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The map label for this gene is glnA [H]

Identifier: 66046721

GI number: 66046721

Start: 4160858

End: 4162201

Strand: Reverse

Name: glnA [H]

Synonym: Psyr_3492

Alternate gene names: 66046721

Gene position: 4162201-4160858 (Counterclockwise)

Preceding gene: 66046722

Following gene: 66046720

Centisome position: 68.3

GC content: 59.82

Gene sequence:

>1344_bases
ATGACAGGCAATGACCCCCATTCGCAGAAAGAAATGCTGATGGGCATTGATGAAGTGGAGTGTGTAACCCCGGATTTGAA
CGGTGTACCGCGCGGCAAGGTAATGACGGCTGAAGGTTTTCTCGAAGGTCGCCGTTTGCAACTGGCGCGCGGCGTGTTGC
TGCAATGCATCATGGGCGGGTATCCGCCGGCGCGCTTTTACGGCAGTGACGACGGCGATCTGGCACTGATCAGTGATCCG
CAGCAGCTCCACCGTCTGCCCTGGAGCACGTCGCCGCGAGCCTTGGCCATCTGCGATGCGCAGGACCTCGATGGCCAGCC
CTGCATGCTCTCTACCCGTAATCAGCTCAAGGCTGTTATCGCCCGTTACGTTGCGCAGGGGCTGGTGCCAGTGGTGGCCA
CCGAACTCGAGTTTTTTGTCTTCGCGCCCAATCCCGAGCCGCTTTATCCATTCGAGCCGCCGACCGGGCTGGACGGGCGA
CGCGAACAGGGGCACTCGGCATTCAGCGTCAGCTCCAACAACGGCTTGCGGACTTTTTTTGCCGAGGTGTATGCCTGCAT
GGCAGCGCTGGGGCTGCCGCGTGACACGGTGATGCACGAGATGGGTGTCAGCCAGTTCGAGATCAACCTGCTGCATGGCG
ATCCGCTGCTGCTGGCCGATCAGACTTTTCTGTTCAAGCACCTGCTCAAGGAGGTTGCGCTCAAACACGGGCTCATCGTG
GTGTGCATGGCCAAACCGCTCGCCCATACGGCGGGCAGTTCGATGCATATCCATCAGAGCGTGGTGGCAGCAGAGGGCGC
AGTGAATGTATTCAGTGATGCGCAGGGTGAGCCGAGCGACACGTTTGGTCATTTCATTGCCGGCCAGCAAGCCTGCATGG
CGGACTTCACCGCGCTGTTCGCGCCCAATGTGAATTCCTACCAGCGCCTGTGCCATCCTTATGCATCGCCCAACAACGCT
TGCTGGTCCTACGACAATCGCGCTGCCGGATTACGTATTCCGTCGAGTGCAGCGGCGGCCAGAAGGGTGGAGAATCGTCT
GCCGGGCGCTGACGCCAATCCCTATCTGGCCATCGCTGCAAGTCTGGCGGCCGGGTTGCACGGCATCGAGCAGCGACTGG
AACCGACGCCGCCGCTGCAGGGCGAACTGGAGGTGCCGGAAGAATTGTTACTGCCGTGTACCTTGCACGCTGCTCTGGAG
CGTCTGAAAAGCAGTCAGTTGGCCAAGGAACTGTTTGGTCATGAATTCATCGAAGGCTACATTGCGTCGAAGGCCCTGGA
ACTGACCAGTTTTTTCGACGAGATAACCCCCTGGGAACGGCGCGTGCTGGCTGCTCAGGTTTAA

Upstream 100 bases:

>100_bases
CACGCTTAGCGGCAGGCCGGCAGCCTGGAGCGCGGTGCTTGAAGATTGCAGTCTGAAGGTTGAAGCTTGGCGTCTGCTGC
TCAACTAAAAGGACTGACCC

Downstream 100 bases:

>100_bases
GAATCGCAGTGTCGGGCTCGCCCAGTCGGGCGACTCCCTATTTTTGGAAAGTTGATGCGCCAAATCTGGAAGTCCTTTCG
AGCGCTTTATTTTGCCTCGT

Product: glutamate--ammonia ligase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTGNDPHSQKEMLMGIDEVECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGGYPPARFYGSDDGDLALISDP
QQLHRLPWSTSPRALAICDAQDLDGQPCMLSTRNQLKAVIARYVAQGLVPVVATELEFFVFAPNPEPLYPFEPPTGLDGR
REQGHSAFSVSSNNGLRTFFAEVYACMAALGLPRDTVMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLIV
VCMAKPLAHTAGSSMHIHQSVVAAEGAVNVFSDAQGEPSDTFGHFIAGQQACMADFTALFAPNVNSYQRLCHPYASPNNA
CWSYDNRAAGLRIPSSAAAARRVENRLPGADANPYLAIAASLAAGLHGIEQRLEPTPPLQGELEVPEELLLPCTLHAALE
RLKSSQLAKELFGHEFIEGYIASKALELTSFFDEITPWERRVLAAQV

