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The map label for this gene is yiaY [H]

Identifier: 66047214

GI number: 66047214

Start: 4744868

End: 4746016

Strand: Reverse

Name: yiaY [H]

Synonym: Psyr_3987

Alternate gene names: 66047214

Gene position: 4746016-4744868 (Counterclockwise)

Preceding gene: 66047215

Following gene: 66047213

Centisome position: 77.88

GC content: 59.53

Gene sequence:

>1149_bases
ATGATCAGCACTTTTTTCATCCCCGCTGTGAACATCATCGGCACTGGCTGCATTGACGAAGCCATGCTCGCCATACGCAA
ATACGGATTTCGCAAGGCCCTGATCGTCACGGATGCTGGCCTTGCCAGGGCCGGAGTAGCCAGTCAGGTCGCCGGGCTGT
TGGTGGAGCAGGGCATTGACTCGGTTGTGTACGACGGTGCCCGGCCCAACCCGACCATCGCCAACGTCGAGAACGGCCTG
GCCCTGTTGCAGGAGCGCCAGTGCGATTTCGTCATATCGCTGGGCGGTGGCTCGCCTCACGACTGTGCAAAAGGTATTGC
CCTGTGCGCCAGCAACGGGGGGCATATCAGCGATTATGAGGGCGTCGACCGTTCGGCAAAACCGCAGTTGCCATTGATTG
CCATCAATACCACCGCCGGAACCGCGAGTGAAATGACCCGCTTCTGCATCATTACCGACGAAGCCCGGCACGTAAAAATG
GCGATCATCGACCGCAACGTCACGCCGCTGCTGTCCGTGAATGATCCCGACATGATGGTCGCCATGCCCAGGTCGCTGAC
TGCCGCCACTGGCATGGATGCCTTGACTCACGCAATCGAAGCCTATGTCTCCACGGCTGCCAACCCGATCACTGACGCCT
GTGCGTTACAGGCTATGGCGCTGATCGCCAACAATTTGCGCGACGCATTCAACAACGGGGCCAATATCACTGCCCGCGAG
AACATGGCGTATGCCCAGTTTCTGGCTGGCATGGCGTTCAATAACGCGTCACTGGGCTACGTGCACGCCATGGCGCACCA
GTTGGGCGGCTTTTATGATTTGCCCCACGGTGTGTGCAACGCCGTATTGCTGCCCCATGTGCAGCGCTTCAACGCCAGCG
TCAGCGCTGCACGCCTGACCGACGTTGCACACGCCATGGGCAGCAATATCCGTGGGCTCTCTCCGGAAGAAGGCGCTCAG
GCAGCCATCGACGCGATTCGTGCATTGTCGGCTGCCGTGGAAATCCCGGCAGGTCTTGCTACGCTGGGCGTCAAGGAGGA
AGACTTCCCGATGCTGGCCAGCAATGCCCTGAAAGATGCCTGCGGCCTGACCAACCCGCGTCCTGCCGATCTTGAGCAGA
TTCAGGATATATTTCGCCAGGCGCTTTAA

Upstream 100 bases:

>100_bases
CGTTTGACTGCTTCGTTGCGCTGGATCAATGGTTGTACCTCGCGCAAGGCGGATGCTTGGCTCATCACCCCAGCATCCGC
GCTACCCTCGAGGGTCCGTC

Downstream 100 bases:

>100_bases
TCACCCCTGTAAAACAGGCCTGTCATGGACATGCTGCGGCCGTACACCCTTGCAGATCGTGAGCGATGTCTGGATATCTT
CGACACCAACGTCCCGCGCT

Product: Iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MISTFFIPAVNIIGTGCIDEAMLAIRKYGFRKALIVTDAGLARAGVASQVAGLLVEQGIDSVVYDGARPNPTIANVENGL
ALLQERQCDFVISLGGGSPHDCAKGIALCASNGGHISDYEGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARHVKM
AIIDRNVTPLLSVNDPDMMVAMPRSLTAATGMDALTHAIEAYVSTAANPITDACALQAMALIANNLRDAFNNGANITARE
NMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQRFNASVSAARLTDVAHAMGSNIRGLSPEEGAQ
AAIDAIRALSAAVEIPAGLATLGVKEEDFPMLASNALKDACGLTNPRPADLEQIQDIFRQAL

