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The map label for this gene is regA [H]

Identifier: 66047457

GI number: 66047457

Start: 5038319

End: 5038882

Strand: Reverse

Name: regA [H]

Synonym: Psyr_4230

Alternate gene names: 66047457

Gene position: 5038882-5038319 (Counterclockwise)

Preceding gene: 66047458

Following gene: 66047456

Centisome position: 82.69

GC content: 62.94

Gene sequence:

>564_bases
ATGAGTGACGATGACATCCAGGTCGAAGGCGAAGAGCTGCCGCACCTGCTGCTGGTAGATGACGACGCGACGTTCACCCG
TGTGATGGCGAGGGCCATGAGCCGTCGTGGTTTTCGCGTGAGCACCGCCGGCTCGGCTGAAGAAGGGCTGGCCCTGGCGC
AACAGGACATCCCCGAGTACGCCGCGCTGGACCTGAAGATGGACGGCGACTCCGGTCTGGTGCTGCTGCCCAAGCTGCTG
GAAATGGACCCGGAGATGCGCGTGGTGATTCTCACCGGTTATTCGAGCATTGCCACGGCGGTCGAAGCGATCAAGCGTGG
CGCGTGCAACTACCTGTGCAAACCGGCTGACGCTGATGACGTACTGGCAGCGCTGTTGTCCGAGCACGCCAACCTCGACA
CGCTGGTCCCGGAGAATCCGATGTCGGTGGACCGCTTGCAGTGGGAGCATATCCAGCGCGTGCTGACCGAGCACGAGGGC
AATATTTCAGCGACTGCGCGTGCGCTGGGCATGCATCGCCGGACCTTGCAGCGCAAGTTGCAGAAACGCCCCGTGCGACG
TTGA

Upstream 100 bases:

>100_bases
GCGTCACCCGTGCGGGTGGCTCGGTGAAGCTCTACAGTCATGAAGAAGGCGGTACGCTCACCGAGCTGCGCCTGCCCCGA
GATACGCGAGGAGAAGAAGC

Downstream 100 bases:

>100_bases
TGAAGGTTTTTTCATAGTGATCGATTAGGCGTTTTTTTGCTTCATTGTGCTCAGGCATCGTACGTTCAAAGAGAGCGAGC
CTGAACCACATGAATCGCAA

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSDDDIQVEGEELPHLLLVDDDATFTRVMARAMSRRGFRVSTAGSAEEGLALAQQDIPEYAALDLKMDGDSGLVLLPKLL
EMDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDVLAALLSEHANLDTLVPENPMSVDRLQWEHIQRVLTEHEG
NISATARALGMHRRTLQRKLQKRPVRR

Sequences:

>Translated_187_residues
MSDDDIQVEGEELPHLLLVDDDATFTRVMARAMSRRGFRVSTAGSAEEGLALAQQDIPEYAALDLKMDGDSGLVLLPKLL
EMDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDVLAALLSEHANLDTLVPENPMSVDRLQWEHIQRVLTEHEG
NISATARALGMHRRTLQRKLQKRPVRR
>Mature_186_residues
SDDDIQVEGEELPHLLLVDDDATFTRVMARAMSRRGFRVSTAGSAEEGLALAQQDIPEYAALDLKMDGDSGLVLLPKLLE
MDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADDVLAALLSEHANLDTLVPENPMSVDRLQWEHIQRVLTEHEGN
ISATARALGMHRRTLQRKLQKRPVRR

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=32, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788905, Length=111, Percent_Identity=36.036036036036, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=29.2452830188679, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR002197
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20731; Mature: 20600

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDDIQVEGEELPHLLLVDDDATFTRVMARAMSRRGFRVSTAGSAEEGLALAQQDIPEY
CCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCH
AALDLKMDGDSGLVLLPKLLEMDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADD
HEEEEEECCCCCEEECCHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCHHHCCCCCCHHH
VLAALLSEHANLDTLVPENPMSVDRLQWEHIQRVLTEHEGNISATARALGMHRRTLQRKL
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QKRPVRR
HHCCCCC
>Mature Secondary Structure 
SDDDIQVEGEELPHLLLVDDDATFTRVMARAMSRRGFRVSTAGSAEEGLALAQQDIPEY
CCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCH
AALDLKMDGDSGLVLLPKLLEMDPEMRVVILTGYSSIATAVEAIKRGACNYLCKPADADD
HEEEEEECCCCCEEECCHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCHHHCCCCCCHHH
VLAALLSEHANLDTLVPENPMSVDRLQWEHIQRVLTEHEGNISATARALGMHRRTLQRKL
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QKRPVRR
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA