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The map label for this gene is dsdC [H]

Identifier: 66047545

GI number: 66047545

Start: 5168966

End: 5169964

Strand: Direct

Name: dsdC [H]

Synonym: Psyr_4318

Alternate gene names: 66047545

Gene position: 5168966-5169964 (Clockwise)

Preceding gene: 66047532

Following gene: 66047552

Centisome position: 84.82

GC content: 49.35

Gene sequence:

>999_bases
GTGCTGGCTAATATGTTTTCAAAAATCCCCTTAACGTCTCTACGATCGTTCGAGTCAGCGGCTCGACTAAGCAGCTTCAA
AGCGGCTGCCATTGAACTTTTTGTTACTCCTTCAGCGATTTCACATCAAGTAAAATCACTAGAACACTGGCTCGGCTTAT
TGCTTTTTGAGCGAGTAGCCAAGGGAGTCACCCTAACGACTGAAGGGCTTGATTTATACAAGAATATCCATCAGCATTTT
TCAAGCATAAACCAAAGTCTTAGTCAACTACGCTCACAGACCGACGAGAACGCAATCACCGTCACAACCACCCATGCATT
TGCCTCATTGTGGCTCATTCCCAGATTAGGAGATTTCTACCGCCGCCATCCAACGATGCAAGTCAACATCATCACCAGCA
AAACACAGGCAGACCTGCACAGAGATGCCAGTATCGACGTGGCTATTAGCAGCGTTTTCAAAGAGGTCCCTGATACCTAT
CAGCTACATCTAATGGACGAAAGCTTTCTGGCCTATATGCCCTGCAGGACGCCCTTATCTGGAGACACAAGGTCCCCACT
CATCAACGTTCGTTGGGAGGCTGATGGCCATAACCCATTCGACTGGACGACTTGGTGCCAAGCGGCGGGACACGACGATT
GGCTGGCCAACGCCACGTTCAGGGAGTACGACGATGAACATCATGCTTTGCAAGCTGCAACTTCTGGCTATGGGATGGTG
CTCGCCAGCGACGTCTTAGCCGTCGACAGTGTTACCCGAGGCTTTTTAACGCCATACAAGCCCGAGGTTAAACTAACGGG
GACCCATTATATCTCGGCCTGTGTACCTGGCAGAGAACGAAATCCGCCCGTCAGGTACTTCCTTGACTGGCTCAGTAAAG
AAGCCTCTAAACATCTTGTACTGCAACGCCTCCTCACAGAGTCCATAGACTTTAGCGCACACAAAAATCCATTGAGGAAC
GACCGGAATCAAAGCATGCTCAAGCTCCAGATATACTAA

Upstream 100 bases:

>100_bases
GGATTGGTGTACGGCTTTACGGGGACAAGTCCACGGCAAGATTGACATACCAAAATAACCGGATAAACACTATAGCCCAT
GTATTCGCCCAAACAATGGA

Downstream 100 bases:

>100_bases
CAATGAGACTGGGAGTTCGATGCTCTGCCCCCCCATCGATGGCGATGGAGACCACGTAGATAGGCATAAATCGCCATTTG
CCATCAGGCAGTGACAAGTC

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLANMFSKIPLTSLRSFESAARLSSFKAAAIELFVTPSAISHQVKSLEHWLGLLLFERVAKGVTLTTEGLDLYKNIHQHF
SSINQSLSQLRSQTDENAITVTTTHAFASLWLIPRLGDFYRRHPTMQVNIITSKTQADLHRDASIDVAISSVFKEVPDTY
QLHLMDESFLAYMPCRTPLSGDTRSPLINVRWEADGHNPFDWTTWCQAAGHDDWLANATFREYDDEHHALQAATSGYGMV
LASDVLAVDSVTRGFLTPYKPEVKLTGTHYISACVPGRERNPPVRYFLDWLSKEASKHLVLQRLLTESIDFSAHKNPLRN
DRNQSMLKLQIY

Sequences:

>Translated_332_residues
MLANMFSKIPLTSLRSFESAARLSSFKAAAIELFVTPSAISHQVKSLEHWLGLLLFERVAKGVTLTTEGLDLYKNIHQHF
SSINQSLSQLRSQTDENAITVTTTHAFASLWLIPRLGDFYRRHPTMQVNIITSKTQADLHRDASIDVAISSVFKEVPDTY
QLHLMDESFLAYMPCRTPLSGDTRSPLINVRWEADGHNPFDWTTWCQAAGHDDWLANATFREYDDEHHALQAATSGYGMV
LASDVLAVDSVTRGFLTPYKPEVKLTGTHYISACVPGRERNPPVRYFLDWLSKEASKHLVLQRLLTESIDFSAHKNPLRN
DRNQSMLKLQIY
>Mature_332_residues
MLANMFSKIPLTSLRSFESAARLSSFKAAAIELFVTPSAISHQVKSLEHWLGLLLFERVAKGVTLTTEGLDLYKNIHQHF
SSINQSLSQLRSQTDENAITVTTTHAFASLWLIPRLGDFYRRHPTMQVNIITSKTQADLHRDASIDVAISSVFKEVPDTY
QLHLMDESFLAYMPCRTPLSGDTRSPLINVRWEADGHNPFDWTTWCQAAGHDDWLANATFREYDDEHHALQAATSGYGMV
LASDVLAVDSVTRGFLTPYKPEVKLTGTHYISACVPGRERNPPVRYFLDWLSKEASKHLVLQRLLTESIDFSAHKNPLRN
DRNQSMLKLQIY

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=297, Percent_Identity=29.2929292929293, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789173, Length=297, Percent_Identity=31.986531986532, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786448, Length=286, Percent_Identity=29.7202797202797, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787128, Length=134, Percent_Identity=29.8507462686567, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789440, Length=148, Percent_Identity=29.0540540540541, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37607; Mature: 37607

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANMFSKIPLTSLRSFESAARLSSFKAAAIELFVTPSAISHQVKSLEHWLGLLLFERVA
CCCHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
KGVTLTTEGLDLYKNIHQHFSSINQSLSQLRSQTDENAITVTTTHAFASLWLIPRLGDFY
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHH
RRHPTMQVNIITSKTQADLHRDASIDVAISSVFKEVPDTYQLHLMDESFLAYMPCRTPLS
HHCCCEEEEEEECCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHEEECCCCCCC
GDTRSPLINVRWEADGHNPFDWTTWCQAAGHDDWLANATFREYDDEHHALQAATSGYGMV
CCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCHHCCCHHHHCCCHHHHHHHHCCCCCHH
LASDVLAVDSVTRGFLTPYKPEVKLTGTHYISACVPGRERNPPVRYFLDWLSKEASKHLV
HHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LQRLLTESIDFSAHKNPLRNDRNQSMLKLQIY
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MLANMFSKIPLTSLRSFESAARLSSFKAAAIELFVTPSAISHQVKSLEHWLGLLLFERVA
CCCHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
KGVTLTTEGLDLYKNIHQHFSSINQSLSQLRSQTDENAITVTTTHAFASLWLIPRLGDFY
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHH
RRHPTMQVNIITSKTQADLHRDASIDVAISSVFKEVPDTYQLHLMDESFLAYMPCRTPLS
HHCCCEEEEEEECCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHEEECCCCCCC
GDTRSPLINVRWEADGHNPFDWTTWCQAAGHDDWLANATFREYDDEHHALQAATSGYGMV
CCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCHHCCCHHHHCCCHHHHHHHHCCCCCHH
LASDVLAVDSVTRGFLTPYKPEVKLTGTHYISACVPGRERNPPVRYFLDWLSKEASKHLV
HHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LQRLLTESIDFSAHKNPLRNDRNQSMLKLQIY
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]