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The map label for this gene is tesB [H]

Identifier: 66047520

GI number: 66047520

Start: 5119626

End: 5120495

Strand: Reverse

Name: tesB [H]

Synonym: Psyr_4293

Alternate gene names: 66047520

Gene position: 5120495-5119626 (Counterclockwise)

Preceding gene: 66047521

Following gene: 66047519

Centisome position: 84.03

GC content: 61.38

Gene sequence:

>870_bases
ATGAGCCAAGTGCTGGATGATCTGGTTGAGTTGCTGACGCTGGAAGCCATTGAAGAAAACCTGTTCCGCGGTCATAGCCA
GGACCTGGGCTTTCGCCAGTTGTTTGGTGGTCAGGTGCTGGGTCAGTCGCTGTCTGCCGCCAGTCAGACAGTTGAAGAGG
ACCGTCATGTTCACTCGCTGCACGGCTACTTTCTGCGTCCCGGCGATGCCGGTTTGCCGGTGGTCTATCAGGTGGACCGT
GTGCGTGACGGTGGCAGCTTCAGCACGCGCCGTGTCACTGCCATTCAGAAGGGCAAGCCGATCTTCACCTGCAGCGCTTC
GTTTCAGTACGACGAAGAGGGCTTCGAGCACCAGGCGACGATGCCGCAGATTGTCGGCCCGGAAGACCTGCCGTCCGAGC
TGGAGTTGCTGACCCGCCGCGCGCACCTGATTCCTGAAGCGATGCACGACAAGTTTCTGCGCTCCAAGCCGATCCAGTTC
CGCCCGGTGACCGCTGAAGATCCGTACGATCCCAAGCCCGGCGATCCCGTCAAATACGTGTGGTTCCGCGCCGATGGCAG
CCTCCCGGACGTGCAGGCGCTGCATCGTTACATGCTCGCCTATGCCTCCGACTTCAACTTGCTGACCACATCCCTGCTGC
CGCACGGCAAGACGGTCTGGCAGCGCGACATGCAGGTCGCCAGCCTTGACCATTCGCTGTGGTTCCACAACGACCTGCGT
GCCGATGACTGGCTGCTCTACGCGATGGACAGCCCCTGGGCAGGCAACTCGCGCGGCTTCTCGCGCGGCAGTATCTTCAA
CCGCACCGGGCAACTGGTCGCATCGGTCAGTCAGGAAGGGCTGATCCGCCATCGTAAGGATTGGGCATGA

Upstream 100 bases:

>100_bases
GTATCATTCCATTCCAGCGGGACGGGCCCGAGGCCTGTGGGAAAATGCAGCGACTGCTGTTGCCGTACAAGTGCAAAGTC
GATGTACGAGAGGAATGAGA

Downstream 100 bases:

>100_bases
CACTCGAAGGTATACGGCACTGGGTGTTCGACATGGACGGTACCTTGACCGTCCCTATCCACGACTTCCCGGCCATCAAA
CGTGAATTGGGCATCCCCCA

Product: Acyl-CoA thioesterase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSQVLDDLVELLTLEAIEENLFRGHSQDLGFRQLFGGQVLGQSLSAASQTVEEDRHVHSLHGYFLRPGDAGLPVVYQVDR
VRDGGSFSTRRVTAIQKGKPIFTCSASFQYDEEGFEHQATMPQIVGPEDLPSELELLTRRAHLIPEAMHDKFLRSKPIQF
RPVTAEDPYDPKPGDPVKYVWFRADGSLPDVQALHRYMLAYASDFNLLTTSLLPHGKTVWQRDMQVASLDHSLWFHNDLR
ADDWLLYAMDSPWAGNSRGFSRGSIFNRTGQLVASVSQEGLIRHRKDWA

Sequences:

>Translated_289_residues
MSQVLDDLVELLTLEAIEENLFRGHSQDLGFRQLFGGQVLGQSLSAASQTVEEDRHVHSLHGYFLRPGDAGLPVVYQVDR
VRDGGSFSTRRVTAIQKGKPIFTCSASFQYDEEGFEHQATMPQIVGPEDLPSELELLTRRAHLIPEAMHDKFLRSKPIQF
RPVTAEDPYDPKPGDPVKYVWFRADGSLPDVQALHRYMLAYASDFNLLTTSLLPHGKTVWQRDMQVASLDHSLWFHNDLR
ADDWLLYAMDSPWAGNSRGFSRGSIFNRTGQLVASVSQEGLIRHRKDWA
>Mature_288_residues
SQVLDDLVELLTLEAIEENLFRGHSQDLGFRQLFGGQVLGQSLSAASQTVEEDRHVHSLHGYFLRPGDAGLPVVYQVDRV
RDGGSFSTRRVTAIQKGKPIFTCSASFQYDEEGFEHQATMPQIVGPEDLPSELELLTRRAHLIPEAMHDKFLRSKPIQFR
PVTAEDPYDPKPGDPVKYVWFRADGSLPDVQALHRYMLAYASDFNLLTTSLLPHGKTVWQRDMQVASLDHSLWFHNDLRA
DDWLLYAMDSPWAGNSRGFSRGSIFNRTGQLVASVSQEGLIRHRKDWA

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=285, Percent_Identity=42.4561403508772, Blast_Score=222, Evalue=2e-58,
Organism=Escherichia coli, GI1786657, Length=284, Percent_Identity=51.7605633802817, Blast_Score=300, Evalue=6e-83,
Organism=Caenorhabditis elegans, GI71988741, Length=297, Percent_Identity=37.7104377104377, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17558508, Length=304, Percent_Identity=38.1578947368421, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17531889, Length=272, Percent_Identity=36.3970588235294, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI115532456, Length=272, Percent_Identity=36.3970588235294, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17531885, Length=272, Percent_Identity=36.3970588235294, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71982224, Length=300, Percent_Identity=31, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI212645202, Length=264, Percent_Identity=31.0606060606061, Blast_Score=118, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6322480, Length=336, Percent_Identity=25.5952380952381, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32735; Mature: 32604

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVLDDLVELLTLEAIEENLFRGHSQDLGFRQLFGGQVLGQSLSAASQTVEEDRHVHSL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
HGYFLRPGDAGLPVVYQVDRVRDGGSFSTRRVTAIQKGKPIFTCSASFQYDEEGFEHQAT
CCEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCC
MPQIVGPEDLPSELELLTRRAHLIPEAMHDKFLRSKPIQFRPVTAEDPYDPKPGDPVKYV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEE
WFRADGSLPDVQALHRYMLAYASDFNLLTTSLLPHGKTVWQRDMQVASLDHSLWFHNDLR
EEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHEECCCCC
ADDWLLYAMDSPWAGNSRGFSRGSIFNRTGQLVASVSQEGLIRHRKDWA
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQVLDDLVELLTLEAIEENLFRGHSQDLGFRQLFGGQVLGQSLSAASQTVEEDRHVHSL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
HGYFLRPGDAGLPVVYQVDRVRDGGSFSTRRVTAIQKGKPIFTCSASFQYDEEGFEHQAT
CCEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCC
MPQIVGPEDLPSELELLTRRAHLIPEAMHDKFLRSKPIQFRPVTAEDPYDPKPGDPVKYV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEE
WFRADGSLPDVQALHRYMLAYASDFNLLTTSLLPHGKTVWQRDMQVASLDHSLWFHNDLR
EEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHEECCCCC
ADDWLLYAMDSPWAGNSRGFSRGSIFNRTGQLVASVSQEGLIRHRKDWA
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]