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The map label for this gene is 66047522

Identifier: 66047522

GI number: 66047522

Start: 5121325

End: 5122242

Strand: Direct

Name: 66047522

Synonym: Psyr_4295

Alternate gene names: NA

Gene position: 5121325-5122242 (Clockwise)

Preceding gene: 66047518

Following gene: 66047523

Centisome position: 84.04

GC content: 61.66

Gene sequence:

>918_bases
ATGTCCCTACCGCTTATCTACCATGAAGACTACAGCCCGGACTTCCCGGCGGATCATCGCTTCCCGATGGACAAGTTTCG
TTTGTTGCGCGATTACTTGATCGACAGCGGCCTGACCAGTGACGTTCAATTAATGCGTCCCGAGTTGTGCCCGGCGGACA
TTCTGGCGCTGGCTCATGATCCGTCCTACATCAGCCGCTACCTTAGCGGTGATCTGTCGCGCGAAGACCAGCGGCGTCTC
GGACTGCCGTGGAGCGAGGCTCTGGCACGCCGAACCATCCGTGCGGTAGGCGGCTCACTGCTGACCGCCGAACAGGCCCT
CAAGCATGGCCTGGCCTGCCACCTGGCGGGCGGCACCCACCATGCGCACTATGACTACCCGGCGGGTTTCTGCATTTTCA
ATGACCTGGCGGTGATCAGTCAGTACCTGCTGCAAAGCGGCCGCGTGGACAAGGTGCTGATCTTTGACTGCGATGTGCAT
CAGGGTGACGGCACGGCGCGCATTCTGGCCGATACCGAGGACGCCATTACCGTCTCGCTGCACTGCGAAAAGAACTTCCC
GGCACGCAAGGCGCAGAGCGACTGGGACATCCCGCTGCCGATGGGCATGGGCGACGCCGACTACCTGAACGTCGTCGATG
ACCTGCTCAACTACCTGCTGCCGCTCTATAAGCCGGACCTGGTGCTGTATGACGCAGGCGTCGATGTCCACAAGGACGAT
GCGCTGGGCTATCTGCAACTCACCGACCAGGGGCTGGCCAATCGCGACGAAGCGGTGCTGCGTCATTGCCTGAGCCGCGA
CATTCCGGTCATGGGCGTGATCGGCGGTGGCTACAGCAAGGACCGCTTGGCACTGGCAAGGCGCCACGGAATCCTCCATC
ACAGTGCGCAACGGGTCTGGAACGACATGGGCCTGTGA

Upstream 100 bases:

>100_bases
ACATGAATGGGCGTCAGTGCAGCCATCCGCTGCGCCACACAACTGGGCGTACGGATGCTTTACTGGCACTATCGGGCTTC
CGCCCTCTAACGGACGCAAA

Downstream 100 bases:

>100_bases
GCCTGCGCGGTACTTCGCTTCAGTCTCCGCCAATGACGTGCGCCACACCTTGAAAGAACGCTCGGGTAGAATGCCCCACC
CCTCTGCTATCGATACTTCG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSLPLIYHEDYSPDFPADHRFPMDKFRLLRDYLIDSGLTSDVQLMRPELCPADILALAHDPSYISRYLSGDLSREDQRRL
GLPWSEALARRTIRAVGGSLLTAEQALKHGLACHLAGGTHHAHYDYPAGFCIFNDLAVISQYLLQSGRVDKVLIFDCDVH
QGDGTARILADTEDAITVSLHCEKNFPARKAQSDWDIPLPMGMGDADYLNVVDDLLNYLLPLYKPDLVLYDAGVDVHKDD
ALGYLQLTDQGLANRDEAVLRHCLSRDIPVMGVIGGGYSKDRLALARRHGILHHSAQRVWNDMGL

Sequences:

>Translated_305_residues
MSLPLIYHEDYSPDFPADHRFPMDKFRLLRDYLIDSGLTSDVQLMRPELCPADILALAHDPSYISRYLSGDLSREDQRRL
GLPWSEALARRTIRAVGGSLLTAEQALKHGLACHLAGGTHHAHYDYPAGFCIFNDLAVISQYLLQSGRVDKVLIFDCDVH
QGDGTARILADTEDAITVSLHCEKNFPARKAQSDWDIPLPMGMGDADYLNVVDDLLNYLLPLYKPDLVLYDAGVDVHKDD
ALGYLQLTDQGLANRDEAVLRHCLSRDIPVMGVIGGGYSKDRLALARRHGILHHSAQRVWNDMGL
>Mature_304_residues
SLPLIYHEDYSPDFPADHRFPMDKFRLLRDYLIDSGLTSDVQLMRPELCPADILALAHDPSYISRYLSGDLSREDQRRLG
LPWSEALARRTIRAVGGSLLTAEQALKHGLACHLAGGTHHAHYDYPAGFCIFNDLAVISQYLLQSGRVDKVLIFDCDVHQ
GDGTARILADTEDAITVSLHCEKNFPARKAQSDWDIPLPMGMGDADYLNVVDDLLNYLLPLYKPDLVLYDAGVDVHKDDA
LGYLQLTDQGLANRDEAVLRHCLSRDIPVMGVIGGGYSKDRLALARRHGILHHSAQRVWNDMGL

