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The map label for this gene is rnc [H]

Identifier: 66047178

GI number: 66047178

Start: 4698686

End: 4699375

Strand: Reverse

Name: rnc [H]

Synonym: Psyr_3951

Alternate gene names: 66047178

Gene position: 4699375-4698686 (Counterclockwise)

Preceding gene: 66047179

Following gene: 66047177

Centisome position: 77.12

GC content: 61.16

Gene sequence:

>690_bases
GTGAGCGTATCCTTGAGCCGCCTTGAGCGTCAGCTCGGCTACACCTTCAAGGATCAGGAGCTGATGGTCCTGGCCCTGAC
CCATCGCAGTTTTGCCGGTCGCAACAATGAGCGTCTGGAGTTTCTCGGTGATGCCATTCTCAACTTCGTGGCCGGCGAGG
CGCTGTTCGAGCGCTTCCCCCAGGCTCGCGAAGGCCAGTTGTCCCGCTTGCGCGCGCGGCTGGTGAAGGGCGAAACCCTG
GCGTTGCTGGCGCGTGGTTTTGATCTGGGCGAGTACTTGCGCCTTGGCTCGGGCGAGTTGAAAAGCGGTGGTTTCCGTCG
TGAGTCGATTCTCGCCGACGCGCTCGAGGCGCTGATCGGGGCGATCTATCTGGATGCAGGCATGGAAGCAGCGCGCGAGC
GCGTCCTGGCCTGGCTGACCACCGAATTTGACAGCCTGACGCTGGTGGACACCAACAAGGACCCCAAGACCCGACTGCAG
GAATTTCTCCAGTCGCGGGCCTGTGAACTGCCGCGTTACGAGGTGGTGGATATCCAGGGCGAACCGCATTGCCGGACGTT
TTTCGTCGAATGCGAGATCAACCTATTGAATGAAAAAAGCCGAGGACAGGGTGTCAGCCGCCGGATTGCCGAACAGGTAG
CCGCCGCAGCAGCACTCATCGCCCTGGGCGTGGAGAACGGTCATGAATGA

Upstream 100 bases:

>100_bases
ATGCGTTCCAGGCTCATTTGAACTATGAGCAGCGTGAACCGTGGTTCCAGAACATCGATCTGGTGTTGAAGTTCGACAAG
CAATTCAGCGTGGGTAAACC

Downstream 100 bases:

>100_bases
TACAACCGCAACACGCTGTGGCTATGTTGCCATTGTCGGCCGTCCCAACGTAGGCAAGTCCACGCTGCTCAACCACATTC
TCGGTCAGAAGCTCGCGATC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSVSLSRLERQLGYTFKDQELMVLALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFPQAREGQLSRLRARLVKGETL
ALLARGFDLGEYLRLGSGELKSGGFRRESILADALEALIGAIYLDAGMEAARERVLAWLTTEFDSLTLVDTNKDPKTRLQ
EFLQSRACELPRYEVVDIQGEPHCRTFFVECEINLLNEKSRGQGVSRRIAEQVAAAAALIALGVENGHE

Sequences:

>Translated_229_residues
MSVSLSRLERQLGYTFKDQELMVLALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFPQAREGQLSRLRARLVKGETL
ALLARGFDLGEYLRLGSGELKSGGFRRESILADALEALIGAIYLDAGMEAARERVLAWLTTEFDSLTLVDTNKDPKTRLQ
EFLQSRACELPRYEVVDIQGEPHCRTFFVECEINLLNEKSRGQGVSRRIAEQVAAAAALIALGVENGHE
>Mature_228_residues
SVSLSRLERQLGYTFKDQELMVLALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFPQAREGQLSRLRARLVKGETLA
LLARGFDLGEYLRLGSGELKSGGFRRESILADALEALIGAIYLDAGMEAARERVLAWLTTEFDSLTLVDTNKDPKTRLQE
FLQSRACELPRYEVVDIQGEPHCRTFFVECEINLLNEKSRGQGVSRRIAEQVAAAAALIALGVENGHE

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030234, Length=226, Percent_Identity=30.9734513274336, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI155030236, Length=226, Percent_Identity=30.9734513274336, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1788920, Length=207, Percent_Identity=55.0724637681159, Blast_Score=236, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI193202651, Length=191, Percent_Identity=28.7958115183246, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17506883, Length=191, Percent_Identity=28.7958115183246, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17137682, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 25575; Mature: 25443

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSLSRLERQLGYTFKDQELMVLALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFP
CCCCHHHHHHHHCCCCCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
QAREGQLSRLRARLVKGETLALLARGFDLGEYLRLGSGELKSGGFRRESILADALEALIG
CCCCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AIYLDAGMEAARERVLAWLTTEFDSLTLVDTNKDPKTRLQEFLQSRACELPRYEVVDIQG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECC
EPHCRTFFVECEINLLNEKSRGQGVSRRIAEQVAAAAALIALGVENGHE
CCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SVSLSRLERQLGYTFKDQELMVLALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFP
CCCHHHHHHHHCCCCCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
QAREGQLSRLRARLVKGETLALLARGFDLGEYLRLGSGELKSGGFRRESILADALEALIG
CCCCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AIYLDAGMEAARERVLAWLTTEFDSLTLVDTNKDPKTRLQEFLQSRACELPRYEVVDIQG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECC
EPHCRTFFVECEINLLNEKSRGQGVSRRIAEQVAAAAALIALGVENGHE
CCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA