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The map label for this gene is ycgR [H]

Identifier: 66046719

GI number: 66046719

Start: 4158573

End: 4159319

Strand: Direct

Name: ycgR [H]

Synonym: Psyr_3490

Alternate gene names: 66046719

Gene position: 4158573-4159319 (Clockwise)

Preceding gene: 66046718

Following gene: 66046723

Centisome position: 68.24

GC content: 57.97

Gene sequence:

>747_bases
GTGAATGGCTCAAGCGCGGACGATGCTCCGCAGCCCCCGAAGGTTCTCAATACACCTTTGGAAATTGCCGCTAACCTGCG
GCTGCTACTCGAGAGTCATGATCCTCTGATCATTACCTTTCACGAGCGTCCCCAGCGCTTTCAGAGTTATCTGCTTGAAG
TCGACCGTGACAACAACGTCATGGCCCTCGACGAAATGATCCCCCGCGATGGCGAACGCTTTCTGAGCAACGGCGAATCC
TTCCGTGTCGAAGGCTTTCATGATGGCGTGCGGATTGCCTGGGAAAGTACTGCGCAGATGGACATCCTCAGCACCGACGG
TCAACGCATGTACCGCGGCCCGATGCCTGAGGAAGTGGTTTATCACCAGCGCCGCAACGCCTTCCGGGCCGCGCTGAAGC
TGGCGCAACTGGTCGACGTCGAAATCGGCGGTGACCGCCTGAAATTCACGCTGGCCGGCAAGCTGCTGGATATTTCTGCC
ACCGGCTGCAAGTTGCGCTTCGAGGGCGACGTGTCCGATCGCATGCAATTGGGCCAGGTATACGAGCGTTTCGTTGCCAA
GCTGCCTTTCGGCGCCATGACAGCACCTGTCGAGTTGCGCCACCTGCATTTCGAAGAACGATTCAACACCACCTTTGCCG
GCGTGCGCTTCCACAACATGAGTGGGCTGGTGCAGCGTCAGGTCGAACGTTTCGTCTATCAGTTACAGCGCGAAGCACGG
CGCTTCGACAAAGACGACGACTTCTGA

Upstream 100 bases:

>100_bases
CCTCTGAGCCAGGCGTAACTTCCTGTATCAAGGTTTCGTGCATAGTGGCAGAATGCCTGCTGTTGCGTTGCCGTAGTATT
TTGCCTGGAGATTCAAGAAC

Downstream 100 bases:

>100_bases
CGCTCACCTGAATCCCCCGGCGATTGCGGCATTGCTGCCGCAATCGTGCACTGCCCTACCCCTCAGGCCTTCCAGGTCTC
GCTTTCACGCTCGCGTTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNGSSADDAPQPPKVLNTPLEIAANLRLLLESHDPLIITFHERPQRFQSYLLEVDRDNNVMALDEMIPRDGERFLSNGES
FRVEGFHDGVRIAWESTAQMDILSTDGQRMYRGPMPEEVVYHQRRNAFRAALKLAQLVDVEIGGDRLKFTLAGKLLDISA
TGCKLRFEGDVSDRMQLGQVYERFVAKLPFGAMTAPVELRHLHFEERFNTTFAGVRFHNMSGLVQRQVERFVYQLQREAR
RFDKDDDF

Sequences:

>Translated_248_residues
MNGSSADDAPQPPKVLNTPLEIAANLRLLLESHDPLIITFHERPQRFQSYLLEVDRDNNVMALDEMIPRDGERFLSNGES
FRVEGFHDGVRIAWESTAQMDILSTDGQRMYRGPMPEEVVYHQRRNAFRAALKLAQLVDVEIGGDRLKFTLAGKLLDISA
TGCKLRFEGDVSDRMQLGQVYERFVAKLPFGAMTAPVELRHLHFEERFNTTFAGVRFHNMSGLVQRQVERFVYQLQREAR
RFDKDDDF
>Mature_248_residues
MNGSSADDAPQPPKVLNTPLEIAANLRLLLESHDPLIITFHERPQRFQSYLLEVDRDNNVMALDEMIPRDGERFLSNGES
FRVEGFHDGVRIAWESTAQMDILSTDGQRMYRGPMPEEVVYHQRRNAFRAALKLAQLVDVEIGGDRLKFTLAGKLLDISA
TGCKLRFEGDVSDRMQLGQVYERFVAKLPFGAMTAPVELRHLHFEERFNTTFAGVRFHNMSGLVQRQVERFVYQLQREAR
RFDKDDDF

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility. Binds c-di-GMP with a dissociation constant of 165 nM [H]

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009875
- InterPro:   IPR012349
- InterPro:   IPR009926 [H]

Pfam domain/function: PF07238 PilZ; PF07317 YcgR [H]

EC number: NA

Molecular weight: Translated: 28562; Mature: 28562

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSSADDAPQPPKVLNTPLEIAANLRLLLESHDPLIITFHERPQRFQSYLLEVDRDNNV
CCCCCCCCCCCCHHHHCCHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHHHEECCCCCE
MALDEMIPRDGERFLSNGESFRVEGFHDGVRIAWESTAQMDILSTDGQRMYRGPMPEEVV
EEHHHHCCCCCHHHHCCCCEEEEECCCCCEEEEECCCCEEEEEECCCCEEECCCCCHHHH
YHQRRNAFRAALKLAQLVDVEIGGDRLKFTLAGKLLDISATGCKLRFEGDVSDRMQLGQV
HHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECEEEEEECCCEEEEECCCCHHHHHHHHH
YERFVAKLPFGAMTAPVELRHLHFEERFNTTFAGVRFHNMSGLVQRQVERFVYQLQREAR
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHH
RFDKDDDF
CCCCCCCC
>Mature Secondary Structure
MNGSSADDAPQPPKVLNTPLEIAANLRLLLESHDPLIITFHERPQRFQSYLLEVDRDNNV
CCCCCCCCCCCCHHHHCCHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHHHEECCCCCE
MALDEMIPRDGERFLSNGESFRVEGFHDGVRIAWESTAQMDILSTDGQRMYRGPMPEEVV
EEHHHHCCCCCHHHHCCCCEEEEECCCCCEEEEECCCCEEEEEECCCCEEECCCCCHHHH
YHQRRNAFRAALKLAQLVDVEIGGDRLKFTLAGKLLDISATGCKLRFEGDVSDRMQLGQV
HHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECEEEEEECCCEEEEECCCCHHHHHHHHH
YERFVAKLPFGAMTAPVELRHLHFEERFNTTFAGVRFHNMSGLVQRQVERFVYQLQREAR
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHH
RFDKDDDF
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]