Sequences:

>Translated_447_residues
MTGNDPHSQKEMLMGIDEVECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGGYPPARFYGSDDGDLALISDP
QQLHRLPWSTSPRALAICDAQDLDGQPCMLSTRNQLKAVIARYVAQGLVPVVATELEFFVFAPNPEPLYPFEPPTGLDGR
REQGHSAFSVSSNNGLRTFFAEVYACMAALGLPRDTVMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLIV
VCMAKPLAHTAGSSMHIHQSVVAAEGAVNVFSDAQGEPSDTFGHFIAGQQACMADFTALFAPNVNSYQRLCHPYASPNNA
CWSYDNRAAGLRIPSSAAAARRVENRLPGADANPYLAIAASLAAGLHGIEQRLEPTPPLQGELEVPEELLLPCTLHAALE
RLKSSQLAKELFGHEFIEGYIASKALELTSFFDEITPWERRVLAAQV
>Mature_446_residues
TGNDPHSQKEMLMGIDEVECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGGYPPARFYGSDDGDLALISDPQ
QLHRLPWSTSPRALAICDAQDLDGQPCMLSTRNQLKAVIARYVAQGLVPVVATELEFFVFAPNPEPLYPFEPPTGLDGRR
EQGHSAFSVSSNNGLRTFFAEVYACMAALGLPRDTVMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLIVV
CMAKPLAHTAGSSMHIHQSVVAAEGAVNVFSDAQGEPSDTFGHFIAGQQACMADFTALFAPNVNSYQRLCHPYASPNNAC
WSYDNRAAGLRIPSSAAAARRVENRLPGADANPYLAIAASLAAGLHGIEQRLEPTPPLQGELEVPEELLLPCTLHAALER
LKSSQLAKELFGHEFIEGYIASKALELTSFFDEITPWERRVLAAQV

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=426, Percent_Identity=25.5868544600939, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI87081870, Length=431, Percent_Identity=33.4106728538283, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1790301, Length=259, Percent_Identity=32.4324324324324, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 48639; Mature: 48508

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNDPHSQKEMLMGIDEVECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGG
CCCCCCCHHHHHHHCCCHHEEECCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCC
YPPARFYGSDDGDLALISDPQQLHRLPWSTSPRALAICDAQDLDGQPCMLSTRNQLKAVI
CCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
ARYVAQGLVPVVATELEFFVFAPNPEPLYPFEPPTGLDGRREQGHSAFSVSSNNGLRTFF
HHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHCCCCEEEECCCCCHHHHH
AEVYACMAALGLPRDTVMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLIV
HHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCEEEEECHHHHHHHHHHHHHHHCCEEE
VCMAKPLAHTAGSSMHIHQSVVAAEGAVNVFSDAQGEPSDTFGHFIAGQQACMADFTALF
EEECCHHHHHCCCCEEHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHH
APNVNSYQRLCHPYASPNNACWSYDNRAAGLRIPSSAAAARRVENRLPGADANPYLAIAA
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
SLAAGLHGIEQRLEPTPPLQGELEVPEELLLPCTLHAALERLKSSQLAKELFGHEFIEGY
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASKALELTSFFDEITPWERRVLAAQV
HHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
TGNDPHSQKEMLMGIDEVECVTPDLNGVPRGKVMTAEGFLEGRRLQLARGVLLQCIMGG
CCCCCCHHHHHHHCCCHHEEECCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHCC
YPPARFYGSDDGDLALISDPQQLHRLPWSTSPRALAICDAQDLDGQPCMLSTRNQLKAVI
CCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
ARYVAQGLVPVVATELEFFVFAPNPEPLYPFEPPTGLDGRREQGHSAFSVSSNNGLRTFF
HHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHCCCCEEEECCCCCHHHHH
AEVYACMAALGLPRDTVMHEMGVSQFEINLLHGDPLLLADQTFLFKHLLKEVALKHGLIV
HHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCEEEEECHHHHHHHHHHHHHHHCCEEE
VCMAKPLAHTAGSSMHIHQSVVAAEGAVNVFSDAQGEPSDTFGHFIAGQQACMADFTALF
EEECCHHHHHCCCCEEHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHH
APNVNSYQRLCHPYASPNNACWSYDNRAAGLRIPSSAAAARRVENRLPGADANPYLAIAA
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
SLAAGLHGIEQRLEPTPPLQGELEVPEELLLPCTLHAALERLKSSQLAKELFGHEFIEGY
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASKALELTSFFDEITPWERRVLAAQV
HHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]