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The map label for this gene is ybhO [H]

Identifier: 66046506

GI number: 66046506

Start: 3924848

End: 3926098

Strand: Reverse

Name: ybhO [H]

Synonym: Psyr_3277

Alternate gene names: 66046506

Gene position: 3926098-3924848 (Counterclockwise)

Preceding gene: 66046507

Following gene: 66046505

Centisome position: 64.43

GC content: 58.59

Gene sequence:

>1251_bases
ATGAGCAATACGACAGGGCAGTGGCGCGACGGCAACTCGGTAGAGTTGCTGATCAATGGCGAGGATTTCTACGCCCGCGT
ATTCGAATGCATACGTGCCGCGCGCAAAGAAGTGCTGATCGAGACCTTCATCATTTTTGAAGACCGGATCGGCGAGAGCC
TGCAACAGGCGTTGCTCGAAGCCGCCGCGAATGGCGCGAAGGTGGTCGTCACGGTGGATGACTATGGCACCTCGGACCTG
AGTTCGACGTTTGTCAAAACCATGATCGACGCCGGTATCCAGATTCAGCTGTTCGATCCGCGCCCGCGGTTCATGGGCAT
GCGCACCAATCTGTTTCGCCGTCTGCACCGTAAGGTGGTGGTGATCGATGGCGAACTGGGCTTTATCGGCGGCATCAACT
ACAGCGTTGATCATATGACCGACACCGGTCTGACGGCCAAACAGGACTACGCCGTTCTGGTGCGCGGGCCGATTGTTGGC
GACATTCACCACAGCGCGTTGAATATGCTCAGCAAGGTCGTTCGTGACAAATTGCCGCCCATTGCACTCAAGCTGGACCG
CGCCGGTGACGCCAGCATGCTGCTCGCCGAGCGCGACAATGACGAGCACAGCACCGATATCGAAGAGCAGTACCTGGAGG
CGATTCGCGCTGCTAAGCAACGCATCACCCTGGCCAATGCGTATTTTTACCCCAGCTACCGCTTTCTGCGTGAGCTGCGC
AACGCCTCACGGCGGGGCGTCAAGGTCACCCTGATCCTGCAAGGCCAGCCCGACATGCCGTTCGTGCGGGTCTGCTCGCG
ACTGACCTACACCTACCTGCTGCGCGATGGCGTGGCCATTCACGAATACAAGCAACGTGCATTGCACGGCAAGGTCGCGC
TGATCGACCAGGACTGGTCCACCGTGGGTTCCAGCAATCTCGACCCGCTGAGCCTGGCGCTGAACCTGGAAGCCAACCTG
TTCATTCGTGATCGCACCCTCAATGAGCATCTGCAAAATCATCTGATGGAGCTTGCCGCGGCGCACAGCAAACAGATGAG
CCTCAAGGGTGCGGCGCGTGGCCAGTGGTGGCGTGCGCCGATGATCGTCTTGAGTTTCTTTTTCCTGCGCCGTTTCCCGG
CCATTGCCGGTTTGTTCCCGGTTCACGGTGTGCGCCTCAAGCCTTTGCGTGCCGGTGATGTAGTGCCCGAAGCGAAAGTG
ATCGAACAGCAGCAGAACAACCATCCGATGGATCAGGAGAAAACCCTATGA

Upstream 100 bases:

>100_bases
TCTATGTCCGCAATGCGACCTCGCACCGGCCGAAAGTGTTGTCCAGCCGACCGTGGTCGCACCTTTCCGATCATGCACCG
CTGGCGGTGGAGTTGACCTT

Downstream 100 bases:

>100_bases
CCCAAGCCACGCAGGCAGCGCCGCACAGTGCGCAGGGAACCAGGTGGAAGTGGGCAAAGCGGGCGTTCAATCTGTTTTTC
TTCATCGCCGTCCCGGTTCT

Product: cardiolipin synthase 2

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSNTTGQWRDGNSVELLINGEDFYARVFECIRAARKEVLIETFIIFEDRIGESLQQALLEAAANGAKVVVTVDDYGTSDL
SSTFVKTMIDAGIQIQLFDPRPRFMGMRTNLFRRLHRKVVVIDGELGFIGGINYSVDHMTDTGLTAKQDYAVLVRGPIVG
DIHHSALNMLSKVVRDKLPPIALKLDRAGDASMLLAERDNDEHSTDIEEQYLEAIRAAKQRITLANAYFYPSYRFLRELR
NASRRGVKVTLILQGQPDMPFVRVCSRLTYTYLLRDGVAIHEYKQRALHGKVALIDQDWSTVGSSNLDPLSLALNLEANL
FIRDRTLNEHLQNHLMELAAAHSKQMSLKGAARGQWWRAPMIVLSFFFLRRFPAIAGLFPVHGVRLKPLRAGDVVPEAKV
IEQQQNNHPMDQEKTL

