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The map label for this gene is nuoA

Identifier: 66046426

GI number: 66046426

Start: 3827706

End: 3828119

Strand: Direct

Name: nuoA

Synonym: Psyr_3197

Alternate gene names: 66046426

Gene position: 3827706-3828119 (Clockwise)

Preceding gene: 66046425

Following gene: 66046427

Centisome position: 62.81

GC content: 55.8

Gene sequence:

>414_bases
ATGCCCGAATCGACAGGTCTGATTGCCCACAACTGGGGCTTCGCCATTTTCCTTTTGGGTGTTGTCGGCCTTTGTGCCTT
CATGCTCGGTCTGTCCAGCCTGCTCGGAAGCAAGGCCTGGGGCCGCAGCAAGAACGAACCTTTCGAATCCGGCATGCTGC
CCACCGGCAGTGCGCGTCTGCGTCTCTCCGCAAAATTCTATCTGGTCGCGATGCTTTTCGTGATCTTTGACATTGAAGCC
CTCTTTCTCTTTGCCTGGTCTGTGTCCGTCCGCGAAAGCGGCTGGACCGGATTCGTCGAAGCTCTCGTTTTCATAGCAAT
TCTGTTGGCAGGTCTTGTCTACCTATGGCGGGTTGGCGCTCTTGACTGGGCTCCTGAAGGTCGCCGTAATCGGCAAGCGA
AGCTGAAACAATGA

Upstream 100 bases:

>100_bases
GCACATAAAATCAATCCGTTGACCGCACTGCGACATTTCGTCACTGCCTCGACTCTTTATCAAGCACAGAGACCTTTGCT
CTCTAACAAGGACTGACAGC

Downstream 100 bases:

>100_bases
GGCTTTGGCGATGCAATATAATCTCACCAGGATCGACCCGGACGCTCCTAACGAGCAGTACCCCATCGGCAAACGGGAAA
CCGTTTCCGATCCGTTAGAA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MPESTGLIAHNWGFAIFLLGVVGLCAFMLGLSSLLGSKAWGRSKNEPFESGMLPTGSARLRLSAKFYLVAMLFVIFDIEA
LFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLWRVGALDWAPEGRRNRQAKLKQ

Sequences:

>Translated_137_residues
MPESTGLIAHNWGFAIFLLGVVGLCAFMLGLSSLLGSKAWGRSKNEPFESGMLPTGSARLRLSAKFYLVAMLFVIFDIEA
LFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLWRVGALDWAPEGRRNRQAKLKQ
>Mature_136_residues
PESTGLIAHNWGFAIFLLGVVGLCAFMLGLSSLLGSKAWGRSKNEPFESGMLPTGSARLRLSAKFYLVAMLFVIFDIEAL
FLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLWRVGALDWAPEGRRNRQAKLKQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=132, Percent_Identity=67.4242424242424, Blast_Score=173, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_PSE14 (Q48H54)

Other databases:

- EMBL:   CP000058
- RefSeq:   YP_275279.1
- STRING:   Q48H54
- GeneID:   3556906
- GenomeReviews:   CP000058_GR
- KEGG:   psp:PSPPH_3109
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- PhylomeDB:   Q48H54
- ProtClustDB:   PRK06602
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 15143; Mature: 15012

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1be6a868)-; HASH(0x1faddc04)-; HASH(0x16cc6ee0)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESTGLIAHNWGFAIFLLGVVGLCAFMLGLSSLLGSKAWGRSKNEPFESGMLPTGSARL
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCE
RLSAKFYLVAMLFVIFDIEALFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLWRVGA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWAPEGRRNRQAKLKQ
CCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
PESTGLIAHNWGFAIFLLGVVGLCAFMLGLSSLLGSKAWGRSKNEPFESGMLPTGSARL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCE
RLSAKFYLVAMLFVIFDIEALFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLWRVGA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWAPEGRRNRQAKLKQ
CCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA