Click here to switch to the map view.

The map label for this gene is ycgM [C]

Identifier: 66047706

GI number: 66047706

Start: 5340942

End: 5341790

Strand: Reverse

Name: ycgM [C]

Synonym: Psyr_4479

Alternate gene names: 66047706

Gene position: 5341790-5340942 (Counterclockwise)

Preceding gene: 66047713

Following gene: 66047704

Centisome position: 87.66

GC content: 61.37

Gene sequence:

>849_bases
ATGAAATTGCTACGTTACGGTGAGAAGGGTCTGGAGAAGCCAGGCGTGCTTGATGCTGCCAACCAGATCCGTGACCTGTC
CGCACACGTCAAGGATATCGCTGGCGATGTGCTGAGCCCTGCAGGTCTTGCAAGCCTGGCTGCGCTGGATCCCGAGAGCC
TGCCTCTGGTTCCGGGCCAGCCACGCATCGGGCCGTGTGTCGGGCAGGTCGGCAAGTTCATCTGCATAGGCTTGAACTAC
GCCGACCACGCAGCCGAGTCGCAGATGGAAGTGCCGAAGGAGCCGATCATCTTCAACAAATGGACCAGCGCAATTTGCGG
CCCCAATGATGATGTCCAGATCCCCCGTGGGTCGCTCAAGACTGACTGGGAGGTCGAGCTGGGCGTGATCATCGGCAAGG
GCGGGCGCTACATCGACGAAGCCGATGCCATGGAGCATGTGGCCGGGTATTGCGTGATCAACGATGTGTCCGAGCGCGAA
TGGCAGCTCGAGCGCGGCGGGACCTGGGACAAGGGTAAAGGCTTCGATACCTTCGGCCCGCTCGGTCCGTGGCTGGTGAC
CCGCGATGAAGTTGCCGACCCTCACTCGCTCGACCTGTGGCTGGAAGTGGATGGCCATCGTTATCAGAATGGCAATACGC
GCACGTTGATTTTCAGCGTGCCGCAACTGATCGCCTACCTGAGCCGGTGCATGAGCCTGCAACCAGGCGATGTCATCTCG
ACGGGGACGCCACCGGGTGTGGGGCAGGGCGTGAAGCCACAACCTGTCTTCCTGCGTGCGGGGCAACGCATACGTCTGGG
GATCGCGGGGCTGGGCGAGCAGAATCAATTGACCGTACAGGCCGACTGA

Upstream 100 bases:

>100_bases
GTTCGGACTTATACGAAAACGTATCGCCGCGCAGGCTGGGCAACAGGGCGTCACCCTCTTGATCCGCGGTTCACACCTTG
GACAGAAACGGGAGAATTCG

Downstream 100 bases:

>100_bases
TCCGCCTCCAGCAGGGAGCCGGCAATCGGCTCCCTGTCACACAAACGATCAGCCCTGCACAAACGTCAGCAGGTCTTTGT
TGAGCGTCTCTGCATGGGTC

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKLLRYGEKGLEKPGVLDAANQIRDLSAHVKDIAGDVLSPAGLASLAALDPESLPLVPGQPRIGPCVGQVGKFICIGLNY
ADHAAESQMEVPKEPIIFNKWTSAICGPNDDVQIPRGSLKTDWEVELGVIIGKGGRYIDEADAMEHVAGYCVINDVSERE
WQLERGGTWDKGKGFDTFGPLGPWLVTRDEVADPHSLDLWLEVDGHRYQNGNTRTLIFSVPQLIAYLSRCMSLQPGDVIS
TGTPPGVGQGVKPQPVFLRAGQRIRLGIAGLGEQNQLTVQAD

Sequences:

