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The map label for this gene is nuoN [H]

Identifier: 66046438

GI number: 66046438

Start: 3841188

End: 3842657

Strand: Direct

Name: nuoN [H]

Synonym: Psyr_3209

Alternate gene names: 66046438

Gene position: 3841188-3842657 (Clockwise)

Preceding gene: 66046437

Following gene: 66046444

Centisome position: 63.04

GC content: 60.54

Gene sequence:

>1470_bases
ATGGACCTGACGATTCAACACTTTATTGCGCTTGCGCCACTGCTGATCACCAGCCTCACCGTTGTCGTGGTGATGCTTGC
GATCGCATGGCGCCGCAATCACTCGCAAACGTTCCTGCTTTCGGTAGCAGGCCTCAACCTGGCCCTGCTGTCGATTTATC
CGGCATTGAAAGTCGCCCCTCTGGTCGTGACGCCACTGCTGCATATCGACAACTTTGCCTGCCTGTACATGGCGATCATC
CTCGCCTCTACCCTCGCTTGCGTGACCATGGCGCACGCCTATCTAGGTGACGGCAAGGCCGGGTATCCGGGCAATCGCGA
AGAGCTTTACCTGCTGATCCTGCTGGCAGCTGCCGGTGGACTGGTTCTGGTCAGCGCTCAGCATCTGGCGGGGCTGTTCA
TCGGCCTGGAACTGCTGTCGGTGCCGGTCTACGGGTTGGTGGCTTATGCCTTCTTCAACAAGCGTTCGCTGGAAGGCGGC
ATCAAGTACATGGTCCTGTCGGCTGCAGGCTCGGCGTTCCTGCTGTTCGGTATGGCGCTGCTGTACGCAGAGGCAGGCTC
GCTGAGCTTCGACGGTATCGGCAAGGCCATCGCGGCAACCGGCATGCCGAGCCCGATTGCCAGCCTGGGTCTGGGCATGA
TGGTCGTCGGCCTGGCCTTCAAGCTGTCACTGGTGCCGTTCCACTTGTGGACCCCGGACGTTTACGAAGGCGCCCCTGCG
CCGGTCGCTGCCTTCCTGGCAACTGCCAGCAAGGTGGCAGTGTTCGCGGTACTGGTGCGTCTGTTCCAGATTTCCCCGGC
AGCCAGCAGCGGTGTCTTGCATGATGTACTGGCAGTCATCGCCGTCGCGTCGATCCTCGTCGGCAACCTGCTGGCGCTGA
CTCAGACCAACCTCAAGCGTCTGCTGGGCTACTCCTCCATCGCCCACTTCGGTTACCTGATGATTGCGCTGGTGGCCAGC
AAGGGCATGGCGGTCGAGGCGATCGGCGTCTACCTGGCGACTTACGTCCTGACCTCGCTGGGCAGCTTCGGTGTGATCAC
CATGATGTCTTCGCCTTACAGCGGACGTGATGCCGACGCGATGTTCGAATACCGTGGACTGTTCTGGCGTCGCCCTTACC
TGACGGCAGTCATGACCCTGATGATGCTGTCGCTGGCAGGTATCCCGCTCACCGCAGGTTTCATCGGCAAGTTCTATATC
ATCGCCACTGGTGTCGAATCGCAGTTGTGGTGGCTGGTCGGGGCTCTGGTAATCGGTAGCGCCATCGGCGTGTTCTACTA
CCTGCGCGTGATGGTCACCATGTATTTGGTCGACAACAAGCTTCCTCGCCATGATGCAGCCATCAACTGGGCACAGCGCA
CGGGCGGCGTGATGCTGCTGGCCGTTGCGATCCTGACCTTCGTGCTGGGTGTGTATCCGCAACCGCTGCTCGATCTGGTG
CTCAATGCCGGTCTGCACGTAGCAGGCTGA

Upstream 100 bases:

>100_bases
CCGCAGCCGTTCCTCGACACATCGGCGGCGACCATGCACGGCGTGCAGCAATGGCTAGGCACTGCCTTCACTCAACTCGC
TTCGGCCCGGTAAGAGCGCT

Downstream 100 bases:

>100_bases
TCCAGCGCAAACAAAAAGCCCTGCTCTCGAGCAGGGCTTTTTTTTGTCTTCGAAAACGGCTAATGCCTGACGTCATGGGC
AAACGTGGCAATGCGTCCTT

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MDLTIQHFIALAPLLITSLTVVVVMLAIAWRRNHSQTFLLSVAGLNLALLSIYPALKVAPLVVTPLLHIDNFACLYMAII
LASTLACVTMAHAYLGDGKAGYPGNREELYLLILLAAAGGLVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEGG
IKYMVLSAAGSAFLLFGMALLYAEAGSLSFDGIGKAIAATGMPSPIASLGLGMMVVGLAFKLSLVPFHLWTPDVYEGAPA
PVAAFLATASKVAVFAVLVRLFQISPAASSGVLHDVLAVIAVASILVGNLLALTQTNLKRLLGYSSIAHFGYLMIALVAS
KGMAVEAIGVYLATYVLTSLGSFGVITMMSSPYSGRDADAMFEYRGLFWRRPYLTAVMTLMMLSLAGIPLTAGFIGKFYI
IATGVESQLWWLVGALVIGSAIGVFYYLRVMVTMYLVDNKLPRHDAAINWAQRTGGVMLLAVAILTFVLGVYPQPLLDLV
LNAGLHVAG