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=311, Percent_Identity=25.7234726688103, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI209862883, Length=272, Percent_Identity=27.5735294117647, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI13128860, Length=282, Percent_Identity=27.3049645390071, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI8923769, Length=295, Percent_Identity=26.1016949152542, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI293336691, Length=257, Percent_Identity=27.2373540856031, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI13128864, Length=177, Percent_Identity=31.638418079096, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20070354, Length=325, Percent_Identity=27.3846153846154, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI13128862, Length=216, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI169234807, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI148539870, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI62750349, Length=248, Percent_Identity=26.6129032258064, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI62750347, Length=248, Percent_Identity=26.6129032258064, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI30795202, Length=174, Percent_Identity=30.4597701149425, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI30795204, Length=174, Percent_Identity=30.4597701149425, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI17158039, Length=174, Percent_Identity=30.4597701149425, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI153085395, Length=174, Percent_Identity=30.4597701149425, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI262073092, Length=217, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=308, Percent_Identity=27.5974025974026, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17537347, Length=260, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=282, Percent_Identity=25.177304964539, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=277, Percent_Identity=25.2707581227437, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540334, Length=150, Percent_Identity=31.3333333333333, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540332, Length=150, Percent_Identity=31.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193206283, Length=150, Percent_Identity=31.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25154020, Length=278, Percent_Identity=25.1798561151079, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25154022, Length=278, Percent_Identity=24.4604316546763, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534739, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193209491, Length=231, Percent_Identity=24.6753246753247, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323999, Length=293, Percent_Identity=26.962457337884, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=26.7361111111111, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324307, Length=208, Percent_Identity=27.4038461538462, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325325, Length=173, Percent_Identity=28.9017341040462, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281360899, Length=279, Percent_Identity=28.673835125448, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642144, Length=279, Percent_Identity=28.673835125448, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24642146, Length=279, Percent_Identity=28.673835125448, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24642142, Length=279, Percent_Identity=28.673835125448, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24649807, Length=189, Percent_Identity=30.6878306878307, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24657891, Length=278, Percent_Identity=27.3381294964029, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644244, Length=318, Percent_Identity=23.5849056603774, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360801, Length=176, Percent_Identity=27.8409090909091, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641720, Length=179, Percent_Identity=27.9329608938547, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360799, Length=179, Percent_Identity=27.9329608938547, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34058; Mature: 33927

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPLIYHEDYSPDFPADHRFPMDKFRLLRDYLIDSGLTSDVQLMRPELCPADILALAHD
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHCCC
PSYISRYLSGDLSREDQRRLGLPWSEALARRTIRAVGGSLLTAEQALKHGLACHLAGGTH
HHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCC
HAHYDYPAGFCIFNDLAVISQYLLQSGRVDKVLIFDCDVHQGDGTARILADTEDAITVSL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEEE
HCEKNFPARKAQSDWDIPLPMGMGDADYLNVVDDLLNYLLPLYKPDLVLYDAGVDVHKDD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCC
ALGYLQLTDQGLANRDEAVLRHCLSRDIPVMGVIGGGYSKDRLALARRHGILHHSAQRVW
CCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NDMGL
HHCCC
>Mature Secondary Structure 
SLPLIYHEDYSPDFPADHRFPMDKFRLLRDYLIDSGLTSDVQLMRPELCPADILALAHD
CCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHCCC
PSYISRYLSGDLSREDQRRLGLPWSEALARRTIRAVGGSLLTAEQALKHGLACHLAGGTH
HHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCC
HAHYDYPAGFCIFNDLAVISQYLLQSGRVDKVLIFDCDVHQGDGTARILADTEDAITVSL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEEE
HCEKNFPARKAQSDWDIPLPMGMGDADYLNVVDDLLNYLLPLYKPDLVLYDAGVDVHKDD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCC
ALGYLQLTDQGLANRDEAVLRHCLSRDIPVMGVIGGGYSKDRLALARRHGILHHSAQRVW
CCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NDMGL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]