>Translated_282_residues
MKLLRYGEKGLEKPGVLDAANQIRDLSAHVKDIAGDVLSPAGLASLAALDPESLPLVPGQPRIGPCVGQVGKFICIGLNY
ADHAAESQMEVPKEPIIFNKWTSAICGPNDDVQIPRGSLKTDWEVELGVIIGKGGRYIDEADAMEHVAGYCVINDVSERE
WQLERGGTWDKGKGFDTFGPLGPWLVTRDEVADPHSLDLWLEVDGHRYQNGNTRTLIFSVPQLIAYLSRCMSLQPGDVIS
TGTPPGVGQGVKPQPVFLRAGQRIRLGIAGLGEQNQLTVQAD
>Mature_282_residues
MKLLRYGEKGLEKPGVLDAANQIRDLSAHVKDIAGDVLSPAGLASLAALDPESLPLVPGQPRIGPCVGQVGKFICIGLNY
ADHAAESQMEVPKEPIIFNKWTSAICGPNDDVQIPRGSLKTDWEVELGVIIGKGGRYIDEADAMEHVAGYCVINDVSERE
WQLERGGTWDKGKGFDTFGPLGPWLVTRDEVADPHSLDLWLEVDGHRYQNGNTRTLIFSVPQLIAYLSRCMSLQPGDVIS
TGTPPGVGQGVKPQPVFLRAGQRIRLGIAGLGEQNQLTVQAD

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=202, Percent_Identity=53.4653465346535, Blast_Score=222, Evalue=3e-58,
Organism=Homo sapiens, GI40786394, Length=202, Percent_Identity=52.4752475247525, Blast_Score=215, Evalue=3e-56,
Organism=Homo sapiens, GI215422413, Length=210, Percent_Identity=37.1428571428571, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI66348062, Length=202, Percent_Identity=38.1188118811881, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=38.1188118811881, Blast_Score=139, Evalue=2e-33,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=37.9120879120879, Blast_Score=124, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17557057, Length=201, Percent_Identity=33.8308457711443, Blast_Score=128, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=218, Percent_Identity=31.651376146789, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28572127, Length=288, Percent_Identity=41.6666666666667, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI28571789, Length=215, Percent_Identity=39.5348837209302, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24663695, Length=220, Percent_Identity=34.5454545454545, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30484; Mature: 30484

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRYGEKGLEKPGVLDAANQIRDLSAHVKDIAGDVLSPAGLASLAALDPESLPLVPGQ
CCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
PRIGPCVGQVGKFICIGLNYADHAAESQMEVPKEPIIFNKWTSAICGPNDDVQIPRGSLK
CCCCHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCEEEECCHHHHCCCCCCCCCCCCCCC
TDWEVELGVIIGKGGRYIDEADAMEHVAGYCVINDVSEREWQLERGGTWDKGKGFDTFGP
CCCEEEEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCCEEHHCCCCCCCCCCCCCCCC
LGPWLVTRDEVADPHSLDLWLEVDGHRYQNGNTRTLIFSVPQLIAYLSRCMSLQPGDVIS
CCCEEEEHHCCCCCCCEEEEEEECCEEECCCCEEEEEEEHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGQGVKPQPVFLRAGQRIRLGIAGLGEQNQLTVQAD
CCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MKLLRYGEKGLEKPGVLDAANQIRDLSAHVKDIAGDVLSPAGLASLAALDPESLPLVPGQ
CCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
PRIGPCVGQVGKFICIGLNYADHAAESQMEVPKEPIIFNKWTSAICGPNDDVQIPRGSLK
CCCCHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCEEEECCHHHHCCCCCCCCCCCCCCC
TDWEVELGVIIGKGGRYIDEADAMEHVAGYCVINDVSEREWQLERGGTWDKGKGFDTFGP
CCCEEEEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCCEEHHCCCCCCCCCCCCCCCC
LGPWLVTRDEVADPHSLDLWLEVDGHRYQNGNTRTLIFSVPQLIAYLSRCMSLQPGDVIS
CCCEEEEHHCCCCCCCEEEEEEECCEEECCCCEEEEEEEHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGQGVKPQPVFLRAGQRIRLGIAGLGEQNQLTVQAD
CCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA