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The map label for this gene is hda [H]

Identifier: 66046915

GI number: 66046915

Start: 4372196

End: 4372981

Strand: Reverse

Name: hda [H]

Synonym: Psyr_3686

Alternate gene names: 66046915

Gene position: 4372981-4372196 (Counterclockwise)

Preceding gene: 66046916

Following gene: 66046914

Centisome position: 71.76

GC content: 60.18

Gene sequence:

>786_bases
TTGTGCGACCAGCGTCACGGGTATAAACTTTGCGCTCTTTACACAGAGGCCCTTGACGGTTTGCATGAGCCGTTAGTCAG
CATGAAACCGATTCAGCTGCCCCTGAGTGTGCGTCTGCGTGATGACGCCACTTTCGTCAATTACTATCCAGGCGCCAACG
CCGCTGCACTCGGCTATGTCGAGCGGCTGTGCGAAGCCGACGCTGGCTGGACCGAAAGCCTCATCTACCTGTGGGGCAAG
GACGGGGTAGGGCGCACGCACCTGCTGCAGGCTGCCTGCCTGCGTTTCGAACAGTTGGGCGAGCCTGCGGTGTATCTGCC
GCTGGCCGAAGTCATAGATGAAGGCATCGAGCTGTTCGATCATCTGGAGCAGTACGAACTGGTGTGTCTGGACGACCTGC
AGGCGATCGTCGGCAAGCCGGACTGGGAAGAAGCGCTGTTTCATCTGTTCAATCGCCTGCGTGACAGCGGCCGTCGTCTG
CTGATTGCCGCGTCCAAATCGCCCCGCGAACTGCCGGTAAAGCTTCCCGACCTGAAATCACGCCTGACCATGGCGCTGGT
GTTCCAGATGCGCGGGCTGTCCGACGAGGACAAGCTGCGTGCCCTGCAACTGCGTGCTTCACGGCGCGGCCTGCACCTGA
CCGACGATGTCGGGCATTTCATCCTGACGCGCGGTACACGCAGCATGAGCGCGTTGTTCGAATTGCTCGAGCGCCTCGAT
CAGGCGTCACTCCAGGAAAAGCGCAAGCTGACCATTCCCTTCCTTAAAGAGACCCTCGGGTGGTAG

Upstream 100 bases:

>100_bases
GCTCATGCCTTGAGGGTATGCGCCCCTTCAAACGCCCCGTACTGGGCGGCGCTTCACTCACCCTGACGCAAACCTTTGAT
TTTGCTTGAGGTCTGTCGCA

Downstream 100 bases:

>100_bases
ATCAGGCGCTGTTGATGCAGACGGCGGCTGCCTTGCGCCATGCAAAACGGATTCTGGTGATCACCGGGGCGGGGCTGTCT
GCCGATTCGGGGCTGCCGAC

Product: DNA replication initiation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MCDQRHGYKLCALYTEALDGLHEPLVSMKPIQLPLSVRLRDDATFVNYYPGANAAALGYVERLCEADAGWTESLIYLWGK
DGVGRTHLLQAACLRFEQLGEPAVYLPLAEVIDEGIELFDHLEQYELVCLDDLQAIVGKPDWEEALFHLFNRLRDSGRRL
LIAASKSPRELPVKLPDLKSRLTMALVFQMRGLSDEDKLRALQLRASRRGLHLTDDVGHFILTRGTRSMSALFELLERLD
QASLQEKRKLTIPFLKETLGW

Sequences:

>Translated_261_residues
MCDQRHGYKLCALYTEALDGLHEPLVSMKPIQLPLSVRLRDDATFVNYYPGANAAALGYVERLCEADAGWTESLIYLWGK
DGVGRTHLLQAACLRFEQLGEPAVYLPLAEVIDEGIELFDHLEQYELVCLDDLQAIVGKPDWEEALFHLFNRLRDSGRRL
LIAASKSPRELPVKLPDLKSRLTMALVFQMRGLSDEDKLRALQLRASRRGLHLTDDVGHFILTRGTRSMSALFELLERLD
QASLQEKRKLTIPFLKETLGW
>Mature_261_residues
MCDQRHGYKLCALYTEALDGLHEPLVSMKPIQLPLSVRLRDDATFVNYYPGANAAALGYVERLCEADAGWTESLIYLWGK
DGVGRTHLLQAACLRFEQLGEPAVYLPLAEVIDEGIELFDHLEQYELVCLDDLQAIVGKPDWEEALFHLFNRLRDSGRRL
LIAASKSPRELPVKLPDLKSRLTMALVFQMRGLSDEDKLRALQLRASRRGLHLTDDVGHFILTRGTRSMSALFELLERLD
QASLQEKRKLTIPFLKETLGW

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=231, Percent_Identity=45.021645021645, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI2367267, Length=227, Percent_Identity=23.7885462555066, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 29677; Mature: 29677

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDQRHGYKLCALYTEALDGLHEPLVSMKPIQLPLSVRLRDDATFVNYYPGANAAALGYV
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHH
ERLCEADAGWTESLIYLWGKDGVGRTHLLQAACLRFEQLGEPAVYLPLAEVIDEGIELFD
HHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
HLEQYELVCLDDLQAIVGKPDWEEALFHLFNRLRDSGRRLLIAASKSPRELPVKLPDLKS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHH
RLTMALVFQMRGLSDEDKLRALQLRASRRGLHLTDDVGHFILTRGTRSMSALFELLERLD
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEECHHHHHHHHCCCCHHHHHHHHHHHHHH
QASLQEKRKLTIPFLKETLGW
HHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MCDQRHGYKLCALYTEALDGLHEPLVSMKPIQLPLSVRLRDDATFVNYYPGANAAALGYV
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHH
ERLCEADAGWTESLIYLWGKDGVGRTHLLQAACLRFEQLGEPAVYLPLAEVIDEGIELFD
HHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
HLEQYELVCLDDLQAIVGKPDWEEALFHLFNRLRDSGRRLLIAASKSPRELPVKLPDLKS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHH
RLTMALVFQMRGLSDEDKLRALQLRASRRGLHLTDDVGHFILTRGTRSMSALFELLERLD
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEECHHHHHHHHCCCCHHHHHHHHHHHHHH
QASLQEKRKLTIPFLKETLGW
HHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA