Click here to switch to the map view.

The map label for this gene is rstB [H]

Identifier: 66046944

GI number: 66046944

Start: 4401375

End: 4402985

Strand: Reverse

Name: rstB [H]

Synonym: Psyr_3715

Alternate gene names: 66046944

Gene position: 4402985-4401375 (Counterclockwise)

Preceding gene: 66046945

Following gene: 66046943

Centisome position: 72.25

GC content: 64.68

Gene sequence:

>1611_bases
ATGAATTCGATCTTTCTGCGCATCTACGGTGGCGTACTGTGCGTATTGGTGCTGGTCGCGCTGCTCGGCGTGCTGGCCCT
GCATGTGCTCAACCAGTCGCGCGGCGAGCAGTACCGCGAGCGCCTGGCCCATGGCACCTTTACGATCATGGCCGACAATC
TGCTGCCCCTCGATGGCATCGAACGGCGCCGCGCCCTGGCAGTCTGGGAGCGACTGCTGGGCATTCCCCTGAGTCTGCAA
ACCCTTGAACAGGCTCACCTCGACAGCAGCGCACTGGGGCAACTGGCGCGCGGCAAGGTAGTGGTCGAACAGATCGGGCC
GCACGCTGCCAGGGTTTATCGTCAGTTGAGCGACAAGGAGCCACTGTTGCTGACCGGCGAAGTGCAGCAGATCACCGAAC
AACTGGCGAGAGCCACTATTTACCTGCTGATCGATGAACTGGTGCGCTTTCCGGTCGACGAGCAACCGGCGCGCCTGCAG
GCCCTGCGCAGCGACAAGGGGTTCGGTTTCGACCTGCACCTGCTGGCGCTGGATCAGGCTGATCTGGACGATGACCAGCG
CCGCCGCGTCTATGAGGGCGATACGGTCATGGCGCTGGGCAAGGGCGGCGATTCGATCCGCGTGCTGGCCGGGATCGTCG
ACACCAACTGGGTGCTGGAAATCGGCCCGCTGTACCAGATGAACCCCTATCCACTGCATTGGCTGCTGCTGATCGCCTTG
ATGGGCCTGTGTCTGATCGGTCTGGTGGTGTACTTGCTGGTGCGGCGTCTGGAGCGACGGGTGCTGGAGCTGGAAGCGGC
GGCCACGCAGATTGCCCAAGGCAGCCTGCACAGCCGCGTGCCGACCGAAGGCTCCGACTCGGTGGGGCGTGTGGCGGCGG
CGTTCAACAGCATGGCCGAACACCTGCAGCGCTCATTGATGATCCAGCGTGAACTGGTGCGCGCGGTGTCTCACGAACTG
CGCACGCCGGTGGCGCGTCTGCGTTTCGGTCTGGAGATGGTCAGCGACGCCGCGACTCCCGAGGCGCGGCGCAAATACAT
GCGCGGCATGGACAGCGATATTCAGGACCTCGACAAACTGGTCGATGAGATGCTCACCTACGCGCGCCTTGAGCAAGGCG
CGCCGACCCTGAATTTCCAGCGTGTCGACCTGGATGCGCTGATCGATCAGGTGATCGCCGAACTGGCGCCACTGCGCGCC
GATGTGCGGGTTTCGCGGGGCGAATGCCTGAGGGCCGAAGAGGGCGAGGCTGCCTGGGTCGAGGGCGAGCCGCGCTATCT
GCACCGCGCCGTGCAGAACCTGGTGAGCAACGCGCTGCGCCATGCCGACAACGAGGTGCGTATCAGTTATCGGCTCGAGG
CGCAGCAGTGCCGTATCGACGTGGACGACGATGGCCCTGGCGTGCCGGAGCAGGCCTGGGATCAGATTTTCACGCCGTTC
ATGCGCATCGATGACAGCCGCACCCGTGCCTCGGGCGGGCATGGGCTGGGTCTGTCGATCGTGCGGCGGATCATCCATTG
GCATGAAGGCCGCGCGCTGATCGGACACAGCGTCAGCCTGGGCGGAGCATGCTTCAGCCTGACCTGGCCGCGCACGCAGG
TGCCGCGTTGA

