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The map label for this gene is bvgA [H]

Identifier: 66047117

GI number: 66047117

Start: 4630664

End: 4631290

Strand: Reverse

Name: bvgA [H]

Synonym: Psyr_3890

Alternate gene names: 66047117

Gene position: 4631290-4630664 (Counterclockwise)

Preceding gene: 66047119

Following gene: 66047112

Centisome position: 76.0

GC content: 56.62

Gene sequence:

>627_bases
ATGAATAAAGTGCTGATCGTGGATGATCATCCCGTCATTCGCCTTGCTGTACGCATGCTGATGGAGCGTCATGGCTATGA
GGTCATCGCGGAGACTGACAACGGTGTGGATGCGCTGCAACTGGCGCGTGAGCACCTCCCGGATATCGTCATTCTTGATA
TCGGTATCCCCAAGCTCGACGGGCTGGAGGTGATTGCCCGTCTGTCAGCCATGACGCTGCCATTCAAGGTGCTGATCCTG
ACCTCCCAGGCGCCAGGCCATTTCTCCATGCGCTGCATGCAGGCCGGGGCCGCCGGCTATGTCTGCAAACAGCAGGATCT
GACCGAGCTTCTCAGTGCCATCAAGGCGGTACTGTCAGGGTACAGCTACTTTCCCAACCAGGCATTGCACACCGTTCGCT
CCAGTATGGGCAACGCGAGTGAGTCGGACATGGTCGACCGACTTTCCGGCAGGGAGATGATGGTTCTGCAGCAGTTGGCT
CGAGGCAAGACCAACAAGGAAATTGCAGACGGCATGTTTCTGAGCAACAAGACCGTCAGCACCTATAAAACGCGTTTGTT
GCTCAAGCTCAACGCGCATTCGCTGGTCGATCTGATCGAGCTCGCCCAGCGTAACGGGCTTGTCTGA

Upstream 100 bases:

>100_bases
TTTGGCTGTCAGTCCACAAGGGTGAGCGCCATGCAAAGCAGTAAACGACTAAGTTATTGTGCTGGCTCTGAAAATTCGAA
TAGCGAAAAATGGACTGCCC

Downstream 100 bases:

>100_bases
GTAGGGATTGTCGAAAAGGGTTGTGGCTGATGCCTGGCCATGCAGGTCAGCCATTCAGTATTCATTTCCTGTATTGATCA
CGTATTGAAGCCTCTTCTGC

Product: LuxR response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNKVLIVDDHPVIRLAVRMLMERHGYEVIAETDNGVDALQLAREHLPDIVILDIGIPKLDGLEVIARLSAMTLPFKVLIL
TSQAPGHFSMRCMQAGAAGYVCKQQDLTELLSAIKAVLSGYSYFPNQALHTVRSSMGNASESDMVDRLSGREMMVLQQLA
RGKTNKEIADGMFLSNKTVSTYKTRLLLKLNAHSLVDLIELAQRNGLV

Sequences:

>Translated_208_residues
MNKVLIVDDHPVIRLAVRMLMERHGYEVIAETDNGVDALQLAREHLPDIVILDIGIPKLDGLEVIARLSAMTLPFKVLIL
TSQAPGHFSMRCMQAGAAGYVCKQQDLTELLSAIKAVLSGYSYFPNQALHTVRSSMGNASESDMVDRLSGREMMVLQQLA
RGKTNKEIADGMFLSNKTVSTYKTRLLLKLNAHSLVDLIELAQRNGLV
>Mature_208_residues
MNKVLIVDDHPVIRLAVRMLMERHGYEVIAETDNGVDALQLAREHLPDIVILDIGIPKLDGLEVIARLSAMTLPFKVLIL
TSQAPGHFSMRCMQAGAAGYVCKQQDLTELLSAIKAVLSGYSYFPNQALHTVRSSMGNASESDMVDRLSGREMMVLQQLA
RGKTNKEIADGMFLSNKTVSTYKTRLLLKLNAHSLVDLIELAQRNGLV

Specific function: Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=35.9223300970874, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=37.9310344827586, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=34.4497607655502, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=35.3846153846154, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=29.6116504854369, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1787375, Length=176, Percent_Identity=26.1363636363636, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788191, Length=105, Percent_Identity=37.1428571428571, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=27.3224043715847, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=30.9090909090909, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22960; Mature: 22960

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVLIVDDHPVIRLAVRMLMERHGYEVIAETDNGVDALQLAREHLPDIVILDIGIPKLD
CCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCC
GLEVIARLSAMTLPFKVLILTSQAPGHFSMRCMQAGAAGYVCKQQDLTELLSAIKAVLSG
HHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCC
YSYFPNQALHTVRSSMGNASESDMVDRLSGREMMVLQQLARGKTNKEIADGMFLSNKTVS
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCCEEECCCCHH
TYKTRLLLKLNAHSLVDLIELAQRNGLV
HHHEEEEEEECHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVLIVDDHPVIRLAVRMLMERHGYEVIAETDNGVDALQLAREHLPDIVILDIGIPKLD
CCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCC
GLEVIARLSAMTLPFKVLILTSQAPGHFSMRCMQAGAAGYVCKQQDLTELLSAIKAVLSG
HHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCC
YSYFPNQALHTVRSSMGNASESDMVDRLSGREMMVLQQLARGKTNKEIADGMFLSNKTVS
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCCEEECCCCHH
TYKTRLLLKLNAHSLVDLIELAQRNGLV
HHHEEEEEEECHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]