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The map label for this gene is aer [H]

Identifier: 66046963

GI number: 66046963

Start: 4446990

End: 4448555

Strand: Reverse

Name: aer [H]

Synonym: Psyr_3735

Alternate gene names: 66046963

Gene position: 4448555-4446990 (Counterclockwise)

Preceding gene: 66046964

Following gene: 66046962

Centisome position: 73.0

GC content: 61.75

Gene sequence:

>1566_bases
ATGCGCGTCAACATGCCTATCACGCAGACTGAGCGGACTTTTCCGGCCTCTGAACGTCTGATCTCTACCACCGACCTCAA
CAGCCACATCACTTACTGCAACGACGCTTTCGTCACCCTGAGCGGCTTTACTCGCGAAGAGCTGGTCGGGCAGCCGCATA
ACCTGGTGCGCCACCCGGACATGCCAGCCTCGGTGTTCGCGCATATGTGGGAAACCATCAAACAGGGCAAGCCGTGGATG
GGCGTGGTCAAGAATCGCTCCAAGCAGGGCGATTACTACTGGGTCAGCGCTTATGTAACCGCGGTGTACGAAAACGGCCG
TATCGTCGGGTACGAGTCGGTGCGCTCGCTGCCGACCCGCGATCAGGTGCGGCGTGCCGAAGCACTCTATGCGCGGTTGC
GGGCTGGCAAGGCGGCGGTGTCCGCCAGCAGCTCGGCGGCCTATCACCTGATTCGTCAGTTACCGATGATTCTCTGCGCG
CTTGCGCTGGCTGTGGGTGTTTACCTGCTCGACGATTTGCCGTCGATCATCATGATCCCGATTGTGATGGTCGTGTTGGG
CGTTTTTCTTGAAGTACGTCAGCGCAGCAGCATCCGCAAAACCCTTGAGGAACACCCCAAGGCCTTCACCAGTGCACTGA
TTGCGCTGACCTACAGCGACAGTCGCGGCCCGCAGGCGCAGCTCGACCTGGCCATGCTCAGCGAAGAGGCGCGCCTGCAA
ACAGCCCTGACGCGACTGGCGGATACTGGCGAAAGCGTGCGCCAGCATGCCGGTCGGTCAGCACAATTGTCCCTGCGCCA
GGCCGAGTCGCTGGATCAGCAGCGCAGCGAGGCCGATCAGTCAGCCACGGCTATCAACCAGATGGCGGCGACCATTCAGG
AAGTCACCCACAACGTGCAGAACACTGCCCATGCTGCCGAAGAGGCCGACAAGCTGGCACAACAGGGGCGTGGCCTGGCC
GATGAAAGCCTGTTGGCGATTCGGCACATGGCCACCTCGGTTACCGACATTGGCAACGCCGTGGGGGAACTGGCTGATGC
GACTCAATCGATCGGCAGTGTGGTCGATGTGATCACCTCGATCGCTCAGCAAACCAATTTGCTGGCGCTCAACGCAGCCA
TCGAAGCGGCGCGTGCCGGTGAACAGGGACGTGGTTTTGCGGTGGTGGCCGACGAGGTACGCTCGCTGGCGTCTCGCACG
CAGTCGTCGACCGAGCAGATCCAGCAAATCATCACCTCGCTGCGCGATGGCGCCGACCGGGCGGTAAAGACCGCCAGCAA
GGGCGAGCAGATCTCTCAGGAGAGTGTCGCCAGCGTTGAAGCCGTGCAGAAGGCGCTGGATGGCATCAGCCAGTCGGTGA
CCCGCATCACCGGCATGAGCCAGCAGATGGCGTCGGCGTCTGAAGAACAGAGCCACGTCGCGGAAACCATCAGCCAGCAA
ATCACCCGCATCGCGCAACTCTGCGACGAGAGCGCCAGCCAGGCGCAGCAAGGCTCGCAGATCAGCAGCGAGCTGGAAGA
AATGGCGCAGTACCTGCACAGTCTGGCGGAACGGTTCAGCCGCTAG

Upstream 100 bases:

>100_bases
GGCGATAACAGTGCATCATGACTATCGGCTGTCTTTGAAACGCTGTGCTACACCTTCAACAACTGCCCTGAGTATCAGCA
TTATCACGGAGCGATTCTTA

Downstream 100 bases:

>100_bases
GCAGGCCACTCCCTGGATAGGACGCGGAGCGTCCTGAACGGCATTACCACGCGGAGCGTGGGAACGATATCGACCGCCAC
TTATTGTGCCCATCGCTTCG

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MRVNMPITQTERTFPASERLISTTDLNSHITYCNDAFVTLSGFTREELVGQPHNLVRHPDMPASVFAHMWETIKQGKPWM
GVVKNRSKQGDYYWVSAYVTAVYENGRIVGYESVRSLPTRDQVRRAEALYARLRAGKAAVSASSSAAYHLIRQLPMILCA
LALAVGVYLLDDLPSIIMIPIVMVVLGVFLEVRQRSSIRKTLEEHPKAFTSALIALTYSDSRGPQAQLDLAMLSEEARLQ
TALTRLADTGESVRQHAGRSAQLSLRQAESLDQQRSEADQSATAINQMAATIQEVTHNVQNTAHAAEEADKLAQQGRGLA
DESLLAIRHMATSVTDIGNAVGELADATQSIGSVVDVITSIAQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRT
QSSTEQIQQIITSLRDGADRAVKTASKGEQISQESVASVEAVQKALDGISQSVTRITGMSQQMASASEEQSHVAETISQQ
ITRIAQLCDESASQAQQGSQISSELEEMAQYLHSLAERFSR

Sequences:

>Translated_521_residues
MRVNMPITQTERTFPASERLISTTDLNSHITYCNDAFVTLSGFTREELVGQPHNLVRHPDMPASVFAHMWETIKQGKPWM
GVVKNRSKQGDYYWVSAYVTAVYENGRIVGYESVRSLPTRDQVRRAEALYARLRAGKAAVSASSSAAYHLIRQLPMILCA
LALAVGVYLLDDLPSIIMIPIVMVVLGVFLEVRQRSSIRKTLEEHPKAFTSALIALTYSDSRGPQAQLDLAMLSEEARLQ
TALTRLADTGESVRQHAGRSAQLSLRQAESLDQQRSEADQSATAINQMAATIQEVTHNVQNTAHAAEEADKLAQQGRGLA
DESLLAIRHMATSVTDIGNAVGELADATQSIGSVVDVITSIAQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRT
QSSTEQIQQIITSLRDGADRAVKTASKGEQISQESVASVEAVQKALDGISQSVTRITGMSQQMASASEEQSHVAETISQQ
ITRIAQLCDESASQAQQGSQISSELEEMAQYLHSLAERFSR
>Mature_521_residues
MRVNMPITQTERTFPASERLISTTDLNSHITYCNDAFVTLSGFTREELVGQPHNLVRHPDMPASVFAHMWETIKQGKPWM
GVVKNRSKQGDYYWVSAYVTAVYENGRIVGYESVRSLPTRDQVRRAEALYARLRAGKAAVSASSSAAYHLIRQLPMILCA
LALAVGVYLLDDLPSIIMIPIVMVVLGVFLEVRQRSSIRKTLEEHPKAFTSALIALTYSDSRGPQAQLDLAMLSEEARLQ
TALTRLADTGESVRQHAGRSAQLSLRQAESLDQQRSEADQSATAINQMAATIQEVTHNVQNTAHAAEEADKLAQQGRGLA
DESLLAIRHMATSVTDIGNAVGELADATQSIGSVVDVITSIAQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRT
QSSTEQIQQIITSLRDGADRAVKTASKGEQISQESVASVEAVQKALDGISQSVTRITGMSQQMASASEEQSHVAETISQQ
ITRIAQLCDESASQAQQGSQISSELEEMAQYLHSLAERFSR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=532, Percent_Identity=31.5789473684211, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1788195, Length=218, Percent_Identity=36.697247706422, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788194, Length=245, Percent_Identity=34.2857142857143, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1787690, Length=247, Percent_Identity=35.2226720647773, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI2367378, Length=201, Percent_Identity=35.8208955223881, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56621; Mature: 56621

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNMPITQTERTFPASERLISTTDLNSHITYCNDAFVTLSGFTREELVGQPHNLVRHPD
CCCCCCCCCCCCCCCHHHHHEECCCCCCCCCEECCCEEEECCCCHHHHCCCCHHHCCCCC
MPASVFAHMWETIKQGKPWMGVVKNRSKQGDYYWVSAYVTAVYENGRIVGYESVRSLPTR
CCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEHHHHHHHHHCCCCEEEHHHHHCCCCH
DQVRRAEALYARLRAGKAAVSASSSAAYHLIRQLPMILCALALAVGVYLLDDLPSIIMIP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IVMVVLGVFLEVRQRSSIRKTLEEHPKAFTSALIALTYSDSRGPQAQLDLAMLSEEARLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHH
TALTRLADTGESVRQHAGRSAQLSLRQAESLDQQRSEADQSATAINQMAATIQEVTHNVQ
HHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTAHAAEEADKLAQQGRGLADESLLAIRHMATSVTDIGNAVGELADATQSIGSVVDVITS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQSSTEQIQQIITSLRDGADR
HHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AVKTASKGEQISQESVASVEAVQKALDGISQSVTRITGMSQQMASASEEQSHVAETISQQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITRIAQLCDESASQAQQGSQISSELEEMAQYLHSLAERFSR
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVNMPITQTERTFPASERLISTTDLNSHITYCNDAFVTLSGFTREELVGQPHNLVRHPD
CCCCCCCCCCCCCCCHHHHHEECCCCCCCCCEECCCEEEECCCCHHHHCCCCHHHCCCCC
MPASVFAHMWETIKQGKPWMGVVKNRSKQGDYYWVSAYVTAVYENGRIVGYESVRSLPTR
CCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEHHHHHHHHHCCCCEEEHHHHHCCCCH
DQVRRAEALYARLRAGKAAVSASSSAAYHLIRQLPMILCALALAVGVYLLDDLPSIIMIP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IVMVVLGVFLEVRQRSSIRKTLEEHPKAFTSALIALTYSDSRGPQAQLDLAMLSEEARLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHH
TALTRLADTGESVRQHAGRSAQLSLRQAESLDQQRSEADQSATAINQMAATIQEVTHNVQ
HHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTAHAAEEADKLAQQGRGLADESLLAIRHMATSVTDIGNAVGELADATQSIGSVVDVITS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQSSTEQIQQIITSLRDGADR
HHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AVKTASKGEQISQESVASVEAVQKALDGISQSVTRITGMSQQMASASEEQSHVAETISQQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITRIAQLCDESASQAQQGSQISSELEEMAQYLHSLAERFSR
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]