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The map label for this gene is estA [H]

Identifier: 66047833

GI number: 66047833

Start: 5462253

End: 5464175

Strand: Direct

Name: estA [H]

Synonym: Psyr_4606

Alternate gene names: 66047833

Gene position: 5462253-5464175 (Clockwise)

Preceding gene: 66047832

Following gene: 66047834

Centisome position: 89.64

GC content: 61.78

Gene sequence:

>1923_bases
ATGACCAAGACATCGAGGCGCTGGCCCTTCGCGGCCTGCCTGTTATCGCTTGCCTGCGGCACCGCTGCTGCCGCGCCCTA
TTCGACCATGGTGGTGTTCGGCGACAGCCTGGCCGATGCCGGGCAGTTTCCCGACACCGCCGGGCCCAGGGGCTCTACGC
TTCGGTTCACCAATCGGGTCGGCCCCACTTATCAGGACGGCAGTGGAGAGGTGTTCAATCTGAACTCGTCGACGCTGATC
GGCAGGATGCTCGGTGTGCCGGCAGGAGATCTGGCGGCTTCCACGTCGCCGGTCAATGCTGCGCTGGGCGCACCCGATGG
CAATAACTGGGCAGTCGGCGGCTATCGGACCGACCAGATTCTTGACTCGATCAACTCGCAATCCACCGTCGTCGACCCGA
ACACCGGCACATTGCTGCGCAGCCGGACCGGTTATCTGCCCGCCAACGGTTTTCGCGCCGACCCCAACGCGCTTTATTAC
CTGACCGGAGGCGGCAACGACTTCCTGCAGGGTCGTGTGTTGAGTGCCAGCAGCGCCGCGCAAGCTGCCAATCAGCTGGC
TGACAGCGCGCAAGCCCTGCAACAGGCCGGTGCGCGCTACATCATGGTCTGGTTGCTGCCGGATATCGGTAAAACGCCAG
CCTTGAGCGGTTCGCCACTGGCTTCGGCAACTTCCGCACTCAGCGCGGGCTTCAATCAGCAGTTAGTCAGCCGACTGGCG
CAGATCAATGCCCAGATCATTCCGCTGAATGTTCCATTGCTGATCAATGAAGTCCTCGCCGAACCGGCACGCTTCGGGTT
CGATCCCAACGAGAATCTGGTCAGTACCTGTTTCAGCGGCAATAGCTGCCGGGAAAGCACCACCAACGGCCGGTCCAGTG
CGACGCCGAATCCGAACCGGCTGTTCTTCAACGATCGCGTGCATCCGACCGAGGCCGGGCAGAGGTTGCTGGCCGACTAC
GCCTACTCGCTGCTTTCGGCCCCCTGGGAAATCTCCCTGCTGCCGGAAATGGCCAATGGCACGCTGCGCATGCATCAGGA
CGAGATCCGCGCCCAGTGGCTCAGCGACTGGGGCAACTGGCAAGGCATAGGACAGTGGCAGAGCATGCTTTCGGCAGGCG
GTCAGAAAATGGACTTCGACGCGCAGGACAGTTCGGCTGATGCTGACGGAAGAGGCTATAACCTGACCATCGGCGGCAGC
TACCGATTTGCCGAAAACTGGCGCACTGGGGTTGTCGCCGGGGCGTATCGCCAGAGTCTCGAGGCAGGGCCAAGGGATTC
GGACTACAAACTCAACAGCTACATCGCCACTGCGTTCCTGCAGTATCAGGCCAACCACTGGTGGGGTGATCTGGCGGTGT
CGGGCGGCAAACTGGACTACGAAAATGCCGAGCGCAAGTTCGCGCTGGGCGTCAGCGAAGGTCAGGAAAAAGGCGATACC
GACGGCGAAATGTGGGCTGTCAGCGGGCGGGTCGGTTTCGACATCGCGGGCCCGACCAGTCGCTGGCATCTGTCGCCTTT
CGTCAGCGCCGATTACGCGCACATCAATGTCGACGGCTACTCGGAAAAAGGCGACCGCTCGACCGCGCTGACCTTCAGTG
ACCAGACGCGCAAATCGCGGCGTGCAGGCGTGGGTGTGCAGGGCAAATTCCAGGTGACACCGAGCACACAGGTATGGGGC
GAAGTGGCCCATGAAAGGGAGTTCGAGACCGATCAGCAGGACGTGACCATGGCGCTCAACAGCGTTCAGTCGGTCGGTTT
CACGCTGCAAGGCTACACACCGCAACGCGACCTGAACCGGGCCACGCTGGGCGTCAGCCAGAAGCTGACTCAGGACCTGA
CACTGCGCGGCAATTACAACTGGCGCAAGAACGACGACGTGACCCAGCAAGGGGTGAATGTCGCGTTGAGTCTGAGTTTC
TAG

