLLTLVFAWMLIKSITTPIATALLAAETIAQGNLTRPISID
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECC
GTDEAGRLLLAMKTMQDKLRDTLQGISGSATQLASAAEELNAVTDESARGLVQQNDEIEQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHH
AATAVNQMTSAVEEVARNATSTSQASRSAATSAGDGRDLVQETVSAIERMSGDVQGTAEL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
IISLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAGEAGRGFAVVADEVRALAHRT
HHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
QQSTSEIERMISSIQTGTEQAVSSMRNSTERAESTLNIAKGAGQALNTINSAVEEINERN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MVIASAAEEQAQVAREVDRNLVNIRDLSAQSTNGANQTSAASTELSRLAIDLNGMVARFA
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
SLRNMNIAPRAFLGFAMIGTLMLILGVFALSQMSKIRSATEVLADSNVPSIKSLDRFAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VSIRLRVLSYRLLVNRDPETQQKTIELMAMRNKQITDAQAVYEKLISTPDERNLYSQYVQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
LLGQYRQLEDRLKTLTRANNIDELQGLLNNEMVSNSDQMNVVLRKLVDINTAQLNEVKEQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHH
ASIEYDSAFNMVIGLLIAATLLTLVFAWMLIKSITTPIATALLAAETIAQGNLTRPISID
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECC
GTDEAGRLLLAMKTMQDKLRDTLQGISGSATQLASAAEELNAVTDESARGLVQQNDEIEQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHH
AATAVNQMTSAVEEVARNATSTSQASRSAATSAGDGRDLVQETVSAIERMSGDVQGTAEL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
IISLANESRDIGKVLDVIRGLADQTNLLALNAAIEAARAGEAGRGFAVVADEVRALAHRT
HHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
QQSTSEIERMISSIQTGTEQAVSSMRNSTERAESTLNIAKGAGQALNTINSAVEEINERN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MVIASAAEEQAQVAREVDRNLVNIRDLSAQSTNGANQTSAASTELSRLAIDLNGMVARFA
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]