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The map label for this gene is ttuB [H]

Identifier: 66046730

GI number: 66046730

Start: 4171982

End: 4173307

Strand: Direct

Name: ttuB [H]

Synonym: Psyr_3501

Alternate gene names: 66046730

Gene position: 4171982-4173307 (Clockwise)

Preceding gene: 66046729

Following gene: 66046731

Centisome position: 68.46

GC content: 61.24

Gene sequence:

>1326_bases
ATGACACCTGTTTCGACCCACGAGGTGGGCGACGCCGAAGGCAATCATGTCTACCGTCGCATCACCCTGCGCCTTATCCC
GTTTATCTTCATTTGTTACCTGTTCAATTACCTCGACCGCGTGAACGTCGGCTTTGCCAAGCTGCAGATGCTCGATGCCC
TGAGTTTCAGCGAGACGGTCTATGGCCTGGGCGCCGGTATCTTCTTCATTGGCTACGTGCTGTGTGGCCTGCCCAGCAAT
CTGGCGCTGAACCGCTTCGGGCCGCGTCGCTGGATCGGTCTGATGATGATTACCTGGGGAATCTTCTCGACCTGCCTGAT
GTTCGTCACCACGCCGGTCGAGTTCTACGTGCTGCGCTTTCTGACCGGTATGGCAGAGGCCGGTTTCTTCCCAGGCATCG
TGCTGTACCTCTCGCGCTGGTATCCAAATCAGCGTCGCGGGCGGATCATGGCACTGTTCATGTCGGCCATCCCGGTCTCC
GGCCTGCTGGGCGGCCCGTTTTCCGGACGGATTCTCAATCATTTCGCTGCGGGCCAGGGCGGCATGGCCGGCTGGCAATG
GATGTTCCTGATTCAGGGCGTGCCGACCGTGGCGCTGGGTGTGCTGGCCTTCGTTCTGCTGTGCGACAAGGTCGAGGATG
CCCGCTGGCTGACGCCCGGACAGCGTCAGCGGGTCAAGACCGATATCACCAACGATGAACTGAGCCGTCCGGTGCACGGC
AAAAGCTCGGTGGCTTCCGTGCTGAGCATGCCGTTCATATGGATCCTGGGCTTTATCTACTTCTGCATTCAAAGCGGCGT
CTACGCGATCAATTTCTGGCTGCCGTCGATCATCAAGAACCTCGGTTTCAGCGATGCACTCGTGATCGGCTGGATCAGCG
CCGTGCCGTACCTGATGGCAGGCGTGTTCATGCTGCTGGTCGGCCGCTCCGCCGACCTGCGCAATGAGCGCCGCTGGCAT
CTGGTGGTACCGATGCTGATGGGCGCGACCGGCCTGATCATCGCCGCCAATTTCGCGACGCTGCCCATCGTTGCCATCAT
CGGGCTGACTATCGCGACCATGGGTGCGCTGACCAGCCTGCCGATGTTCTGGCCATTACCGACCGCCCTGCTGAGTGCCA
GCGTCGCCGCAGGCGGGCTGGCGCTGATCAACTCGATTGGGCAGATGGCAGGCTTTCTCAGCCCTTACCTGGTGGGCTGG
ATCAAGGATCAGACCGGCTCGACTACCCTGGCGCTGTATTCACTGGCCGCGCTGACCATCGTCGGCAGTCTGGTGGCATT
GCGGGTAAGTCGGTCGTCGGCAGTCAAGGTGGCAGGGCCCGCCTGA

Upstream 100 bases:

>100_bases
AAAACCCCAAAGCGTTTTCGACACTGCCCACCTATGATCAGACGTGCGTCCAATAGCTATCTGGCTATATAAAAACAACA
AGCACAGAGGAACACCCGCC

Downstream 100 bases:

>100_bases
ATGCACTGGCCGAAGACAGCGTGATCCTGCGCAGCTGGCGTGGAGCGGGATGCGCAGATTTTTGCGCACCCAATACCCGC
ATAAAACTGATCAAGGCTCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTPVSTHEVGDAEGNHVYRRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALSFSETVYGLGAGIFFIGYVLCGLPSN
LALNRFGPRRWIGLMMITWGIFSTCLMFVTTPVEFYVLRFLTGMAEAGFFPGIVLYLSRWYPNQRRGRIMALFMSAIPVS
GLLGGPFSGRILNHFAAGQGGMAGWQWMFLIQGVPTVALGVLAFVLLCDKVEDARWLTPGQRQRVKTDITNDELSRPVHG
KSSVASVLSMPFIWILGFIYFCIQSGVYAINFWLPSIIKNLGFSDALVIGWISAVPYLMAGVFMLLVGRSADLRNERRWH
LVVPMLMGATGLIIAANFATLPIVAIIGLTIATMGALTSLPMFWPLPTALLSASVAAGGLALINSIGQMAGFLSPYLVGW
IKDQTGSTTLALYSLAALTIVGSLVALRVSRSSAVKVAGPA

Sequences:

>Translated_441_residues
MTPVSTHEVGDAEGNHVYRRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALSFSETVYGLGAGIFFIGYVLCGLPSN
LALNRFGPRRWIGLMMITWGIFSTCLMFVTTPVEFYVLRFLTGMAEAGFFPGIVLYLSRWYPNQRRGRIMALFMSAIPVS
GLLGGPFSGRILNHFAAGQGGMAGWQWMFLIQGVPTVALGVLAFVLLCDKVEDARWLTPGQRQRVKTDITNDELSRPVHG
KSSVASVLSMPFIWILGFIYFCIQSGVYAINFWLPSIIKNLGFSDALVIGWISAVPYLMAGVFMLLVGRSADLRNERRWH
LVVPMLMGATGLIIAANFATLPIVAIIGLTIATMGALTSLPMFWPLPTALLSASVAAGGLALINSIGQMAGFLSPYLVGW
IKDQTGSTTLALYSLAALTIVGSLVALRVSRSSAVKVAGPA
>Mature_440_residues
TPVSTHEVGDAEGNHVYRRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALSFSETVYGLGAGIFFIGYVLCGLPSNL
ALNRFGPRRWIGLMMITWGIFSTCLMFVTTPVEFYVLRFLTGMAEAGFFPGIVLYLSRWYPNQRRGRIMALFMSAIPVSG
LLGGPFSGRILNHFAAGQGGMAGWQWMFLIQGVPTVALGVLAFVLLCDKVEDARWLTPGQRQRVKTDITNDELSRPVHGK
SSVASVLSMPFIWILGFIYFCIQSGVYAINFWLPSIIKNLGFSDALVIGWISAVPYLMAGVFMLLVGRSADLRNERRWHL
VVPMLMGATGLIIAANFATLPIVAIIGLTIATMGALTSLPMFWPLPTALLSASVAAGGLALINSIGQMAGFLSPYLVGWI
KDQTGSTTLALYSLAALTIVGSLVALRVSRSSAVKVAGPA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=383, Percent_Identity=23.4986945169713, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082071, Length=429, Percent_Identity=35.1981351981352, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI2367379, Length=457, Percent_Identity=24.0700218818381, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789152, Length=428, Percent_Identity=24.5327102803738, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789515, Length=425, Percent_Identity=22.3529411764706, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=24.8826291079812, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17563054, Length=246, Percent_Identity=21.5447154471545, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=196, Percent_Identity=29.0816326530612, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319876, Length=218, Percent_Identity=29.3577981651376, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323032, Length=303, Percent_Identity=25.4125412541254, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321698, Length=325, Percent_Identity=24.3076923076923, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=166, Percent_Identity=25.9036144578313, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584153, Length=362, Percent_Identity=24.585635359116, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20130167, Length=417, Percent_Identity=23.5011990407674, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583789, Length=363, Percent_Identity=23.4159779614325, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48032; Mature: 47901

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCEEECCCC
>Mature Secondary Structure 
TPVSTHEVGDAEGNHVYRRITLRLIPFIFICYLFNYLDRVNVGFAKLQMLDALSFSETV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH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HHHHHHHHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]