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The map label for this gene is gltK [H]

Identifier: 66047137

GI number: 66047137

Start: 4652944

End: 4653609

Strand: Direct

Name: gltK [H]

Synonym: Psyr_3910

Alternate gene names: 66047137

Gene position: 4652944-4653609 (Clockwise)

Preceding gene: 66047136

Following gene: 66047138

Centisome position: 76.36

GC content: 58.71

Gene sequence:

>666_bases
ATGGACTTCACTGGAATCGTTCCGGCCATTCCCGGTCTGTGGAACGGCATGGTCATGACCCTCAAGCTGATGGCGATGGG
TGTGGTCGGCGGCCTGGTGCTTGGCACGCTGCTGGCGTTGATGCGCCTGTCATCGAACAAGCTGCTGGCCAATGTGGCCG
GCGCCTACGTGAACTACTTTCGTTCGATCCCGCTGCTGCTGGTGATCACCTGGTTCTATCTGGCCGTGCCGTTCGTGCTG
CGCTGGATTACCGGTGAAGACACGCCCATCGGTGCGTTTGCCTCCTGCGTCGTGGCCTTCATGATGTTCGAAGCCGCGTA
CTTCTGCGAAATCGTCCGTGCCGGTGTGCAGTCGATCTCCAAGGGACAAATGGGCGCCGCTCAGGCGCTGGGCATGAACT
ACTCGCAGATGATGCGACTGATCATCCTGCCCCAGGCGTTTCGCAAGATGACCCCGCTGCTGCTGCAACAGAGCATCATT
CTGTTTCAGGACACCTCTCTGGTGTACACCGTCGGCCTCGTCGATTTTCTCAACGCATCGCGCTCCAGTGGCGACATCAT
CGGGCGCGCCAACGAGTTCCTGATCATTGCCGGTCTGGTGTATTTCACGATCAGCTTTGCCGCCTCGCTGCTGGTGAAGC
GTCTGCAAAAAAGGTTTGCCGTATGA

Upstream 100 bases:

>100_bases
GCTCATCTACTTCACGCTGAACATGAGCCTGATGCTGCTGATGCGTGCGATCGAGAAGAAAGTCGCCGTACCGGGACTCA
TCTCACTGGGGGGCAAATAA

Downstream 100 bases:

>100_bases
TTTCCATCAAAAACGTCAACAAGTGGTATGGGGACTTCCAGGTACTGACCGATTGCAGCACCGAGGTCAGCAAGGGCGAA
GTGGTGGTGGTGTGCGGCCC

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDFTGIVPAIPGLWNGMVMTLKLMAMGVVGGLVLGTLLALMRLSSNKLLANVAGAYVNYFRSIPLLLVITWFYLAVPFVL
RWITGEDTPIGAFASCVVAFMMFEAAYFCEIVRAGVQSISKGQMGAAQALGMNYSQMMRLIILPQAFRKMTPLLLQQSII
LFQDTSLVYTVGLVDFLNASRSSGDIIGRANEFLIIAGLVYFTISFAASLLVKRLQKRFAV

Sequences:

>Translated_221_residues
MDFTGIVPAIPGLWNGMVMTLKLMAMGVVGGLVLGTLLALMRLSSNKLLANVAGAYVNYFRSIPLLLVITWFYLAVPFVL
RWITGEDTPIGAFASCVVAFMMFEAAYFCEIVRAGVQSISKGQMGAAQALGMNYSQMMRLIILPQAFRKMTPLLLQQSII
LFQDTSLVYTVGLVDFLNASRSSGDIIGRANEFLIIAGLVYFTISFAASLLVKRLQKRFAV
>Mature_221_residues
MDFTGIVPAIPGLWNGMVMTLKLMAMGVVGGLVLGTLLALMRLSSNKLLANVAGAYVNYFRSIPLLLVITWFYLAVPFVL
RWITGEDTPIGAFASCVVAFMMFEAAYFCEIVRAGVQSISKGQMGAAQALGMNYSQMMRLIILPQAFRKMTPLLLQQSII
LFQDTSLVYTVGLVDFLNASRSSGDIIGRANEFLIIAGLVYFTISFAASLLVKRLQKRFAV

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=220, Percent_Identity=54.0909090909091, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI87082239, Length=209, Percent_Identity=33.4928229665072, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787030, Length=223, Percent_Identity=33.6322869955157, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786874, Length=212, Percent_Identity=30.188679245283, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788226, Length=217, Percent_Identity=33.6405529953917, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788645, Length=219, Percent_Identity=30.5936073059361, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=24.1706161137441, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787087, Length=217, Percent_Identity=23.5023041474654, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994930, Length=135, Percent_Identity=31.8518518518519, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24199; Mature: 24199

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTGIVPAIPGLWNGMVMTLKLMAMGVVGGLVLGTLLALMRLSSNKLLANVAGAYVNYF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RSIPLLLVITWFYLAVPFVLRWITGEDTPIGAFASCVVAFMMFEAAYFCEIVRAGVQSIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGQMGAAQALGMNYSQMMRLIILPQAFRKMTPLLLQQSIILFQDTSLVYTVGLVDFLNAS
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHCC
RSSGDIIGRANEFLIIAGLVYFTISFAASLLVKRLQKRFAV
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFTGIVPAIPGLWNGMVMTLKLMAMGVVGGLVLGTLLALMRLSSNKLLANVAGAYVNYF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RSIPLLLVITWFYLAVPFVLRWITGEDTPIGAFASCVVAFMMFEAAYFCEIVRAGVQSIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGQMGAAQALGMNYSQMMRLIILPQAFRKMTPLLLQQSIILFQDTSLVYTVGLVDFLNAS
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHCC
RSSGDIIGRANEFLIIAGLVYFTISFAASLLVKRLQKRFAV
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]