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The map label for this gene is dacC [H]

Identifier: 66047588

GI number: 66047588

Start: 5213965

End: 5215152

Strand: Reverse

Name: dacC [H]

Synonym: Psyr_4361

Alternate gene names: 66047588

Gene position: 5215152-5213965 (Counterclockwise)

Preceding gene: 66047589

Following gene: 66047587

Centisome position: 85.58

GC content: 58.75

Gene sequence:

>1188_bases
TTGCCCATTAGGATTCTCGAGAGACGGATGAACATCACCACCTTTGCAAAACGTTTGTGCCTGCTTGTTCCACTGATTAT
CACCCCGACTGTGTGGGCGGCAGAGCAGATGACGCCTGCTGCACCGCAACTGGCGGCCAAGTCCTACGTGCTGATGGATG
CCACCAGTGGCAACGTCCTGGTCGAGAACAATGGTGATCAGCGTCTGGCTCCTGCCAGCCTGACCAAGCTGATGACCGCC
TACATCGCGACCCTGGAAATCCGTCGCGGCCAGATCGGCGAAAACGATCCGGTGACGATCAGTGAAAACGCCTGGCGCAC
AGGCGGTTCGCGGATGTTCATCAAGGTCGGCAGCCAGGTCACGGTCAGCGACCTGTTGCACGGCATCATCATCCAGTCGG
GTAACGACGCCAGTGTCGCGATCTCCGAGCACATCGCCGGCAGCGAAGACGCCTTCGCCGACATGATGAACAAGACTGCC
GGCGACCTGGGCATGACCAACAGCCACTTCATGAACCCGACCGGTCTGCCGAACCCTGAGCACTACTCGTCGGCTCACGA
CATGGCGATCCTGGCACGCGCGATCATTCACGAGGACCCGGCCCACTATGCGATCTACTCGCAGAAGGAGTTCTTCTGGA
ACGGCATCAAACAGCCTAACCGTAACCTGCTGCTGTGGCGCGACAAGACCGTTGACGGTCTGAAAACCGGTCACACCGAT
GAAGCCGGCTACTGCATGGTGTCCTCGGCAGTACGTGACGGCATGCGCCTGATCGCCGTGGTGTTCGGCACCAACAGCGA
ACAGGCCCGTGCGGCGGAAACCCAGAAGCTGCTGACCTATGGCTTCCGTTTCTTCGAAACCCAGAACTTCTATCAGAAGG
GCACCGAGCTGGCCCAGGCCACGGTCTGGAAAGGCACCGAGCGTCAGGTCAAGGCCGGTCTGGCTGAAGATCTGAGCATG
ACCATGCCAAAAGGCGACATGAAGAAGCTGTCTGCCAGCATGACCATGAACCCGCAACTGGTTGCGCCAATCGCCAAGGG
CGACGTGATCGGCAAGGTCGAGGTCAAGAAAGACGATCAGGTGGTTCACACCGCCAATCTGATTGCGCTCGATGGGGTTG
AGGAAGGTGGTATTTTCCGCCGCGTGTGGGATAGCATCCGCCTGTTCTTCTACGGCTTGTTCAACTGA

Upstream 100 bases:

>100_bases
ACAGGCGACTTTGTCAGCCAGGGTTACAGCCTGGCGCCACGAGCCGTACCGAAGCGTTTTCGCTTCGCCGGTCTGTTCAG
TTTTGCCCGCAAGGGCATGT

Downstream 100 bases:

>100_bases
TCCAGTAACCAATGCCGACCTTCTCGCGGCCTGCTCATGATCTGAGCGGGCCGCGTGTCCGTCGTCACGGCTTGTGAGAC
CTTTACTGCCATGACTGATA

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPIRILERRMNITTFAKRLCLLVPLIITPTVWAAEQMTPAAPQLAAKSYVLMDATSGNVLVENNGDQRLAPASLTKLMTA
YIATLEIRRGQIGENDPVTISENAWRTGGSRMFIKVGSQVTVSDLLHGIIIQSGNDASVAISEHIAGSEDAFADMMNKTA
GDLGMTNSHFMNPTGLPNPEHYSSAHDMAILARAIIHEDPAHYAIYSQKEFFWNGIKQPNRNLLLWRDKTVDGLKTGHTD
EAGYCMVSSAVRDGMRLIAVVFGTNSEQARAAETQKLLTYGFRFFETQNFYQKGTELAQATVWKGTERQVKAGLAEDLSM
TMPKGDMKKLSASMTMNPQLVAPIAKGDVIGKVEVKKDDQVVHTANLIALDGVEEGGIFRRVWDSIRLFFYGLFN

Sequences:

>Translated_395_residues
MPIRILERRMNITTFAKRLCLLVPLIITPTVWAAEQMTPAAPQLAAKSYVLMDATSGNVLVENNGDQRLAPASLTKLMTA
YIATLEIRRGQIGENDPVTISENAWRTGGSRMFIKVGSQVTVSDLLHGIIIQSGNDASVAISEHIAGSEDAFADMMNKTA
GDLGMTNSHFMNPTGLPNPEHYSSAHDMAILARAIIHEDPAHYAIYSQKEFFWNGIKQPNRNLLLWRDKTVDGLKTGHTD
EAGYCMVSSAVRDGMRLIAVVFGTNSEQARAAETQKLLTYGFRFFETQNFYQKGTELAQATVWKGTERQVKAGLAEDLSM
TMPKGDMKKLSASMTMNPQLVAPIAKGDVIGKVEVKKDDQVVHTANLIALDGVEEGGIFRRVWDSIRLFFYGLFN
>Mature_394_residues
PIRILERRMNITTFAKRLCLLVPLIITPTVWAAEQMTPAAPQLAAKSYVLMDATSGNVLVENNGDQRLAPASLTKLMTAY
IATLEIRRGQIGENDPVTISENAWRTGGSRMFIKVGSQVTVSDLLHGIIIQSGNDASVAISEHIAGSEDAFADMMNKTAG
DLGMTNSHFMNPTGLPNPEHYSSAHDMAILARAIIHEDPAHYAIYSQKEFFWNGIKQPNRNLLLWRDKTVDGLKTGHTDE
AGYCMVSSAVRDGMRLIAVVFGTNSEQARAAETQKLLTYGFRFFETQNFYQKGTELAQATVWKGTERQVKAGLAEDLSMT
MPKGDMKKLSASMTMNPQLVAPIAKGDVIGKVEVKKDDQVVHTANLIALDGVEEGGIFRRVWDSIRLFFYGLFN

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=378, Percent_Identity=44.973544973545, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI1786851, Length=393, Percent_Identity=44.529262086514, Blast_Score=322, Evalue=2e-89,
Organism=Escherichia coli, GI87082022, Length=382, Percent_Identity=40.8376963350785, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI87082054, Length=285, Percent_Identity=28.0701754385965, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43561; Mature: 43429

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRILERRMNITTFAKRLCLLVPLIITPTVWAAEQMTPAAPQLAAKSYVLMDATSGNVL
CCHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHCCCEEEEEECCCCEE
VENNGDQRLAPASLTKLMTAYIATLEIRRGQIGENDPVTISENAWRTGGSRMFIKVGSQV
EECCCCCEECHHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCE
TVSDLLHGIIIQSGNDASVAISEHIAGSEDAFADMMNKTAGDLGMTNSHFMNPTGLPNPE
EHHHHHHEEEEECCCCCEEEEEHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
HYSSAHDMAILARAIIHEDPAHYAIYSQKEFFWNGIKQPNRNLLLWRDKTVDGLKTGHTD
HCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCC
EAGYCMVSSAVRDGMRLIAVVFGTNSEQARAAETQKLLTYGFRFFETQNFYQKGTELAQA
CCCCEEEHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVWKGTERQVKAGLAEDLSMTMPKGDMKKLSASMTMNPQLVAPIAKGDVIGKVEVKKDDQ
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCC
VVHTANLIALDGVEEGGIFRRVWDSIRLFFYGLFN
EEEEEEEEEECCCCCCCHHHHHHHHHHHHHEEECC
>Mature Secondary Structure 
PIRILERRMNITTFAKRLCLLVPLIITPTVWAAEQMTPAAPQLAAKSYVLMDATSGNVL
CHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHCCCEEEEEECCCCEE
VENNGDQRLAPASLTKLMTAYIATLEIRRGQIGENDPVTISENAWRTGGSRMFIKVGSQV
EECCCCCEECHHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCE
TVSDLLHGIIIQSGNDASVAISEHIAGSEDAFADMMNKTAGDLGMTNSHFMNPTGLPNPE
EHHHHHHEEEEECCCCCEEEEEHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
HYSSAHDMAILARAIIHEDPAHYAIYSQKEFFWNGIKQPNRNLLLWRDKTVDGLKTGHTD
HCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCC
EAGYCMVSSAVRDGMRLIAVVFGTNSEQARAAETQKLLTYGFRFFETQNFYQKGTELAQA
CCCCEEEHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVWKGTERQVKAGLAEDLSMTMPKGDMKKLSASMTMNPQLVAPIAKGDVIGKVEVKKDDQ
HHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCC
VVHTANLIALDGVEEGGIFRRVWDSIRLFFYGLFN
EEEEEEEEEECCCCCCCHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]