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The map label for this gene is epsA [H]

Identifier: 66046461

GI number: 66046461

Start: 3871564

End: 3872652

Strand: Direct

Name: epsA [H]

Synonym: Psyr_3232

Alternate gene names: 66046461

Gene position: 3871564-3872652 (Clockwise)

Preceding gene: 66046460

Following gene: 66046462

Centisome position: 63.53

GC content: 62.17

Gene sequence:

>1089_bases
ATGAATCGAAGCATTACTGCGTTACTGCTGGTCAGCCTGGCGCTGCAAGGCTGTGCATTCGCGCCGGGGCAACATATGAC
GCCGGATGACGTCACCCTCGACACGCCGGACGAACCCCGGGCACAGTTGATCGAGGTCACCCCGAAAACCCTGCAGCAAC
AGCAATTGCGCGCCACCGCCGAGGCCAAAGCCCTGCCGCAGGTGCTGCTCGACTACAGGACTCCGGAATACGTGATCGGT
GCTGGCGATACCTTGCTGGTCACCGTGTTCGAACACCCCGAACTGACCGCGCCGGGCTCACAGGACCAGCTGGATGCCAA
CACCCGGGAAGTGCTCAATGACGGCACGCTCTACTTCCCCTATGTAGGCAGAATCCGCGCGAGTGGCAGAACGGTCAGCG
AGGTTCGTGAGCAGTTACGCATGGGCCTGGCGCCGCAATACACCGAGGTCAAGGTCGACGTCAAAGTGCTGCGCTACAAC
AGCCAGCGAATACTGCTGTCCGGCTCTTTCAAGGTTCCCGGCCCGCAACCGATTACCAATATTCCGTTGAGCCTGGTGCA
GGCGGTGAGTGTCGCCGGTGTCGACCTGACCGATGCCAACCTGGCCGGGCTGACCCTGCGCCGCGAGGGCAAGGACTACC
TGATCGACATCGACTCGCTGAATCGCCGCGATTCGCAACTGAGCCGGATCTTCCTGAAGGACGGCGATTACCTGCACCTC
AACAGCAACTCGCGAAACAAGATCTACGTGCTGGGCGAGGTCCGTAACCCTCAGGTGATCTCGTTCGGCACCACGCGCCT
GACCCTGCTCGAGGCGTTGGGAAACTCCGGCGGCCTCAGCCCGGACAGCGCAGACGGCGATGCGGTGTACGTCATACGTG
GTGCGGAAGACTTCGCCCAGGCGCCCTCCACCGTCTACCACCTCAATGCCAAAAAGCCCACCGCCTACCTGCTGGCGGGG
CAGTTCGAGCTCAAGGCACAGGATGTGGTGTTCGTCGGCCCTGCCGATATCACCCGCTGGAGCCGCTTCATCAGCCAGCT
GCTCGGCTCGGCCAGTGTGATACAGACCGGTGCGGCCTTTCGCAACTGA

Upstream 100 bases:

>100_bases
TCAACAAGAACGCCTTCTGATGCCTGCGCTGACCTGAGCACCCACCGAACACCCTCGGTACGCAACACGAAAGGAGCAAT
GCCATGAAAGGAAAAACGTC

Downstream 100 bases:

>100_bases
CCCGGGCGGCCATTCGCCGATCTCCCTGCACGCAGTTGTGCAGGGATTTTTTTTGCCCGTCGCACCGCGTCAGACTGTTG
CCAGAGCAACAGCTGTTCAA

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNRSITALLLVSLALQGCAFAPGQHMTPDDVTLDTPDEPRAQLIEVTPKTLQQQQLRATAEAKALPQVLLDYRTPEYVIG
AGDTLLVTVFEHPELTAPGSQDQLDANTREVLNDGTLYFPYVGRIRASGRTVSEVREQLRMGLAPQYTEVKVDVKVLRYN
SQRILLSGSFKVPGPQPITNIPLSLVQAVSVAGVDLTDANLAGLTLRREGKDYLIDIDSLNRRDSQLSRIFLKDGDYLHL
NSNSRNKIYVLGEVRNPQVISFGTTRLTLLEALGNSGGLSPDSADGDAVYVIRGAEDFAQAPSTVYHLNAKKPTAYLLAG
QFELKAQDVVFVGPADITRWSRFISQLLGSASVIQTGAAFRN

Sequences:

>Translated_362_residues
MNRSITALLLVSLALQGCAFAPGQHMTPDDVTLDTPDEPRAQLIEVTPKTLQQQQLRATAEAKALPQVLLDYRTPEYVIG
AGDTLLVTVFEHPELTAPGSQDQLDANTREVLNDGTLYFPYVGRIRASGRTVSEVREQLRMGLAPQYTEVKVDVKVLRYN
SQRILLSGSFKVPGPQPITNIPLSLVQAVSVAGVDLTDANLAGLTLRREGKDYLIDIDSLNRRDSQLSRIFLKDGDYLHL
NSNSRNKIYVLGEVRNPQVISFGTTRLTLLEALGNSGGLSPDSADGDAVYVIRGAEDFAQAPSTVYHLNAKKPTAYLLAG
QFELKAQDVVFVGPADITRWSRFISQLLGSASVIQTGAAFRN
>Mature_362_residues
MNRSITALLLVSLALQGCAFAPGQHMTPDDVTLDTPDEPRAQLIEVTPKTLQQQQLRATAEAKALPQVLLDYRTPEYVIG
AGDTLLVTVFEHPELTAPGSQDQLDANTREVLNDGTLYFPYVGRIRASGRTVSEVREQLRMGLAPQYTEVKVDVKVLRYN
SQRILLSGSFKVPGPQPITNIPLSLVQAVSVAGVDLTDANLAGLTLRREGKDYLIDIDSLNRRDSQLSRIFLKDGDYLHL
NSNSRNKIYVLGEVRNPQVISFGTTRLTLLEALGNSGGLSPDSADGDAVYVIRGAEDFAQAPSTVYHLNAKKPTAYLLAG
QFELKAQDVVFVGPADITRWSRFISQLLGSASVIQTGAAFRN

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=356, Percent_Identity=33.4269662921348, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788376, Length=361, Percent_Identity=31.8559556786704, Blast_Score=178, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 39521; Mature: 39521

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSITALLLVSLALQGCAFAPGQHMTPDDVTLDTPDEPRAQLIEVTPKTLQQQQLRATA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHEEECCHHHHHHHHHHHHH
EAKALPQVLLDYRTPEYVIGAGDTLLVTVFEHPELTAPGSQDQLDANTREVLNDGTLYFP
HHHHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCEEEC
YVGRIRASGRTVSEVREQLRMGLAPQYTEVKVDVKVLRYNSQRILLSGSFKVPGPQPITN
EEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCCCCCC
IPLSLVQAVSVAGVDLTDANLAGLTLRREGKDYLIDIDSLNRRDSQLSRIFLKDGDYLHL
CCHHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCHHHEEEEECCCEEEE
NSNSRNKIYVLGEVRNPQVISFGTTRLTLLEALGNSGGLSPDSADGDAVYVIRGAEDFAQ
CCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHH
APSTVYHLNAKKPTAYLLAGQFELKAQDVVFVGPADITRWSRFISQLLGSASVIQTGAAF
CCCEEEEEECCCCEEEEEEEEEEEEECCEEEECCHHHHHHHHHHHHHHCCHHHHHCCHHC
RN
CC
>Mature Secondary Structure
MNRSITALLLVSLALQGCAFAPGQHMTPDDVTLDTPDEPRAQLIEVTPKTLQQQQLRATA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHEEECCHHHHHHHHHHHHH
EAKALPQVLLDYRTPEYVIGAGDTLLVTVFEHPELTAPGSQDQLDANTREVLNDGTLYFP
HHHHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCEEEC
YVGRIRASGRTVSEVREQLRMGLAPQYTEVKVDVKVLRYNSQRILLSGSFKVPGPQPITN
EEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCCCCCC
IPLSLVQAVSVAGVDLTDANLAGLTLRREGKDYLIDIDSLNRRDSQLSRIFLKDGDYLHL
CCHHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCHHHEEEEECCCEEEE
NSNSRNKIYVLGEVRNPQVISFGTTRLTLLEALGNSGGLSPDSADGDAVYVIRGAEDFAQ
CCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHH
APSTVYHLNAKKPTAYLLAGQFELKAQDVVFVGPADITRWSRFISQLLGSASVIQTGAAF
CCCEEEEEECCCCEEEEEEEEEEEEECCEEEECCHHHHHHHHHHHHHHCCHHHHHCCHHC
RN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]