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The map label for this gene is mmlH [H]

Identifier: 66047163

GI number: 66047163

Start: 4680987

End: 4682327

Strand: Reverse

Name: mmlH [H]

Synonym: Psyr_3936

Alternate gene names: 66047163

Gene position: 4682327-4680987 (Counterclockwise)

Preceding gene: 66047164

Following gene: 66047162

Centisome position: 76.84

GC content: 61.37

Gene sequence:

>1341_bases
ATGTCCATTTACAATAAGCTCGACCTGACCGGCTGGAAACCTGAGCAACTGACTCCGGAGCAAGTACGGTTCGCCACATG
GATTGCGTTTTTCGCGTGGGTGTTTGCGGTATATGACTTCATTCTGTTTGGCACGCTGTTACCGGAAATCGGTCGGCATT
TCAGCTGGAGTGAGGTCGAACAGGCCGAAATCGCGACCTGGGTCGCGGTCGGCACCGCGGTGGTGGCTTTGGCCATCGGC
CCGCTGGTAGATCGCCTGGGACGGCGCGTGGGTATCATTTTCACCGTGAGTGGCTCGGCGATCTGCTCGGCGCTCACGGC
CATCGGCGGAGCGTGGGGCAAGTCGCCCCTGATCCTCATTCGTTCGCTGGGCGGTCTGGGTTATGCAGAAGAAACGGTCA
ACGCGACCTATCTGAGCGAAATCTATGCTGCATCCGACGACCCGCGACTGACCAAGCGCCGTGGCTTCATCTACAGCCTG
GTGCAGGGCGGCTGGCCGGTCGGTGCGCTGATCGCGGCCGGTCTGACGGCGGTGCTGTTGCCGGTCATCGGCTGGCAGGG
TTGCTTCGTCTTTGCTGCGATCCCGGCCATCGTCATCGCGATCCTGGCGCGCAAGCTCAAGGAGAGTCCGCAGTTTCAGA
TCCATCAACGCATCACCCAATTGCGCAAGAAGGGCGACCTCAGCCAGGCGAAGGCCGTGGCGCAGACTTACGGGGTGGAT
TACGAAGAACACAGCAAGGCCGGTATCGGCGCTGCCTTTCGCGGTTCGTCGCGTCGCGCGACCCTGGTGATCGGTGCTGC
GATCCTGCTCAACTGGGCGGCCATTCAGGTGTTCAGTGTGCTGGGTACGACGGTGATCGTCAGCGTCCACCACATCTCGT
TCGAGAACTCGCTGATCATTCTGGTGCTGTCCAACCTGGTGGGCTATTGCGGCTACCTGTGTCACGGCTGGATGGGTGAC
CGGATCGGTCGCCGTAATGTCATCGGCCTCGGCTGGATGTTCGGCGGCCTGGCGTTTGCCGGCATGCTTTACGGGCCAAG
CAACATGGTGACGGTGGTCGGCTTGTACAGCCTGGGGCTGTTCTTCCTGATCGGCCCTTACTCGGCGGCATTGTTCTTCA
TCAGCGAAAGCTTCCCGACCAGCATTCGTGCCACGGGCGGCGCAATCATCCATGCCATGGGCCCGCTCGGTGCCGTGGTC
GCAGGCTTTGGTGCCACATCGGTACTGAGCGCCGGCGGCGACTGGCAGACCTCGGCGTTGTACTTCGGCGCAGTGCCTTG
CTTCCTGTCGGGTGCGCTGATGTTCGCGGCTAAACACGTGCGACCTGAAACGGTGAAATGA

Upstream 100 bases:

>100_bases
TGCTGGCGTCAAGTTCGTCACTTTCGACGAGATTGCCGACGACTTCGTGCGTCGCAACCCCCGTACCCGCTGATTCATTG
CCCTGTCCGAGGCGTCACTC

Downstream 100 bases:

>100_bases
GGAGCAGCACATGACGCGTAAAGTTGCAGTGATAACCGGTGCCGCCAGTGGCATTGGTCAGGCCCTGGTAGTGGCTTTTG
CCCGCCAGGGGGTGGCGGTG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSIYNKLDLTGWKPEQLTPEQVRFATWIAFFAWVFAVYDFILFGTLLPEIGRHFSWSEVEQAEIATWVAVGTAVVALAIG
PLVDRLGRRVGIIFTVSGSAICSALTAIGGAWGKSPLILIRSLGGLGYAEETVNATYLSEIYAASDDPRLTKRRGFIYSL
VQGGWPVGALIAAGLTAVLLPVIGWQGCFVFAAIPAIVIAILARKLKESPQFQIHQRITQLRKKGDLSQAKAVAQTYGVD
YEEHSKAGIGAAFRGSSRRATLVIGAAILLNWAAIQVFSVLGTTVIVSVHHISFENSLIILVLSNLVGYCGYLCHGWMGD
RIGRRNVIGLGWMFGGLAFAGMLYGPSNMVTVVGLYSLGLFFLIGPYSAALFFISESFPTSIRATGGAIIHAMGPLGAVV
AGFGATSVLSAGGDWQTSALYFGAVPCFLSGALMFAAKHVRPETVK

Sequences:

>Translated_446_residues
MSIYNKLDLTGWKPEQLTPEQVRFATWIAFFAWVFAVYDFILFGTLLPEIGRHFSWSEVEQAEIATWVAVGTAVVALAIG
PLVDRLGRRVGIIFTVSGSAICSALTAIGGAWGKSPLILIRSLGGLGYAEETVNATYLSEIYAASDDPRLTKRRGFIYSL
VQGGWPVGALIAAGLTAVLLPVIGWQGCFVFAAIPAIVIAILARKLKESPQFQIHQRITQLRKKGDLSQAKAVAQTYGVD
YEEHSKAGIGAAFRGSSRRATLVIGAAILLNWAAIQVFSVLGTTVIVSVHHISFENSLIILVLSNLVGYCGYLCHGWMGD
RIGRRNVIGLGWMFGGLAFAGMLYGPSNMVTVVGLYSLGLFFLIGPYSAALFFISESFPTSIRATGGAIIHAMGPLGAVV
AGFGATSVLSAGGDWQTSALYFGAVPCFLSGALMFAAKHVRPETVK
>Mature_445_residues
SIYNKLDLTGWKPEQLTPEQVRFATWIAFFAWVFAVYDFILFGTLLPEIGRHFSWSEVEQAEIATWVAVGTAVVALAIGP
LVDRLGRRVGIIFTVSGSAICSALTAIGGAWGKSPLILIRSLGGLGYAEETVNATYLSEIYAASDDPRLTKRRGFIYSLV
QGGWPVGALIAAGLTAVLLPVIGWQGCFVFAAIPAIVIAILARKLKESPQFQIHQRITQLRKKGDLSQAKAVAQTYGVDY
EEHSKAGIGAAFRGSSRRATLVIGAAILLNWAAIQVFSVLGTTVIVSVHHISFENSLIILVLSNLVGYCGYLCHGWMGDR
IGRRNVIGLGWMFGGLAFAGMLYGPSNMVTVVGLYSLGLFFLIGPYSAALFFISESFPTSIRATGGAIIHAMGPLGAVVA
GFGATSVLSAGGDWQTSALYFGAVPCFLSGALMFAAKHVRPETVK

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI32564663, Length=409, Percent_Identity=23.2273838630807, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47650; Mature: 47519

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SIYNKLDLTGWKPEQLTPEQVRFATWIAFFAWVFAVYDFILFGTLLPEIGRHFSWSEVE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QAEIATWVAVGTAVVALAIGPLVDRLGRRVGIIFTVSGSAICSALTAIGGAWGKSPLILI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCCCHHHHH
RSLGGLGYAEETVNATYLSEIYAASDDPRLTKRRGFIYSLVQGGWPVGALIAAGLTAVLL
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHH
PVIGWQGCFVFAAIPAIVIAILARKLKESPQFQIHQRITQLRKKGDLSQAKAVAQTYGVD
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
YEEHSKAGIGAAFRGSSRRATLVIGAAILLNWAAIQVFSVLGTTVIVSVHHISFENSLII
HHHCCCCCCCCEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHH
LVLSNLVGYCGYLCHGWMGDRIGRRNVIGLGWMFGGLAFAGMLYGPSNMVTVVGLYSLGL
HHHHHHHHHHHHHHHCHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FFLIGPYSAALFFISESFPTSIRATGGAIIHAMGPLGAVVAGFGATSVLSAGGDWQTSAL
HHHHHHHHHHHHEEECCCCCCCCCCCCEEEEECCHHHHHHHCCCHHHHHCCCCCCCCCHH
YFGAVPCFLSGALMFAAKHVRPETVK
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]