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The map label for this gene is gnuT [H]

Identifier: 66046567

GI number: 66046567

Start: 3993358

End: 3994710

Strand: Direct

Name: gnuT [H]

Synonym: Psyr_3338

Alternate gene names: 66046567

Gene position: 3993358-3994710 (Clockwise)

Preceding gene: 66046566

Following gene: 66046568

Centisome position: 65.53

GC content: 60.46

Gene sequence:

>1353_bases
ATGTTCGGTATGACCCATGAGACGTTCCTGCTCGTCGATGCGTTGGTGACCATCGTCGGCCTGGTGCTGCTGATCACCAC
CTTCAAGGTGCACCCTTTCGTCGCGTTGACCCTGGCGGCAGGCTTTCTTGGCCTGACCTCGGGAATGCCGGTGGAAAAAG
TCATGAAATCCTTCCAGGACGGCTTCGGCGGCGTACTGGGCTTCGTTGGTATCATCCTCGGCCTGGGCACCATGCTCGGC
AAGCTGATGGCCGACTCGGGCGGCGCGGACCAGATTGCGCAAACGCTGATACGCACCTTCGGCAAACAGAAAGTGCACTG
GGCAATGATGTTCTCTGCCTTTCTGGTGGGCATCCCGCTGTTCTTCGAGATCGGTTTTGTCCTGCTGATCCCGCTGGTGT
TCATCGTCGCGCGGCGCACCGGCGTGCCCATCGTCAAGATCGGCATTCCGCTGCTGGCAGGCCTGTCGGCCGTACACGGT
CTGGTTCCTCCGCATCCAGGTCCGTTGCTGGCCATCGGCATCTTCGGGGCTGACATCGGCAAAACCATTTTCTACGGACT
GATCGTTGCGCTGCCGACGGCCATCATCGCTGGCCCGATCTTCGGTAACTGGATTTCCAAAAGCATCCCCGGCACACCGT
CCAAGGAACTGATGGATCAGATCGCCAAGGAGTCGAGCACTGAAAACCTGCCAGGCTTCGGCATCACGCTGGTGACCATC
CTGCTGCCGGTCTTCCTGATGCTGCTCAAGACCTTTGCCGACGTGGTGTTGCCGGAAAACAACATGTTCCGCATCTGGAT
GGACCTGATCGGTCACCCGATCACCGCCCTGCTTGCCGCGCTGTTGCTGGCGTTCTACACCTTTGGTGCCGCGCGTGGTT
TCGACCGCAGCAAGATCATGAAGCTGCTGGACCAGAGTCTGGCCCCGGTGGCGGCAATCGTGCTGATTGTCGGCGCAGGC
GGTGGCTTCAAGCAGATGCTGGTCGCCAGTGGCGTAGGTGACGTGATCGGGCACATGGCCGTGCAGGCGCAGATCAACCC
GATCATGCTGGCCTGGCTGGTTGCGGCGGTCATCCGCGTCGCAACAGGTTCGGCGACGGTGGCAACCATTACCGGTGCTG
GCATCGTAGCGCCGGTGGTCGGCCTGATTCCAGGGGTCAATCGCGAGCTGCTGGTGCTGGCAACCGGCGCCGGCTCGTTG
ATCCTGTCGCACGTCAATGACGCCGGGTTCTGGCTGGTGAAGCAGTACTTCAACATGACCGTTGCCGAGACCTTCAAGAC
CTGGACGGTGATGGAGACCATCCTCTCGGTCGTCGGCCTGATCTTCATCATGCTGTTGTCAATGGCGGTGTAA

Upstream 100 bases:

>100_bases
TGAGCATTCCGAGCCTGTTTTTAACGCAGCATCACCGAGCGCAGCCACTTTACGTACAGAGCCTAACAGTTCCTTAAAAC
AATAAACCGGAGAGACACCC

Downstream 100 bases:

>100_bases
ACCCCGGCCAAGCCTTCGCGGGAGCTGAAGCCCGCGAGGGCCTGGCCCCGCCTCACACCTGTGCATCACCCCACTCCAGT
CCCCCCGCAATACCCCGCAT

Product: gluconate transporter

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MFGMTHETFLLVDALVTIVGLVLLITTFKVHPFVALTLAAGFLGLTSGMPVEKVMKSFQDGFGGVLGFVGIILGLGTMLG
KLMADSGGADQIAQTLIRTFGKQKVHWAMMFSAFLVGIPLFFEIGFVLLIPLVFIVARRTGVPIVKIGIPLLAGLSAVHG
LVPPHPGPLLAIGIFGADIGKTIFYGLIVALPTAIIAGPIFGNWISKSIPGTPSKELMDQIAKESSTENLPGFGITLVTI
LLPVFLMLLKTFADVVLPENNMFRIWMDLIGHPITALLAALLLAFYTFGAARGFDRSKIMKLLDQSLAPVAAIVLIVGAG
GGFKQMLVASGVGDVIGHMAVQAQINPIMLAWLVAAVIRVATGSATVATITGAGIVAPVVGLIPGVNRELLVLATGAGSL
ILSHVNDAGFWLVKQYFNMTVAETFKTWTVMETILSVVGLIFIMLLSMAV

Sequences:

>Translated_450_residues
MFGMTHETFLLVDALVTIVGLVLLITTFKVHPFVALTLAAGFLGLTSGMPVEKVMKSFQDGFGGVLGFVGIILGLGTMLG
KLMADSGGADQIAQTLIRTFGKQKVHWAMMFSAFLVGIPLFFEIGFVLLIPLVFIVARRTGVPIVKIGIPLLAGLSAVHG
LVPPHPGPLLAIGIFGADIGKTIFYGLIVALPTAIIAGPIFGNWISKSIPGTPSKELMDQIAKESSTENLPGFGITLVTI
LLPVFLMLLKTFADVVLPENNMFRIWMDLIGHPITALLAALLLAFYTFGAARGFDRSKIMKLLDQSLAPVAAIVLIVGAG
GGFKQMLVASGVGDVIGHMAVQAQINPIMLAWLVAAVIRVATGSATVATITGAGIVAPVVGLIPGVNRELLVLATGAGSL
ILSHVNDAGFWLVKQYFNMTVAETFKTWTVMETILSVVGLIFIMLLSMAV
>Mature_450_residues
MFGMTHETFLLVDALVTIVGLVLLITTFKVHPFVALTLAAGFLGLTSGMPVEKVMKSFQDGFGGVLGFVGIILGLGTMLG
KLMADSGGADQIAQTLIRTFGKQKVHWAMMFSAFLVGIPLFFEIGFVLLIPLVFIVARRTGVPIVKIGIPLLAGLSAVHG
LVPPHPGPLLAIGIFGADIGKTIFYGLIVALPTAIIAGPIFGNWISKSIPGTPSKELMDQIAKESSTENLPGFGITLVTI
LLPVFLMLLKTFADVVLPENNMFRIWMDLIGHPITALLAALLLAFYTFGAARGFDRSKIMKLLDQSLAPVAAIVLIVGAG
GGFKQMLVASGVGDVIGHMAVQAQINPIMLAWLVAAVIRVATGSATVATITGAGIVAPVVGLIPGVNRELLVLATGAGSL
ILSHVNDAGFWLVKQYFNMTVAETFKTWTVMETILSVVGLIFIMLLSMAV

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=444, Percent_Identity=46.3963963963964, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1790716, Length=421, Percent_Identity=43.9429928741093, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI2367370, Length=427, Percent_Identity=43.0913348946136, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1790776, Length=436, Percent_Identity=38.0733944954128, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1788707, Length=450, Percent_Identity=39.7777777777778, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI48994939, Length=445, Percent_Identity=39.5505617977528, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789097, Length=443, Percent_Identity=35.2144469525959, Blast_Score=243, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47443; Mature: 47443

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]