Upstream 100 bases:

>100_bases
AAAAAGCACCGCCGCAGCGCGATAATGTTCATCGAACTTTGCAGTCATGAAAAATCTTGCTACGTTTCCGGTACAAAACA
AAAACAATCGGGATCCGTTC

Downstream 100 bases:

>100_bases
ACTGCCCGCAGGAGGGAGCGTGAGGAACGATAATCTGACTATCGTGCCCATGCTCCGCGTGGGCATGCCGTTCTGGACGC
TTCGCGTCCTGTCCTGAGAA

Product: Outer membrane autotransporter barrel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MTKTSRRWPFAACLLSLACGTAAAAPYSTMVVFGDSLADAGQFPDTAGPRGSTLRFTNRVGPTYQDGSGEVFNLNSSTLI
GRMLGVPAGDLAASTSPVNAALGAPDGNNWAVGGYRTDQILDSINSQSTVVDPNTGTLLRSRTGYLPANGFRADPNALYY
LTGGGNDFLQGRVLSASSAAQAANQLADSAQALQQAGARYIMVWLLPDIGKTPALSGSPLASATSALSAGFNQQLVSRLA
QINAQIIPLNVPLLINEVLAEPARFGFDPNENLVSTCFSGNSCRESTTNGRSSATPNPNRLFFNDRVHPTEAGQRLLADY
AYSLLSAPWEISLLPEMANGTLRMHQDEIRAQWLSDWGNWQGIGQWQSMLSAGGQKMDFDAQDSSADADGRGYNLTIGGS
YRFAENWRTGVVAGAYRQSLEAGPRDSDYKLNSYIATAFLQYQANHWWGDLAVSGGKLDYENAERKFALGVSEGQEKGDT
DGEMWAVSGRVGFDIAGPTSRWHLSPFVSADYAHINVDGYSEKGDRSTALTFSDQTRKSRRAGVGVQGKFQVTPSTQVWG
EVAHEREFETDQQDVTMALNSVQSVGFTLQGYTPQRDLNRATLGVSQKLTQDLTLRGNYNWRKNDDVTQQGVNVALSLSF

Sequences:

>Translated_640_residues
MTKTSRRWPFAACLLSLACGTAAAAPYSTMVVFGDSLADAGQFPDTAGPRGSTLRFTNRVGPTYQDGSGEVFNLNSSTLI
GRMLGVPAGDLAASTSPVNAALGAPDGNNWAVGGYRTDQILDSINSQSTVVDPNTGTLLRSRTGYLPANGFRADPNALYY
LTGGGNDFLQGRVLSASSAAQAANQLADSAQALQQAGARYIMVWLLPDIGKTPALSGSPLASATSALSAGFNQQLVSRLA
QINAQIIPLNVPLLINEVLAEPARFGFDPNENLVSTCFSGNSCRESTTNGRSSATPNPNRLFFNDRVHPTEAGQRLLADY
AYSLLSAPWEISLLPEMANGTLRMHQDEIRAQWLSDWGNWQGIGQWQSMLSAGGQKMDFDAQDSSADADGRGYNLTIGGS
YRFAENWRTGVVAGAYRQSLEAGPRDSDYKLNSYIATAFLQYQANHWWGDLAVSGGKLDYENAERKFALGVSEGQEKGDT
DGEMWAVSGRVGFDIAGPTSRWHLSPFVSADYAHINVDGYSEKGDRSTALTFSDQTRKSRRAGVGVQGKFQVTPSTQVWG
EVAHEREFETDQQDVTMALNSVQSVGFTLQGYTPQRDLNRATLGVSQKLTQDLTLRGNYNWRKNDDVTQQGVNVALSLSF
>Mature_639_residues
TKTSRRWPFAACLLSLACGTAAAAPYSTMVVFGDSLADAGQFPDTAGPRGSTLRFTNRVGPTYQDGSGEVFNLNSSTLIG
RMLGVPAGDLAASTSPVNAALGAPDGNNWAVGGYRTDQILDSINSQSTVVDPNTGTLLRSRTGYLPANGFRADPNALYYL
TGGGNDFLQGRVLSASSAAQAANQLADSAQALQQAGARYIMVWLLPDIGKTPALSGSPLASATSALSAGFNQQLVSRLAQ
INAQIIPLNVPLLINEVLAEPARFGFDPNENLVSTCFSGNSCRESTTNGRSSATPNPNRLFFNDRVHPTEAGQRLLADYA
YSLLSAPWEISLLPEMANGTLRMHQDEIRAQWLSDWGNWQGIGQWQSMLSAGGQKMDFDAQDSSADADGRGYNLTIGGSY
RFAENWRTGVVAGAYRQSLEAGPRDSDYKLNSYIATAFLQYQANHWWGDLAVSGGKLDYENAERKFALGVSEGQEKGDTD
GEMWAVSGRVGFDIAGPTSRWHLSPFVSADYAHINVDGYSEKGDRSTALTFSDQTRKSRRAGVGVQGKFQVTPSTQVWGE
VAHEREFETDQQDVTMALNSVQSVGFTLQGYTPQRDLNRATLGVSQKLTQDLTLRGNYNWRKNDDVTQQGVNVALSLSF

