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The map label for this gene is rstA [H]

Identifier: 66046945

GI number: 66046945

Start: 4402990

End: 4403733

Strand: Reverse

Name: rstA [H]

Synonym: Psyr_3716

Alternate gene names: 66046945

Gene position: 4403733-4402990 (Counterclockwise)

Preceding gene: 66046951

Following gene: 66046944

Centisome position: 72.27

GC content: 64.65

Gene sequence:

>744_bases
ATGGCTGTGGAACCACACACCTGGCACGTATTGATCGTCGAGGATGACCAGCGACTGGCCGAACTGACCAGCGATTACCT
GCAGAACCACGGCCTGCGCGTGAGCATCGAAGGCGACGGCGCGCTGGCGGCAGCGCGGATCATCGCCGAGCAGCCGGATC
TGGTGATTCTCGACCTGATGCTGCCCGGCGAGGACGGTTTCAGCATCTGCCGCAGTGTGCGTGACCGCTACGACGGGCCG
ATTCTGATGCTCACCGCGCGCACTGACGACACCGACCATATAGAAGGACTCGACACCGGCGCCGACGATTTCGTCTGCAA
ACCGGTGCATCCGCGCGTGCTGCTGGCGCGTATCAAAGCCCTGCTGCGCCGCAGTGAAGCGCCGCAGGTGCCGGCTGCCG
AGCTGCGCCGTCTGGTGTTCGGGCCGTTGGTGGTGGACAACGCACTGCGTGAGGCCTGGCTTCGCGAGCAGAGCATCGAG
CTGACCGGTGCCGAGTTCGACCTGCTGTGGCTGCTGGTGGCCAACGCCGGGCGCACGCTGTCCCGCGAAGAGATTTTCAC
CGCGCTGCGCGGTGTGGGGTACGACGGGCAGGATCGCTCCATCGATGTGCGTATCTCGCGTATCCGCCCGAAAATCGGCG
ACGATCCCATTCATCCGCGTCTGATCAAGACCGTGCGCAGCAAGGGCTATCTGTTTGTGCCCGAAGCGGCGCAGGACATG
AGCGGCCACGTGTTCAGCGGCTGA

Upstream 100 bases:

>100_bases
TGTCGTGTGATCCGCGCAAGGGTTGCTACACTCGCCTGCGACGCGATGCCGCAACCCCTGCGTTGCAAAAACAAAAAGCG
GTCGATAACGACAAGGAAAG

Downstream 100 bases:

>100_bases
CCTGATGAATTCGATCTTTCTGCGCATCTACGGTGGCGTACTGTGCGTATTGGTGCTGGTCGCGCTGCTCGGCGTGCTGG
CCCTGCATGTGCTCAACCAG

Product: response regulator receiver:transcriptional regulatory protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MAVEPHTWHVLIVEDDQRLAELTSDYLQNHGLRVSIEGDGALAAARIIAEQPDLVILDLMLPGEDGFSICRSVRDRYDGP
ILMLTARTDDTDHIEGLDTGADDFVCKPVHPRVLLARIKALLRRSEAPQVPAAELRRLVFGPLVVDNALREAWLREQSIE
LTGAEFDLLWLLVANAGRTLSREEIFTALRGVGYDGQDRSIDVRISRIRPKIGDDPIHPRLIKTVRSKGYLFVPEAAQDM
SGHVFSG

Sequences:

>Translated_247_residues
MAVEPHTWHVLIVEDDQRLAELTSDYLQNHGLRVSIEGDGALAAARIIAEQPDLVILDLMLPGEDGFSICRSVRDRYDGP
ILMLTARTDDTDHIEGLDTGADDFVCKPVHPRVLLARIKALLRRSEAPQVPAAELRRLVFGPLVVDNALREAWLREQSIE
LTGAEFDLLWLLVANAGRTLSREEIFTALRGVGYDGQDRSIDVRISRIRPKIGDDPIHPRLIKTVRSKGYLFVPEAAQDM
SGHVFSG
>Mature_246_residues
AVEPHTWHVLIVEDDQRLAELTSDYLQNHGLRVSIEGDGALAAARIIAEQPDLVILDLMLPGEDGFSICRSVRDRYDGPI
LMLTARTDDTDHIEGLDTGADDFVCKPVHPRVLLARIKALLRRSEAPQVPAAELRRLVFGPLVVDNALREAWLREQSIEL
TGAEFDLLWLLVANAGRTLSREEIFTALRGVGYDGQDRSIDVRISRIRPKIGDDPIHPRLIKTVRSKGYLFVPEAAQDMS
GHVFSG

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=43.1623931623932, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=41.1016949152542, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=35.1464435146443, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=36.2068965517241, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=33.6283185840708, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=34.7826086956522, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.4978165938865, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=35.6828193832599, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=34.375, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=32.9113924050633, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=30.6034482758621, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.1351351351351, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27517; Mature: 27386

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVEPHTWHVLIVEDDQRLAELTSDYLQNHGLRVSIEGDGALAAARIIAEQPDLVILDLM
CCCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEEEE
LPGEDGFSICRSVRDRYDGPILMLTARTDDTDHIEGLDTGADDFVCKPVHPRVLLARIKA
ECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHH
LLRRSEAPQVPAAELRRLVFGPLVVDNALREAWLREQSIELTGAEFDLLWLLVANAGRTL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHEEECCCCCCC
SREEIFTALRGVGYDGQDRSIDVRISRIRPKIGDDPIHPRLIKTVRSKGYLFVPEAAQDM
CHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEECCHHHCC
SGHVFSG
CCCCCCC
>Mature Secondary Structure 
AVEPHTWHVLIVEDDQRLAELTSDYLQNHGLRVSIEGDGALAAARIIAEQPDLVILDLM
CCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEEEEEEE
LPGEDGFSICRSVRDRYDGPILMLTARTDDTDHIEGLDTGADDFVCKPVHPRVLLARIKA
ECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHH
LLRRSEAPQVPAAELRRLVFGPLVVDNALREAWLREQSIELTGAEFDLLWLLVANAGRTL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHEEECCCCCCC
SREEIFTALRGVGYDGQDRSIDVRISRIRPKIGDDPIHPRLIKTVRSKGYLFVPEAAQDM
CHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEECCHHHCC
SGHVFSG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]