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The map label for this gene is groES [H]

Identifier: 66047300

GI number: 66047300

Start: 4857219

End: 4857512

Strand: Reverse

Name: groES [H]

Synonym: Psyr_4073

Alternate gene names: 66047300

Gene position: 4857512-4857219 (Counterclockwise)

Preceding gene: 66047301

Following gene: 66047299

Centisome position: 79.71

GC content: 57.14

Gene sequence:

>294_bases
ATGAAGCTTCGTCCTCTGCATGACCGCGTCGTCATCCGTCGCAGTGAAGAAGAAACGAAAACTGCCGGCGGTATCGTTCT
GCCAGGTTCGGCTGCTGAAAAGCCTAACCGCGGCGAGATCGTTGCTGTGGGTACCGGCCGCGTGCTGGACAACGGCGAAG
TACGTGCGCTGGCTGTGAAAGTGGGTGACAAGGTTGTGTTCGGCCCTTATTCCGGCAGCAACACAGTGAAAGTAGACGGC
GAAGACCTGCTGGTGATGAGCGAGAACGAGATTCTTGCTGTCGTCGAAGGCTGA

Upstream 100 bases:

>100_bases
ATTCTGCGGTTCGCGCGTCGAACCGTAACCGGCAAGTCCGGATTTAAACCGGCCGGTGCACTCACCGGACGATCAAACAA
ACATAATCAGGAGATCGACA

Downstream 100 bases:

>100_bases
GTGCTCCCGCTGACTTCCGTTACTACTAAGTATTCAAGGAATAATGATCATGGCTGCTAAAGAAGTTAAATTCGGCGATT
CTGGCCGCAAAAAAATGCTC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MKLRPLHDRVVIRRSEEETKTAGGIVLPGSAAEKPNRGEIVAVGTGRVLDNGEVRALAVKVGDKVVFGPYSGSNTVKVDG
EDLLVMSENEILAVVEG

Sequences:

>Translated_97_residues
MKLRPLHDRVVIRRSEEETKTAGGIVLPGSAAEKPNRGEIVAVGTGRVLDNGEVRALAVKVGDKVVFGPYSGSNTVKVDG
EDLLVMSENEILAVVEG
>Mature_97_residues
MKLRPLHDRVVIRRSEEETKTAGGIVLPGSAAEKPNRGEIVAVGTGRVLDNGEVRALAVKVGDKVVFGPYSGSNTVKVDG
EDLLVMSENEILAVVEG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=41.7582417582418, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1790585, Length=97, Percent_Identity=59.7938144329897, Blast_Score=119, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=37.2340425531915, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324594, Length=90, Percent_Identity=42.2222222222222, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10268; Mature: 10268

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPLHDRVVIRRSEEETKTAGGIVLPGSAAEKPNRGEIVAVGTGRVLDNGEVRALAVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEECCEEECCCCEEEEEEE
VGDKVVFGPYSGSNTVKVDGEDLLVMSENEILAVVEG
ECCEEEECCCCCCCEEEECCCEEEEECCCCEEEEEEC
>Mature Secondary Structure
MKLRPLHDRVVIRRSEEETKTAGGIVLPGSAAEKPNRGEIVAVGTGRVLDNGEVRALAVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEECCEEECCCCEEEEEEE
VGDKVVFGPYSGSNTVKVDGEDLLVMSENEILAVVEG
ECCEEEECCCCCCCEEEECCCEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7845355 [H]