Upstream 100 bases:

>100_bases
ATTCATCCGCGTCTGATCAAGACCGTGCGCAGCAAGGGCTATCTGTTTGTGCCCGAAGCGGCGCAGGACATGAGCGGCCA
CGTGTTCAGCGGCTGACCTG

Downstream 100 bases:

>100_bases
GCTTGCCTTTGTTTGCCGGGCCATTTGCGCGGTTCGGGCGGACCTTGCTGACGGCGGATGATCCGCGTCCGGTGATGACG
TTGCCTGATCTGCTGCGCCC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MNSIFLRIYGGVLCVLVLVALLGVLALHVLNQSRGEQYRERLAHGTFTIMADNLLPLDGIERRRALAVWERLLGIPLSLQ
TLEQAHLDSSALGQLARGKVVVEQIGPHAARVYRQLSDKEPLLLTGEVQQITEQLARATIYLLIDELVRFPVDEQPARLQ
ALRSDKGFGFDLHLLALDQADLDDDQRRRVYEGDTVMALGKGGDSIRVLAGIVDTNWVLEIGPLYQMNPYPLHWLLLIAL
MGLCLIGLVVYLLVRRLERRVLELEAAATQIAQGSLHSRVPTEGSDSVGRVAAAFNSMAEHLQRSLMIQRELVRAVSHEL
RTPVARLRFGLEMVSDAATPEARRKYMRGMDSDIQDLDKLVDEMLTYARLEQGAPTLNFQRVDLDALIDQVIAELAPLRA
DVRVSRGECLRAEEGEAAWVEGEPRYLHRAVQNLVSNALRHADNEVRISYRLEAQQCRIDVDDDGPGVPEQAWDQIFTPF
MRIDDSRTRASGGHGLGLSIVRRIIHWHEGRALIGHSVSLGGACFSLTWPRTQVPR

Sequences:

>Translated_536_residues
MNSIFLRIYGGVLCVLVLVALLGVLALHVLNQSRGEQYRERLAHGTFTIMADNLLPLDGIERRRALAVWERLLGIPLSLQ
TLEQAHLDSSALGQLARGKVVVEQIGPHAARVYRQLSDKEPLLLTGEVQQITEQLARATIYLLIDELVRFPVDEQPARLQ
ALRSDKGFGFDLHLLALDQADLDDDQRRRVYEGDTVMALGKGGDSIRVLAGIVDTNWVLEIGPLYQMNPYPLHWLLLIAL
MGLCLIGLVVYLLVRRLERRVLELEAAATQIAQGSLHSRVPTEGSDSVGRVAAAFNSMAEHLQRSLMIQRELVRAVSHEL
RTPVARLRFGLEMVSDAATPEARRKYMRGMDSDIQDLDKLVDEMLTYARLEQGAPTLNFQRVDLDALIDQVIAELAPLRA
DVRVSRGECLRAEEGEAAWVEGEPRYLHRAVQNLVSNALRHADNEVRISYRLEAQQCRIDVDDDGPGVPEQAWDQIFTPF
MRIDDSRTRASGGHGLGLSIVRRIIHWHEGRALIGHSVSLGGACFSLTWPRTQVPR
>Mature_536_residues
MNSIFLRIYGGVLCVLVLVALLGVLALHVLNQSRGEQYRERLAHGTFTIMADNLLPLDGIERRRALAVWERLLGIPLSLQ
TLEQAHLDSSALGQLARGKVVVEQIGPHAARVYRQLSDKEPLLLTGEVQQITEQLARATIYLLIDELVRFPVDEQPARLQ
ALRSDKGFGFDLHLLALDQADLDDDQRRRVYEGDTVMALGKGGDSIRVLAGIVDTNWVLEIGPLYQMNPYPLHWLLLIAL
MGLCLIGLVVYLLVRRLERRVLELEAAATQIAQGSLHSRVPTEGSDSVGRVAAAFNSMAEHLQRSLMIQRELVRAVSHEL
RTPVARLRFGLEMVSDAATPEARRKYMRGMDSDIQDLDKLVDEMLTYARLEQGAPTLNFQRVDLDALIDQVIAELAPLRA
DVRVSRGECLRAEEGEAAWVEGEPRYLHRAVQNLVSNALRHADNEVRISYRLEAQQCRIDVDDDGPGVPEQAWDQIFTPF
MRIDDSRTRASGGHGLGLSIVRRIIHWHEGRALIGHSVSLGGACFSLTWPRTQVPR