Sequences:

>Translated_416_residues
MSNTTGQWRDGNSVELLINGEDFYARVFECIRAARKEVLIETFIIFEDRIGESLQQALLEAAANGAKVVVTVDDYGTSDL
SSTFVKTMIDAGIQIQLFDPRPRFMGMRTNLFRRLHRKVVVIDGELGFIGGINYSVDHMTDTGLTAKQDYAVLVRGPIVG
DIHHSALNMLSKVVRDKLPPIALKLDRAGDASMLLAERDNDEHSTDIEEQYLEAIRAAKQRITLANAYFYPSYRFLRELR
NASRRGVKVTLILQGQPDMPFVRVCSRLTYTYLLRDGVAIHEYKQRALHGKVALIDQDWSTVGSSNLDPLSLALNLEANL
FIRDRTLNEHLQNHLMELAAAHSKQMSLKGAARGQWWRAPMIVLSFFFLRRFPAIAGLFPVHGVRLKPLRAGDVVPEAKV
IEQQQNNHPMDQEKTL
>Mature_415_residues
SNTTGQWRDGNSVELLINGEDFYARVFECIRAARKEVLIETFIIFEDRIGESLQQALLEAAANGAKVVVTVDDYGTSDLS
STFVKTMIDAGIQIQLFDPRPRFMGMRTNLFRRLHRKVVVIDGELGFIGGINYSVDHMTDTGLTAKQDYAVLVRGPIVGD
IHHSALNMLSKVVRDKLPPIALKLDRAGDASMLLAERDNDEHSTDIEEQYLEAIRAAKQRITLANAYFYPSYRFLRELRN
ASRRGVKVTLILQGQPDMPFVRVCSRLTYTYLLRDGVAIHEYKQRALHGKVALIDQDWSTVGSSNLDPLSLALNLEANLF
IRDRTLNEHLQNHLMELAAAHSKQMSLKGAARGQWWRAPMIVLSFFFLRRFPAIAGLFPVHGVRLKPLRAGDVVPEAKVI
EQQQNNHPMDQEKTL

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=383, Percent_Identity=50.1305483028721, Blast_Score=383, Evalue=1e-107,
Organism=Escherichia coli, GI1787502, Length=340, Percent_Identity=26.4705882352941, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 47000; Mature: 46869

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTTGQWRDGNSVELLINGEDFYARVFECIRAARKEVLIETFIIFEDRIGESLQQALLE
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAANGAKVVVTVDDYGTSDLSSTFVKTMIDAGIQIQLFDPRPRFMGMRTNLFRRLHRKVV
HHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHCHHHHHHHHHCCEEE
VIDGELGFIGGINYSVDHMTDTGLTAKQDYAVLVRGPIVGDIHHSALNMLSKVVRDKLPP
EEECCCCEEECCCCEECCCCCCCCCCCCCCEEEEECCEECHHHHHHHHHHHHHHHHCCCC
IALKLDRAGDASMLLAERDNDEHSTDIEEQYLEAIRAAKQRITLANAYFYPSYRFLRELR
EEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHH
NASRRGVKVTLILQGQPDMPFVRVCSRLTYTYLLRDGVAIHEYKQRALHGKVALIDQDWS
HHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCHH
TVGSSNLDPLSLALNLEANLFIRDRTLNEHLQNHLMELAAAHSKQMSLKGAARGQWWRAP
HCCCCCCCCEEEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MIVLSFFFLRRFPAIAGLFPVHGVRLKPLRAGDVVPEAKVIEQQQNNHPMDQEKTL
HHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SNTTGQWRDGNSVELLINGEDFYARVFECIRAARKEVLIETFIIFEDRIGESLQQALLE
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAANGAKVVVTVDDYGTSDLSSTFVKTMIDAGIQIQLFDPRPRFMGMRTNLFRRLHRKVV
HHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHCHHHHHHHHHCCEEE
VIDGELGFIGGINYSVDHMTDTGLTAKQDYAVLVRGPIVGDIHHSALNMLSKVVRDKLPP
EEECCCCEEECCCCEECCCCCCCCCCCCCCEEEEECCEECHHHHHHHHHHHHHHHHCCCC
IALKLDRAGDASMLLAERDNDEHSTDIEEQYLEAIRAAKQRITLANAYFYPSYRFLRELR
EEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHH
NASRRGVKVTLILQGQPDMPFVRVCSRLTYTYLLRDGVAIHEYKQRALHGKVALIDQDWS
HHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCHH
TVGSSNLDPLSLALNLEANLFIRDRTLNEHLQNHLMELAAAHSKQMSLKGAARGQWWRAP
HCCCCCCCCEEEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
MIVLSFFFLRRFPAIAGLFPVHGVRLKPLRAGDVVPEAKVIEQQQNNHPMDQEKTL
HHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]