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The map label for this gene is tsx [H]

Identifier: 66047085

GI number: 66047085

Start: 4598394

End: 4599353

Strand: Direct

Name: tsx [H]

Synonym: Psyr_3858

Alternate gene names: 66047085

Gene position: 4598394-4599353 (Clockwise)

Preceding gene: 66047084

Following gene: 66047086

Centisome position: 75.46

GC content: 61.46

Gene sequence:

>960_bases
ATGCCACAGCCGCCATTCACCCGACCCGCAATGCCCTCAAGATTTCTCATGCCTCTGCTGTTCGCCGCCGCCGCGGCGCT
GCCCTGTACCAGCGTCCTGGCAGCGCCCGCCACCGCCGAAGACTCGGCGCAGGGCGAAGCACTCAGCCCGCCCGCCTCGC
CCAAGGAAGGTAAAGGCGCGTATTTTTCAGACTGGTTCAACCAGGACCTGACGCTGATCGGCAGCAAGGACATCAGCTTC
GGCCCCAAGCCCAACGATGACATCTACCTGGAGTACGAATACTTCGGCCGCAAAGGGCCGTTCGAGCTGTATGGCTATGT
CGACGTACCGAAGATCCTCGGCATCGGCAACGATAATGACAAAGGCGTCTGGGACCACGGCTCGCCGCTGTTCATGGAGC
ACGAGCCACGCATCTCGATCGACTACCTCGCCGGGCGCAGTCTGGCCGTCGGGCCGTTCAAGGAATGGTACGTCGCCTTC
GACTGGATCTATGACCACGGCAGCAATACGGCCAACCGGGCCAACACCCTGTACAGCGGCCTGGGCACTGACATCGATAC
CCACTCGCGGGTCAATCTGTCAGCCAACTTCTATGGCCGCTACCAGTGGGAGAACTACGGCGCCAGCAACGAGTACTCGT
GGGACGGCTACCGCGCGCAGCTCAAATACATCGTACCGATCAGCACCTTCGATAACGGTGCGTCGCTGACCTACATCGGC
TTCACCAACTTCGATTTCGGCTCGGACCTCAAGAACGATCCGGCACGCACCGGCAACTCCACGGTCGCCACCAATGTGCT
GCTTTATGCCTTCACGCACCTGCGCTTCACCCTGGTTGGCCGCTACTTCCACAACGGCGGCAACTGGCAGGACGGCAGCG
AGCTGAACTTCGGCGATGGCAACTTCCGCGCGCGCTCCGATGGCTGGGGCTATTACGCAGGCGTGGGTTACCAGTTCTGA

Upstream 100 bases:

>100_bases
CTGCACTTGATATCCAAGGCATTCAACATCTTGAAACAGTTTGGCATGGGCTGTGCAAACGCTTGCGATCAGCAGTACGC
GCCCACGAAAAGGAGCTTCA

Downstream 100 bases:

>100_bases
ACCTTATTATGACGACAGGAGTTTTCATGAAACACACCACTCGCAACACGCTCTGCGCCACGCTGGCACTGCTCAGCCCG
GCTGTCTGGGCGGCTACCGC

Product: nucleoside-specific channel-forming protein, Tsx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MPQPPFTRPAMPSRFLMPLLFAAAAALPCTSVLAAPATAEDSAQGEALSPPASPKEGKGAYFSDWFNQDLTLIGSKDISF
GPKPNDDIYLEYEYFGRKGPFELYGYVDVPKILGIGNDNDKGVWDHGSPLFMEHEPRISIDYLAGRSLAVGPFKEWYVAF
DWIYDHGSNTANRANTLYSGLGTDIDTHSRVNLSANFYGRYQWENYGASNEYSWDGYRAQLKYIVPISTFDNGASLTYIG
FTNFDFGSDLKNDPARTGNSTVATNVLLYAFTHLRFTLVGRYFHNGGNWQDGSELNFGDGNFRARSDGWGYYAGVGYQF

Sequences:

