Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 66047004

GI number: 66047004

Start: 4495335

End: 4495772

Strand: Reverse

Name: tadA [H]

Synonym: Psyr_3776

Alternate gene names: 66047004

Gene position: 4495772-4495335 (Counterclockwise)

Preceding gene: 66047005

Following gene: 66047003

Centisome position: 73.78

GC content: 57.99

Gene sequence:

>438_bases
ATGGACGCATTCATGCAGGCAGCATTCGATGAGGCGCAACTCGGGCTGAAGGAAGGCGGAATCCCTATCGGCTCGGTCAT
CGTCCACGGCGGCAAAATCATCGGTCGAGGCCACAACCGTCGTGTACAAGAGGGCAGTGCGACGAAGCATGGCGAGATGG
ATGCGCTGGAAAATGCCGGTCGCCAGCCTGCCAGTGTCTACCGTGACTCGGTCCTCTACACCACGCTGTCGCCTTGTGCG
ATGTGCAGCGGTGCGATCCTGCTCTACGGGATTCGCAAAGTGATCATCGGTGAGAATGAGTCCTTCATGGGCGAGGAAGA
ACTGCTGCGCTCGCGTGGCGTGCAGATCGACGTGCTGGATAACCCTGAGTGCACACACATGATGAAAGACTTTATCGCCA
GCAAGCCCGAACTGTGGAACGAAGACATCGGCGAGTGA

Upstream 100 bases:

>100_bases
TCATCGGAGCTGCTGGGACAATTTGTCAGTCGTGCGCTGAGCAATGCCGAGGCAGCACTGCGACGCTGACAGCTATTTTG
ACGAGACGAGGCAAAAAAAC

Downstream 100 bases:

>100_bases
ATCCCGCGTCTTGTCAGCCCCACGCTCCGCGCTCATCGTAAATCTGACTGCTCATCGTGCCAATGCTCCGCATTGGCATG
CAGTTCGTGACGCTCCTGCC

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDAFMQAAFDEAQLGLKEGGIPIGSVIVHGGKIIGRGHNRRVQEGSATKHGEMDALENAGRQPASVYRDSVLYTTLSPCA
MCSGAILLYGIRKVIIGENESFMGEEELLRSRGVQIDVLDNPECTHMMKDFIASKPELWNEDIGE

Sequences:

>Translated_145_residues
MDAFMQAAFDEAQLGLKEGGIPIGSVIVHGGKIIGRGHNRRVQEGSATKHGEMDALENAGRQPASVYRDSVLYTTLSPCA
MCSGAILLYGIRKVIIGENESFMGEEELLRSRGVQIDVLDNPECTHMMKDFIASKPELWNEDIGE
>Mature_145_residues
MDAFMQAAFDEAQLGLKEGGIPIGSVIVHGGKIIGRGHNRRVQEGSATKHGEMDALENAGRQPASVYRDSVLYTTLSPCA
MCSGAILLYGIRKVIIGENESFMGEEELLRSRGVQIDVLDNPECTHMMKDFIASKPELWNEDIGE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=111, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=31.5068493150685, Blast_Score=74, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17541138, Length=107, Percent_Identity=41.1214953271028, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=37.5, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=144, Percent_Identity=51.3888888888889, Blast_Score=159, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21355527, Length=113, Percent_Identity=36.283185840708, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15838; Mature: 15838

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFMQAAFDEAQLGLKEGGIPIGSVIVHGGKIIGRGHNRRVQEGSATKHGEMDALENAG
CCHHHHHHHHHHHHCHHCCCCCHHHEEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHCC
RQPASVYRDSVLYTTLSPCAMCSGAILLYGIRKVIIGENESFMGEEELLRSRGVQIDVLD
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEC
NPECTHMMKDFIASKPELWNEDIGE
CCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDAFMQAAFDEAQLGLKEGGIPIGSVIVHGGKIIGRGHNRRVQEGSATKHGEMDALENAG
CCHHHHHHHHHHHHCHHCCCCCHHHEEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHCC
RQPASVYRDSVLYTTLSPCAMCSGAILLYGIRKVIIGENESFMGEEELLRSRGVQIDVLD
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEC
NPECTHMMKDFIASKPELWNEDIGE
CCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]