Sequences:

>Translated_382_residues
MISTFFIPAVNIIGTGCIDEAMLAIRKYGFRKALIVTDAGLARAGVASQVAGLLVEQGIDSVVYDGARPNPTIANVENGL
ALLQERQCDFVISLGGGSPHDCAKGIALCASNGGHISDYEGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARHVKM
AIIDRNVTPLLSVNDPDMMVAMPRSLTAATGMDALTHAIEAYVSTAANPITDACALQAMALIANNLRDAFNNGANITARE
NMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQRFNASVSAARLTDVAHAMGSNIRGLSPEEGAQ
AAIDAIRALSAAVEIPAGLATLGVKEEDFPMLASNALKDACGLTNPRPADLEQIQDIFRQAL
>Mature_382_residues
MISTFFIPAVNIIGTGCIDEAMLAIRKYGFRKALIVTDAGLARAGVASQVAGLLVEQGIDSVVYDGARPNPTIANVENGL
ALLQERQCDFVISLGGGSPHDCAKGIALCASNGGHISDYEGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARHVKM
AIIDRNVTPLLSVNDPDMMVAMPRSLTAATGMDALTHAIEAYVSTAANPITDACALQAMALIANNLRDAFNNGANITARE
NMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQRFNASVSAARLTDVAHAMGSNIRGLSPEEGAQ
AAIDAIRALSAAVEIPAGLATLGVKEEDFPMLASNALKDACGLTNPRPADLEQIQDIFRQAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=408, Percent_Identity=26.4705882352941, Blast_Score=131, Evalue=9e-31,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=70, Blast_Score=537, Evalue=1e-154,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=43.010752688172, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI87082107, Length=380, Percent_Identity=35.7894736842105, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1787493, Length=383, Percent_Identity=34.2036553524804, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1789386, Length=329, Percent_Identity=26.1398176291793, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17537053, Length=412, Percent_Identity=26.9417475728155, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321181, Length=382, Percent_Identity=53.9267015706806, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=26.3414634146341, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40072; Mature: 40072

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTFFIPAVNIIGTGCIDEAMLAIRKYGFRKALIVTDAGLARAGVASQVAGLLVEQGID
CCCEEEEHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCH
SVVYDGARPNPTIANVENGLALLQERQCDFVISLGGGSPHDCAKGIALCASNGGHISDYE
HHHCCCCCCCCCHHCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHEEECCCCCCCCCC
GVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARHVKMAIIDRNVTPLLSVNDPDMMV
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCEEEECCCCCEEE
AMPRSLTAATGMDALTHAIEAYVSTAANPITDACALQAMALIANNLRDAFNNGANITARE
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
NMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQRFNASVSAARLT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
DVAHAMGSNIRGLSPEEGAQAAIDAIRALSAAVEIPAGLATLGVKEEDFPMLASNALKDA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHH
CGLTNPRPADLEQIQDIFRQAL
HCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MISTFFIPAVNIIGTGCIDEAMLAIRKYGFRKALIVTDAGLARAGVASQVAGLLVEQGID
CCCEEEEHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCH
SVVYDGARPNPTIANVENGLALLQERQCDFVISLGGGSPHDCAKGIALCASNGGHISDYE
HHHCCCCCCCCCHHCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHEEECCCCCCCCCC
GVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARHVKMAIIDRNVTPLLSVNDPDMMV
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCEEEECCCCCEEE
AMPRSLTAATGMDALTHAIEAYVSTAANPITDACALQAMALIANNLRDAFNNGANITARE
ECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
NMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQRFNASVSAARLT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
DVAHAMGSNIRGLSPEEGAQAAIDAIRALSAAVEIPAGLATLGVKEEDFPMLASNALKDA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHH
CGLTNPRPADLEQIQDIFRQAL
HCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]