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=406, Percent_Identity=31.7733990147783, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1790346, Length=250, Percent_Identity=32.8, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1789808, Length=281, Percent_Identity=31.6725978647687, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788393, Length=266, Percent_Identity=31.5789473684211, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=30.6666666666667, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082128, Length=305, Percent_Identity=29.1803278688525, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081816, Length=397, Percent_Identity=23.6775818639798, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786783, Length=374, Percent_Identity=25.4010695187166, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790551, Length=295, Percent_Identity=28.8135593220339, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=29.535864978903, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=23.1884057971014, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=24.8888888888889, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=26.3829787234043, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790861, Length=254, Percent_Identity=26.3779527559055, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=306, Percent_Identity=23.8562091503268, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=27.0161290322581, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789403, Length=252, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=24.4635193133047, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59986; Mature: 59986

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIFLRIYGGVLCVLVLVALLGVLALHVLNQSRGEQYRERLAHGTFTIMADNLLPLDGI
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCH
ERRRALAVWERLLGIPLSLQTLEQAHLDSSALGQLARGKVVVEQIGPHAARVYRQLSDKE
HHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHCHHHHHHHHHHCCCC
PLLLTGEVQQITEQLARATIYLLIDELVRFPVDEQPARLQALRSDKGFGFDLHLLALDQA
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEECCC
DLDDDQRRRVYEGDTVMALGKGGDSIRVLAGIVDTNWVLEIGPLYQMNPYPLHWLLLIAL
CCCCHHHHHEECCCEEEEECCCCCCEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHH
MGLCLIGLVVYLLVRRLERRVLELEAAATQIAQGSLHSRVPTEGSDSVGRVAAAFNSMAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHH
HLQRSLMIQRELVRAVSHELRTPVARLRFGLEMVSDAATPEARRKYMRGMDSDIQDLDKL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHH
VDEMLTYARLEQGAPTLNFQRVDLDALIDQVIAELAPLRADVRVSRGECLRAEEGEAAWV
HHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEE
EGEPRYLHRAVQNLVSNALRHADNEVRISYRLEAQQCRIDVDDDGPGVPEQAWDQIFTPF
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCEEECCCCCCCCCHHHHHHHHHHH
MRIDDSRTRASGGHGLGLSIVRRIIHWHEGRALIGHSVSLGGACFSLTWPRTQVPR
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MNSIFLRIYGGVLCVLVLVALLGVLALHVLNQSRGEQYRERLAHGTFTIMADNLLPLDGI
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCH
ERRRALAVWERLLGIPLSLQTLEQAHLDSSALGQLARGKVVVEQIGPHAARVYRQLSDKE
HHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHCHHHHHHHHHHCCCC
PLLLTGEVQQITEQLARATIYLLIDELVRFPVDEQPARLQALRSDKGFGFDLHLLALDQA
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEECCC
DLDDDQRRRVYEGDTVMALGKGGDSIRVLAGIVDTNWVLEIGPLYQMNPYPLHWLLLIAL
CCCCHHHHHEECCCEEEEECCCCCCEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHH
MGLCLIGLVVYLLVRRLERRVLELEAAATQIAQGSLHSRVPTEGSDSVGRVAAAFNSMAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHH
HLQRSLMIQRELVRAVSHELRTPVARLRFGLEMVSDAATPEARRKYMRGMDSDIQDLDKL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHH
VDEMLTYARLEQGAPTLNFQRVDLDALIDQVIAELAPLRADVRVSRGECLRAEEGEAAWV
HHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEE
EGEPRYLHRAVQNLVSNALRHADNEVRISYRLEAQQCRIDVDDDGPGVPEQAWDQIFTPF
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCEEECCCCCCCCCHHHHHHHHHHH
MRIDDSRTRASGGHGLGLSIVRRIIHWHEGRALIGHSVSLGGACFSLTWPRTQVPR
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]