Specific function: Unknown

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR017186
- InterPro:   IPR001087
- InterPro:   IPR008265
- InterPro:   IPR006315 [H]

Pfam domain/function: PF03797 Autotransporter; PF00657 Lipase_GDSL [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 68974; Mature: 68843

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSRRWPFAACLLSLACGTAAAAPYSTMVVFGDSLADAGQFPDTAGPRGSTLRFTNRV
CCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCEEEEECCC
GPTYQDGSGEVFNLNSSTLIGRMLGVPAGDLAASTSPVNAALGAPDGNNWAVGGYRTDQI
CCCEECCCCCEEECCCHHHHHHHHCCCCCHHCCCCCCCCEEECCCCCCCEEECCEEHHHH
LDSINSQSTVVDPNTGTLLRSRTGYLPANGFRADPNALYYLTGGGNDFLQGRVLSASSAA
HHHCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHCCEEECCHHHH
QAANQLADSAQALQQAGARYIMVWLLPDIGKTPALSGSPLASATSALSAGFNQQLVSRLA
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
QINAQIIPLNVPLLINEVLAEPARFGFDPNENLVSTCFSGNSCRESTTNGRSSATPNPNR
HCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
LFFNDRVHPTEAGQRLLADYAYSLLSAPWEISLLPEMANGTLRMHQDEIRAQWLSDWGNW
EEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECHHCCCCEEEECHHHHHHHHHHHCCCC
QGIGQWQSMLSAGGQKMDFDAQDSSADADGRGYNLTIGGSYRFAENWRTGVVAGAYRQSL
CCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCEEEHHHHHHH
EAGPRDSDYKLNSYIATAFLQYQANHWWGDLAVSGGKLDYENAERKFALGVSEGQEKGDT
HCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCC
DGEMWAVSGRVGFDIAGPTSRWHLSPFVSADYAHINVDGYSEKGDRSTALTFSDQTRKSR
CCCEEEEECCEEEEECCCCCCEECCCCCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHH
RAGVGVQGKFQVTPSTQVWGEVAHEREFETDQQDVTMALNSVQSVGFTLQGYTPQRDLNR
HCCCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCHHCCH
ATLGVSQKLTQDLTLRGNYNWRKNDDVTQQGVNVALSLSF
HHHCHHHHHHHCEEEECCCCCCCCCCHHHCCCCEEEEECC
>Mature Secondary Structure 
TKTSRRWPFAACLLSLACGTAAAAPYSTMVVFGDSLADAGQFPDTAGPRGSTLRFTNRV
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCEEEEECCC
GPTYQDGSGEVFNLNSSTLIGRMLGVPAGDLAASTSPVNAALGAPDGNNWAVGGYRTDQI
CCCEECCCCCEEECCCHHHHHHHHCCCCCHHCCCCCCCCEEECCCCCCCEEECCEEHHHH
LDSINSQSTVVDPNTGTLLRSRTGYLPANGFRADPNALYYLTGGGNDFLQGRVLSASSAA
HHHCCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHCCEEECCHHHH
QAANQLADSAQALQQAGARYIMVWLLPDIGKTPALSGSPLASATSALSAGFNQQLVSRLA
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
QINAQIIPLNVPLLINEVLAEPARFGFDPNENLVSTCFSGNSCRESTTNGRSSATPNPNR
HCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
LFFNDRVHPTEAGQRLLADYAYSLLSAPWEISLLPEMANGTLRMHQDEIRAQWLSDWGNW
EEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECHHCCCCEEEECHHHHHHHHHHHCCCC
QGIGQWQSMLSAGGQKMDFDAQDSSADADGRGYNLTIGGSYRFAENWRTGVVAGAYRQSL
CCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCEEEHHHHHHH
EAGPRDSDYKLNSYIATAFLQYQANHWWGDLAVSGGKLDYENAERKFALGVSEGQEKGDT
HCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCC
DGEMWAVSGRVGFDIAGPTSRWHLSPFVSADYAHINVDGYSEKGDRSTALTFSDQTRKSR
CCCEEEEECCEEEEECCCCCCEECCCCCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHH
RAGVGVQGKFQVTPSTQVWGEVAHEREFETDQQDVTMALNSVQSVGFTLQGYTPQRDLNR
HCCCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCHHCCH
ATLGVSQKLTQDLTLRGNYNWRKNDDVTQQGVNVALSLSF
HHHCHHHHHHHCEEEECCCCCCCCCCHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10559163; 10984043 [H]