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The map label for this gene is hisQ [H]

Identifier: 66046799

GI number: 66046799

Start: 4251658

End: 4252347

Strand: Reverse

Name: hisQ [H]

Synonym: Psyr_3570

Alternate gene names: 66046799

Gene position: 4252347-4251658 (Counterclockwise)

Preceding gene: 66046800

Following gene: 66046798

Centisome position: 69.78

GC content: 60.14

Gene sequence:

>690_bases
ATGTTGAAAGGTTACGGAGCTGTCATCCTCGAAGGTGCCTGGCTGACGTTGCAGCTGGCCCTGTCGTCGATGGCTCTGGC
GATCGTTCTCGGTCTGATCGGCGTGGCGCTGAGACTGTCTCCGGTACGCTGGATCGCCTGGCTGGGCGATCTGTACAGCA
CGGTGATTCGTGGCATTCCCGATCTGGTCCTGATTCTGCTGATTTTCTACGGCGGCCAGGACCTCCTCAACCGCGTCGCC
CCGTTGCTGGGGTTTGACGACTACATCGACCTCGATCCGTTGATGGCCGGCATCTGCACGCTGGGCTTTATCTTCGGCGC
GTATCTCTCGGAAACCTTTCGCGGTGCGTTCATGGCCATTCCCAAGGGGCAGGCCGAGGCGGGCATGGCGTATGGCCTGA
GCAGTGGCAAGGTGTTCTTCCGCATTCTGGTGCCGCAGATGATTCGTCTGGCGATTCCCGGTTTCACCAACAACTGGCTG
GTGCTGACCAAGGCCACTGCGCTGATCTCCGTGGTCGGTCTGCAGGACATGATGTTCAAGGCCAAGCAGGCGGCCGATGC
CACCCGCGAGCCTTTCACCTTCTTTCTGGCGGTTGCGGCGATGTACCTGGTGATCACCAGTGTGTCGCTGCTCGCCTTGC
GTTACCTCGAAAAACGCTACTCGGTAGGCGTGAGGGCGGCTGACCTATGA

Upstream 100 bases:

>100_bases
GACTTCGATATCTTCGGCAAATAAGTCGTCGCAACGAGATGGCGCAAACAGGGTTGCCTGGCTTGCGCCATTTTTATTCC
ACGCTTGAGGACCGCACATC

Downstream 100 bases:

>100_bases
TCTTTGACTACAACGTGATCTGGGACAGTCTGCCGCTGTACTTCGGCGGGCTGCTGACCACCCTGAAGCTGCTGGCGATT
TCGCTCGCGTTCGGGCTGCT

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLKGYGAVILEGAWLTLQLALSSMALAIVLGLIGVALRLSPVRWIAWLGDLYSTVIRGIPDLVLILLIFYGGQDLLNRVA
PLLGFDDYIDLDPLMAGICTLGFIFGAYLSETFRGAFMAIPKGQAEAGMAYGLSSGKVFFRILVPQMIRLAIPGFTNNWL
VLTKATALISVVGLQDMMFKAKQAADATREPFTFFLAVAAMYLVITSVSLLALRYLEKRYSVGVRAADL

Sequences:

>Translated_229_residues
MLKGYGAVILEGAWLTLQLALSSMALAIVLGLIGVALRLSPVRWIAWLGDLYSTVIRGIPDLVLILLIFYGGQDLLNRVA
PLLGFDDYIDLDPLMAGICTLGFIFGAYLSETFRGAFMAIPKGQAEAGMAYGLSSGKVFFRILVPQMIRLAIPGFTNNWL
VLTKATALISVVGLQDMMFKAKQAADATREPFTFFLAVAAMYLVITSVSLLALRYLEKRYSVGVRAADL
>Mature_229_residues
MLKGYGAVILEGAWLTLQLALSSMALAIVLGLIGVALRLSPVRWIAWLGDLYSTVIRGIPDLVLILLIFYGGQDLLNRVA
PLLGFDDYIDLDPLMAGICTLGFIFGAYLSETFRGAFMAIPKGQAEAGMAYGLSSGKVFFRILVPQMIRLAIPGFTNNWL
VLTKATALISVVGLQDMMFKAKQAADATREPFTFFLAVAAMYLVITSVSLLALRYLEKRYSVGVRAADL

Specific function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=229, Percent_Identity=53.2751091703057, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1787087, Length=217, Percent_Identity=36.8663594470046, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788226, Length=217, Percent_Identity=30.4147465437788, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787030, Length=216, Percent_Identity=31.4814814814815, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=30.8755760368664, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786874, Length=215, Percent_Identity=26.5116279069767, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786873, Length=217, Percent_Identity=27.6497695852535, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082239, Length=140, Percent_Identity=30.7142857142857, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24908; Mature: 24908

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGYGAVILEGAWLTLQLALSSMALAIVLGLIGVALRLSPVRWIAWLGDLYSTVIRGIP
CCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLVLILLIFYGGQDLLNRVAPLLGFDDYIDLDPLMAGICTLGFIFGAYLSETFRGAFMAI
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PKGQAEAGMAYGLSSGKVFFRILVPQMIRLAIPGFTNNWLVLTKATALISVVGLQDMMFK
CCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
AKQAADATREPFTFFLAVAAMYLVITSVSLLALRYLEKRYSVGVRAADL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MLKGYGAVILEGAWLTLQLALSSMALAIVLGLIGVALRLSPVRWIAWLGDLYSTVIRGIP
CCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLVLILLIFYGGQDLLNRVAPLLGFDDYIDLDPLMAGICTLGFIFGAYLSETFRGAFMAI
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PKGQAEAGMAYGLSSGKVFFRILVPQMIRLAIPGFTNNWLVLTKATALISVVGLQDMMFK
CCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
AKQAADATREPFTFFLAVAAMYLVITSVSLLALRYLEKRYSVGVRAADL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]