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The map label for this gene is yisV [H]

Identifier: 66047552

GI number: 66047552

Start: 5177347

End: 5178687

Strand: Direct

Name: yisV [H]

Synonym: Psyr_4325

Alternate gene names: 66047552

Gene position: 5177347-5178687 (Clockwise)

Preceding gene: 66047545

Following gene: 66047555

Centisome position: 84.96

GC content: 56.23

Gene sequence:

>1341_bases
ATGAGCGTTGATGCCCTTTATGACTCGCTGAAACAGCGCCTTGAATCAGGCGAGTGGCTGGCTGGACAACGTATGCCGTC
GATAAGGAAGCTGGCCTTGACTGCCGAAGCGAGCTACCACGATGCCGTCTCGGCCTATGCTCGCCTGGTGAGTGAAGGTG
TGCTGTCGGCTTCTCCCGGACGCGGTTACTTTGTGAGCAGTCATGTCACCCATGTGGATAACGTGCGGGAAATAGAGTGC
ATGAGCGCCGACCCACTGTTCAGGCTGCTACAGGCAGGGCCGCACTACACCAAGCTGGGATGTGGCTGGCTGCCACCGGC
ATGGCGAGATACCGAATTGCTGGCCAAGGCCATTCGACGCACGGCGCGGCTGGAGCAAAGTTCGCTGGCCGAATACGGCG
ACATTTCCGGCTATCTCCCGATGCGTAAACAGCTTTGCGTTCACCTGAAGCGTCTCACCCGTATCGACATCAGACCCAGT
CAGATCCTCACCACCCTGGGAGCAACGCAGGGCCTGGATCTGGTTGCCCGCCTATTGATCAAGCCCGGTGACCATGTATT
CGTGGACGAGCCGGGCAATGGCAACCTGATCAGGTTGATTCAGTTGGCGGGCGGACATGTTGTGGGTATAAAGCGGACTC
AGGACGGGACGGACATTGCCGAGATGGAGAGTTATCTGGCGAAGCACACGGTCAAAGCGTTCTTCTGCAATAGCACCTTC
CACAATCCGACCGGCAGCAACATCAGCCCGCACAATGCTTTCAAGGTTCTGCGTCTTGCTGTAGAGCACGAGTTCTTTGT
GGTCGAAGATGATGCCTATGGTGACTTCAGCCCCACTGTCCGCCAGACGTTTGCCGAACTGGATAATCTGGATCGTGTGA
TCTACGTCGGCAGTTTTTCCAAATGCCTTTCTGCTTCGCTGCGCGTGGGTTATATCGCCTGCTCGCAAGAGCTCATCGAG
CCGCTGACACGCTTGAAACTCCTGACATGCGTTGCCGTTCCAGCGTTCTGCGAGCGGTTCGTCAACACCATTCTTGCGGA
CGGTACTTATGCCCGGCACATGCAGGATGTTCAACAGAGGCTTATCAGCCAGCAGGTCCAGACTCAACGCGCCCTGCGAG
CAAGAGGCTGGCAATTCGATATAGCACCGCAGGGCGGCATGTTCATCTGGGCCTATCACTCGGACATCCCTAACCTGGAG
CCCTTCATAAAGAAACTTGAACAACACAAGATCCTGCTGATGCCGGGCTCGGCGTTCTCGGTGTCGCGCGACTACCAGCG
TTTTGCGCGAATAAACTGCACGCATTTTTCCGAGGCAATAGAAGAACGCTTTTCAGTGTGA

Upstream 100 bases:

>100_bases
CAAGCGCATAATCGCACTCACCCACCCCACAAGCGCGCACAGTCGACAAGCTTTACAGTTAACTGTTAGGGTGTTTTTCC
TATCAGTTTGCCGGGTGCTT

Downstream 100 bases:

>100_bases
TCAACGAAGAGCAGCGTTTAGTTATCGGGGCTACTTGCGCGTGGAGCCCACTGCTCAATAACACTGCCGCCAGCATGCCT
CACGCCGAAAAGTCAGGTCT

Product: transcriptional regulator GntR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSVDALYDSLKQRLESGEWLAGQRMPSIRKLALTAEASYHDAVSAYARLVSEGVLSASPGRGYFVSSHVTHVDNVREIEC
MSADPLFRLLQAGPHYTKLGCGWLPPAWRDTELLAKAIRRTARLEQSSLAEYGDISGYLPMRKQLCVHLKRLTRIDIRPS
QILTTLGATQGLDLVARLLIKPGDHVFVDEPGNGNLIRLIQLAGGHVVGIKRTQDGTDIAEMESYLAKHTVKAFFCNSTF
HNPTGSNISPHNAFKVLRLAVEHEFFVVEDDAYGDFSPTVRQTFAELDNLDRVIYVGSFSKCLSASLRVGYIACSQELIE
PLTRLKLLTCVAVPAFCERFVNTILADGTYARHMQDVQQRLISQQVQTQRALRARGWQFDIAPQGGMFIWAYHSDIPNLE
PFIKKLEQHKILLMPGSAFSVSRDYQRFARINCTHFSEAIEERFSV

Sequences:

>Translated_446_residues
MSVDALYDSLKQRLESGEWLAGQRMPSIRKLALTAEASYHDAVSAYARLVSEGVLSASPGRGYFVSSHVTHVDNVREIEC
MSADPLFRLLQAGPHYTKLGCGWLPPAWRDTELLAKAIRRTARLEQSSLAEYGDISGYLPMRKQLCVHLKRLTRIDIRPS
QILTTLGATQGLDLVARLLIKPGDHVFVDEPGNGNLIRLIQLAGGHVVGIKRTQDGTDIAEMESYLAKHTVKAFFCNSTF
HNPTGSNISPHNAFKVLRLAVEHEFFVVEDDAYGDFSPTVRQTFAELDNLDRVIYVGSFSKCLSASLRVGYIACSQELIE
PLTRLKLLTCVAVPAFCERFVNTILADGTYARHMQDVQQRLISQQVQTQRALRARGWQFDIAPQGGMFIWAYHSDIPNLE
PFIKKLEQHKILLMPGSAFSVSRDYQRFARINCTHFSEAIEERFSV
>Mature_445_residues
SVDALYDSLKQRLESGEWLAGQRMPSIRKLALTAEASYHDAVSAYARLVSEGVLSASPGRGYFVSSHVTHVDNVREIECM
SADPLFRLLQAGPHYTKLGCGWLPPAWRDTELLAKAIRRTARLEQSSLAEYGDISGYLPMRKQLCVHLKRLTRIDIRPSQ
ILTTLGATQGLDLVARLLIKPGDHVFVDEPGNGNLIRLIQLAGGHVVGIKRTQDGTDIAEMESYLAKHTVKAFFCNSTFH
NPTGSNISPHNAFKVLRLAVEHEFFVVEDDAYGDFSPTVRQTFAELDNLDRVIYVGSFSKCLSASLRVGYIACSQELIEP
LTRLKLLTCVAVPAFCERFVNTILADGTYARHMQDVQQRLISQQVQTQRALRARGWQFDIAPQGGMFIWAYHSDIPNLEP
FIKKLEQHKILLMPGSAFSVSRDYQRFARINCTHFSEAIEERFSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=303, Percent_Identity=26.7326732673267, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI33469970, Length=303, Percent_Identity=26.7326732673267, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1787710, Length=444, Percent_Identity=23.8738738738739, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1790797, Length=450, Percent_Identity=23.7777777777778, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6321236, Length=262, Percent_Identity=22.1374045801527, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356535, Length=346, Percent_Identity=23.6994219653179, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 50045; Mature: 49914

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50949 HTH_GNTR ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDALYDSLKQRLESGEWLAGQRMPSIRKLALTAEASYHDAVSAYARLVSEGVLSASPG
CCHHHHHHHHHHHHCCCCEECCCCCCHHHHHEEECCCCHHHHHHHHHHHHHHCCCCCCCC
RGYFVSSHVTHVDNVREIECMSADPLFRLLQAGPHYTKLGCGWLPPAWRDTELLAKAIRR
CCEEEECCCHHHCCCHHEEECCCCHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHH
TARLEQSSLAEYGDISGYLPMRKQLCVHLKRLTRIDIRPSQILTTLGATQGLDLVARLLI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
KPGDHVFVDEPGNGNLIRLIQLAGGHVVGIKRTQDGTDIAEMESYLAKHTVKAFFCNSTF
CCCCEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCC
HNPTGSNISPHNAFKVLRLAVEHEFFVVEDDAYGDFSPTVRQTFAELDNLDRVIYVGSFS
CCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHH
KCLSASLRVGYIACSQELIEPLTRLKLLTCVAVPAFCERFVNTILADGTYARHMQDVQQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LISQQVQTQRALRARGWQFDIAPQGGMFIWAYHSDIPNLEPFIKKLEQHKILLMPGSAFS
HHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCH
VSRDYQRFARINCTHFSEAIEERFSV
HHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVDALYDSLKQRLESGEWLAGQRMPSIRKLALTAEASYHDAVSAYARLVSEGVLSASPG
CHHHHHHHHHHHHCCCCEECCCCCCHHHHHEEECCCCHHHHHHHHHHHHHHCCCCCCCC
RGYFVSSHVTHVDNVREIECMSADPLFRLLQAGPHYTKLGCGWLPPAWRDTELLAKAIRR
CCEEEECCCHHHCCCHHEEECCCCHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHH
TARLEQSSLAEYGDISGYLPMRKQLCVHLKRLTRIDIRPSQILTTLGATQGLDLVARLLI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
KPGDHVFVDEPGNGNLIRLIQLAGGHVVGIKRTQDGTDIAEMESYLAKHTVKAFFCNSTF
CCCCEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCC
HNPTGSNISPHNAFKVLRLAVEHEFFVVEDDAYGDFSPTVRQTFAELDNLDRVIYVGSFS
CCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHH
KCLSASLRVGYIACSQELIEPLTRLKLLTCVAVPAFCERFVNTILADGTYARHMQDVQQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LISQQVQTQRALRARGWQFDIAPQGGMFIWAYHSDIPNLEPFIKKLEQHKILLMPGSAFS
HHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCH
VSRDYQRFARINCTHFSEAIEERFSV
HHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]