>Translated_319_residues
MPQPPFTRPAMPSRFLMPLLFAAAAALPCTSVLAAPATAEDSAQGEALSPPASPKEGKGAYFSDWFNQDLTLIGSKDISF
GPKPNDDIYLEYEYFGRKGPFELYGYVDVPKILGIGNDNDKGVWDHGSPLFMEHEPRISIDYLAGRSLAVGPFKEWYVAF
DWIYDHGSNTANRANTLYSGLGTDIDTHSRVNLSANFYGRYQWENYGASNEYSWDGYRAQLKYIVPISTFDNGASLTYIG
FTNFDFGSDLKNDPARTGNSTVATNVLLYAFTHLRFTLVGRYFHNGGNWQDGSELNFGDGNFRARSDGWGYYAGVGYQF
>Mature_318_residues
PQPPFTRPAMPSRFLMPLLFAAAAALPCTSVLAAPATAEDSAQGEALSPPASPKEGKGAYFSDWFNQDLTLIGSKDISFG
PKPNDDIYLEYEYFGRKGPFELYGYVDVPKILGIGNDNDKGVWDHGSPLFMEHEPRISIDYLAGRSLAVGPFKEWYVAFD
WIYDHGSNTANRANTLYSGLGTDIDTHSRVNLSANFYGRYQWENYGASNEYSWDGYRAQLKYIVPISTFDNGASLTYIGF
TNFDFGSDLKNDPARTGNSTVATNVLLYAFTHLRFTLVGRYFHNGGNWQDGSELNFGDGNFRARSDGWGYYAGVGYQF

Specific function: Constitutes the receptor for colicin K and phage T6, and functions as substrate-specific channel for nucleosides and deoxynucleosides [H]

COG id: COG3248

COG function: function code M; Nucleoside-binding outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786612, Length=275, Percent_Identity=51.2727272727273, Blast_Score=277, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003055
- InterPro:   IPR018013 [H]

Pfam domain/function: PF03502 Channel_Tsx [H]

EC number: NA

Molecular weight: Translated: 35499; Mature: 35368

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPPFTRPAMPSRFLMPLLFAAAAALPCTSVLAAPATAEDSAQGEALSPPASPKEGKGA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
YFSDWFNQDLTLIGSKDISFGPKPNDDIYLEYEYFGRKGPFELYGYVDVPKILGIGNDND
CHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECHHEEECCCCCC
KGVWDHGSPLFMEHEPRISIDYLAGRSLAVGPFKEWYVAFDWIYDHGSNTANRANTLYSG
CCCCCCCCEEEEECCCCEEEEEECCCCEECCCCHHEEEEEEEEEECCCCCCHHHHHHHHH
LGTDIDTHSRVNLSANFYGRYQWENYGASNEYSWDGYRAQLKYIVPISTFDNGASLTYIG
CCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEECCCCCEEEEEE
FTNFDFGSDLKNDPARTGNSTVATNVLLYAFTHLRFTLVGRYFHNGGNWQDGSELNFGDG
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCEECCCCC
NFRARSDGWGYYAGVGYQF
CEEECCCCCEEEEECCCCC
>Mature Secondary Structure 
PQPPFTRPAMPSRFLMPLLFAAAAALPCTSVLAAPATAEDSAQGEALSPPASPKEGKGA
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
YFSDWFNQDLTLIGSKDISFGPKPNDDIYLEYEYFGRKGPFELYGYVDVPKILGIGNDND
CHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEECHHEEECCCCCC
KGVWDHGSPLFMEHEPRISIDYLAGRSLAVGPFKEWYVAFDWIYDHGSNTANRANTLYSG
CCCCCCCCEEEEECCCCEEEEEECCCCEECCCCHHEEEEEEEEEECCCCCCHHHHHHHHH
LGTDIDTHSRVNLSANFYGRYQWENYGASNEYSWDGYRAQLKYIVPISTFDNGASLTYIG
CCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEECCCCCEEEEEE
FTNFDFGSDLKNDPARTGNSTVATNVLLYAFTHLRFTLVGRYFHNGGNWQDGSELNFGDG
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCEECCCCC
NFRARSDGWGYYAGVGYQF
CEEECCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]