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The map label for this gene is regB [H]

Identifier: 66047458

GI number: 66047458

Start: 5038879

End: 5040138

Strand: Reverse

Name: regB [H]

Synonym: Psyr_4231

Alternate gene names: 66047458

Gene position: 5040138-5038879 (Counterclockwise)

Preceding gene: 66047470

Following gene: 66047457

Centisome position: 82.71

GC content: 61.67

Gene sequence:

>1260_bases
ATGCTCGCCCCCGTTAAAATGCTTTCAGCCACACGACAAAACCTGTGGCGCCTGACATTCATCCGTATTCTGGTGCTGGC
CGCGCAGGCCGGCTCGGTCGGTATGGCCTGGCTGTTCGACTTTCTGCCGTTGCCCTGGCTGCAACTGTCGATCACCCTGG
GCTGCTCACTGGTGCTCTGCGGGCTGACGGTCATCCGTCTGCGCACCTCGCTGCCGCTCACCGAGCTTGAATATGCGCTG
CAACTGGCGCTGGACCTGCTGATCCACAGCGCGCTGCTGTATTACTCGGGCGGCTCGGCCAACCCGTTCGTTTCCTATTA
TCTGGTGCCGCTGACTATCGCCGCTGCCACGCTGCCGTGGCGCTACTCGCTGATCCTGTCCGGCTTTGCGCTGAGCATGT
ACACCTTGTTGATGGTGCGTTCCTACCCGCTGGAAACCGACTCCATCGCCCGGGAAAACATGCAGATCTACGGCATGTGG
CTGAGTTTTGCCCTGGCGGCGGCAGTAATCACCTTCTTTGCCGCGAAGATGGCCGAAGAGTTGCGTCGTCAGGAGCAACT
GCGTGCCGAGCGTCGCGAAGAAGGCCTGCGTGATCAGCAGTTGCTCGCCGTCGCGACCCAGGCCGCAGGGGCTGCCCATG
AATTGGGAACGCCGCTGGCAACCATGAGCGTGCTGCTCAAGGAGATGCGCCAGGATCACAGTGACCCGGCCTTGCAGGAT
GACCTGTCCGTGCTGCAGGAGCAGGTCAAGCAGTGCAAGCAGACCCTGCAGCAACTGGTGCGCGCCGCCGAAGCCAATCG
GCGTATGGCTGTCGAATATCAGGCTGCCACCCGCTGGCTGGATGAGTCCCTTAACCGCTGGCATCTGATGCGCCCGGAAG
TGAGTTACCGTTTCTATAAGCTGGGCAAGGGCGAAGCGCCGATGCTGGCGCCGCCGCCGGACCTGACTCAGGCGCTGCTC
AACCTGCTCAACAACGCTGCCGATGCCTGCCCCGATGGCCTTGAAGTCAACCTGGACTGGGACAGTGCGGAAATCTGCAT
CAGCATTCGCGACCATGGCGCGGGTGTGCCGCTGGCGATTGCCGAACAGATCGGCAAACCGTTCTTTACTACCAAGGGCA
AAGGTTTCGGCCTGGGTCTGTTCCTGAGCAAGGCCAGCGTCACCCGTGCGGGTGGCTCGGTGAAGCTCTACAGTCATGAA
GAAGGCGGTACGCTCACCGAGCTGCGCCTGCCCCGAGATACGCGAGGAGAAGAAGCATGA

Upstream 100 bases:

>100_bases
GAGTGCCCTGGCGTGCGGTGCGTTGACGCACTTTTTCAGTTTTGCCTCCCGCTTGGTTATACTCGCTGCGATCCGCCTGG
AGCACTCATCAGGAGAGCTC

Downstream 100 bases:

>100_bases
GTGACGATGACATCCAGGTCGAAGGCGAAGAGCTGCCGCACCTGCTGCTGGTAGATGACGACGCGACGTTCACCCGTGTG
ATGGCGAGGGCCATGAGCCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MLAPVKMLSATRQNLWRLTFIRILVLAAQAGSVGMAWLFDFLPLPWLQLSITLGCSLVLCGLTVIRLRTSLPLTELEYAL
QLALDLLIHSALLYYSGGSANPFVSYYLVPLTIAAATLPWRYSLILSGFALSMYTLLMVRSYPLETDSIARENMQIYGMW
LSFALAAAVITFFAAKMAEELRRQEQLRAERREEGLRDQQLLAVATQAAGAAHELGTPLATMSVLLKEMRQDHSDPALQD
DLSVLQEQVKQCKQTLQQLVRAAEANRRMAVEYQAATRWLDESLNRWHLMRPEVSYRFYKLGKGEAPMLAPPPDLTQALL
NLLNNAADACPDGLEVNLDWDSAEICISIRDHGAGVPLAIAEQIGKPFFTTKGKGFGLGLFLSKASVTRAGGSVKLYSHE
EGGTLTELRLPRDTRGEEA

Sequences:

>Translated_419_residues
MLAPVKMLSATRQNLWRLTFIRILVLAAQAGSVGMAWLFDFLPLPWLQLSITLGCSLVLCGLTVIRLRTSLPLTELEYAL
QLALDLLIHSALLYYSGGSANPFVSYYLVPLTIAAATLPWRYSLILSGFALSMYTLLMVRSYPLETDSIARENMQIYGMW
LSFALAAAVITFFAAKMAEELRRQEQLRAERREEGLRDQQLLAVATQAAGAAHELGTPLATMSVLLKEMRQDHSDPALQD
DLSVLQEQVKQCKQTLQQLVRAAEANRRMAVEYQAATRWLDESLNRWHLMRPEVSYRFYKLGKGEAPMLAPPPDLTQALL
NLLNNAADACPDGLEVNLDWDSAEICISIRDHGAGVPLAIAEQIGKPFFTTKGKGFGLGLFLSKASVTRAGGSVKLYSHE
EGGTLTELRLPRDTRGEEA
>Mature_419_residues
MLAPVKMLSATRQNLWRLTFIRILVLAAQAGSVGMAWLFDFLPLPWLQLSITLGCSLVLCGLTVIRLRTSLPLTELEYAL
QLALDLLIHSALLYYSGGSANPFVSYYLVPLTIAAATLPWRYSLILSGFALSMYTLLMVRSYPLETDSIARENMQIYGMW
LSFALAAAVITFFAAKMAEELRRQEQLRAERREEGLRDQQLLAVATQAAGAAHELGTPLATMSVLLKEMRQDHSDPALQD
DLSVLQEQVKQCKQTLQQLVRAAEANRRMAVEYQAATRWLDESLNRWHLMRPEVSYRFYKLGKGEAPMLAPPPDLTQALL
NLLNNAADACPDGLEVNLDWDSAEICISIRDHGAGVPLAIAEQIGKPFFTTKGKGFGLGLFLSKASVTRAGGSVKLYSHE
EGGTLTELRLPRDTRGEEA

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=28.6919831223629, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=273, Percent_Identity=27.8388278388278, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46445; Mature: 46445

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCEECCCCCCEEEHEEEHHHHEECCCEEEEEEECCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure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HHHHCCCCEECCCCCCEEEHEEEHHHHEECCCEEEEEEECCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]