Sequences:

>Translated_489_residues
MDLTIQHFIALAPLLITSLTVVVVMLAIAWRRNHSQTFLLSVAGLNLALLSIYPALKVAPLVVTPLLHIDNFACLYMAII
LASTLACVTMAHAYLGDGKAGYPGNREELYLLILLAAAGGLVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEGG
IKYMVLSAAGSAFLLFGMALLYAEAGSLSFDGIGKAIAATGMPSPIASLGLGMMVVGLAFKLSLVPFHLWTPDVYEGAPA
PVAAFLATASKVAVFAVLVRLFQISPAASSGVLHDVLAVIAVASILVGNLLALTQTNLKRLLGYSSIAHFGYLMIALVAS
KGMAVEAIGVYLATYVLTSLGSFGVITMMSSPYSGRDADAMFEYRGLFWRRPYLTAVMTLMMLSLAGIPLTAGFIGKFYI
IATGVESQLWWLVGALVIGSAIGVFYYLRVMVTMYLVDNKLPRHDAAINWAQRTGGVMLLAVAILTFVLGVYPQPLLDLV
LNAGLHVAG
>Mature_489_residues
MDLTIQHFIALAPLLITSLTVVVVMLAIAWRRNHSQTFLLSVAGLNLALLSIYPALKVAPLVVTPLLHIDNFACLYMAII
LASTLACVTMAHAYLGDGKAGYPGNREELYLLILLAAAGGLVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEGG
IKYMVLSAAGSAFLLFGMALLYAEAGSLSFDGIGKAIAATGMPSPIASLGLGMMVVGLAFKLSLVPFHLWTPDVYEGAPA
PVAAFLATASKVAVFAVLVRLFQISPAASSGVLHDVLAVIAVASILVGNLLALTQTNLKRLLGYSSIAHFGYLMIALVAS
KGMAVEAIGVYLATYVLTSLGSFGVITMMSSPYSGRDADAMFEYRGLFWRRPYLTAVMTLMMLSLAGIPLTAGFIGKFYI
IATGVESQLWWLVGALVIGSAIGVFYYLRVMVTMYLVDNKLPRHDAAINWAQRTGGVMLLAVAILTFVLGVYPQPLLDLV
LNAGLHVAG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=215, Percent_Identity=29.3023255813954, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI145693160, Length=482, Percent_Identity=58.50622406639, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1788831, Length=267, Percent_Identity=26.5917602996255, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788613, Length=360, Percent_Identity=25.2777777777778, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788829, Length=358, Percent_Identity=24.8603351955307, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788614, Length=354, Percent_Identity=25.4237288135593, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788827, Length=282, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51858; Mature: 51858

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTIQHFIALAPLLITSLTVVVVMLAIAWRRNHSQTFLLSVAGLNLALLSIYPALKVAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHHHHHHHHHHHH
LVVTPLLHIDNFACLYMAIILASTLACVTMAHAYLGDGKAGYPGNREELYLLILLAAAGG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
LVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEGGIKYMVLSAAGSAFLLFGMAL
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
LYAEAGSLSFDGIGKAIAATGMPSPIASLGLGMMVVGLAFKLSLVPFHLWTPDVYEGAPA
HHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCC
PVAAFLATASKVAVFAVLVRLFQISPAASSGVLHDVLAVIAVASILVGNLLALTQTNLKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGYSSIAHFGYLMIALVASKGMAVEAIGVYLATYVLTSLGSFGVITMMSSPYSGRDADA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
MFEYRGLFWRRPYLTAVMTLMMLSLAGIPLTAGFIGKFYIIATGVESQLWWLVGALVIGS
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEEECCHHHHHHHHHHHHHHH
AIGVFYYLRVMVTMYLVDNKLPRHDAAINWAQRTGGVMLLAVAILTFVLGVYPQPLLDLV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH
LNAGLHVAG
HHCCCCCCC
>Mature Secondary Structure
MDLTIQHFIALAPLLITSLTVVVVMLAIAWRRNHSQTFLLSVAGLNLALLSIYPALKVAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCHHHHHHHHHHHHHHHH
LVVTPLLHIDNFACLYMAIILASTLACVTMAHAYLGDGKAGYPGNREELYLLILLAAAGG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
LVLVSAQHLAGLFIGLELLSVPVYGLVAYAFFNKRSLEGGIKYMVLSAAGSAFLLFGMAL
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
LYAEAGSLSFDGIGKAIAATGMPSPIASLGLGMMVVGLAFKLSLVPFHLWTPDVYEGAPA
HHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCC
PVAAFLATASKVAVFAVLVRLFQISPAASSGVLHDVLAVIAVASILVGNLLALTQTNLKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGYSSIAHFGYLMIALVASKGMAVEAIGVYLATYVLTSLGSFGVITMMSSPYSGRDADA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
MFEYRGLFWRRPYLTAVMTLMMLSLAGIPLTAGFIGKFYIIATGVESQLWWLVGALVIGS
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEEECCHHHHHHHHHHHHHHH
AIGVFYYLRVMVTMYLVDNKLPRHDAAINWAQRTGGVMLLAVAILTFVLGVYPQPLLDLV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH
LNAGLHVAG
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]